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BioPhotonics - May/Jun 2023


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Features
Pulsed Lasers Make Headway in Treating Cardiovascular Disease Patients with heart disease often face a daunting journey from diagnosis to treatment. They may learn, after experiencing chest pains or shortness of breath, that they have arteriosclerosis, or damaged arteries, through a test such as a coronary angiogram, which shows via x-rays whether blood vessels are restricted. In extreme cases, coronary artery bypass surgery is performed, which is a highly...
Intravascular Near-Infrared Spectroscopy Predicts Heart Attacks Lipoproteins carry cholesterol through the closed-looped vascular hematological highway of the human body. This cholesterol can embed itself into the artery walls at varying rates, depending on a...
Catheter Use Propels Optical Coherence Tomography in Interventional Cardiology Optical coherence tomography (OCT) is an interferometric imaging technique that uses light in the near-infrared spectrum to provide detailed, cross-sectional images of biological tissue. OCT is...
Intravital Multiphoton Microscopy Captures Dynamics of the Beating Heart Most people know the heart pumps blood to the body, but they may not realize that the blood that fills the four chambers of the heart provides no sustenance to the myocardium, or the heart muscle,...
Light Therapy Could Soon Treat Cardiac Arrhythmia Heart disease is the leading cause of death in the developed world. Sudden cardiac death is triggered by the breakdown of a normal periodic heart rhythm, also known as the sinus rhythm. The emergence...
Editorial
Clearing arterial plaques Nearly 18 million people died of cardiovascular disease worldwide in 2019, according to the World Health Organization. The biggest contributing factors are largely preventable — high blood pressure, diets with high fat and cholesterol content, smoking, excessive intake of alcohol and sugar, and sedentary lifestyles. Many of these behaviors contribute to the buildup of arterial plaques....
BioScan
Wearable Microscopes Image Transmission of Pain Signals Researchers at the Salk Institute for Biological Studies have developed wearable microscopes and an implantable microprism that together aim to help scientists uncover the role that the spinal cord...
3D Printing Eases Electronic Device Implantation A team led by researchers at Lancaster University has developed a method to 3D-print flexible electronics using a conducting polymer, and the team has demonstrated a method to directly print these...
Machine Learning Enhances Light-Field Imaging-Based Method Researchers from The Rockefeller University have developed an imaging technique that could allow scientists to penetrate the depth and breadth of the cortical areas of the brain at peak resolution,...
Chip-Scale Spectrometer Points to Portable Instrumentation Scientists at the Chinese University of Hong Kong have developed an approach to chip-scale spectrometry that offers both high spectral resolution and optical bandwidth. The researchers designed and...
Wavefront Shaping Improves Tissue Imaging for Disease Detection Wavefront shaping is used to reverse the optical distortion caused by Earth’s atmosphere and provide clear images of distant planets. Beyond astronomy, wavefront shaping in biomedicine is...
Superresolution Captures Conformational Changes in Proteins Researchers led by Nobel laureate Stefan Hell at the Max Planck Institute for Medical Research have developed a superresolution microscope with a spatiotemporal precision of 1 nm/ms. The work builds...
SpectraWAVE Secures FDA Clearance for Intravascular Imaging Tech Medical imaging company SpectraWAVE has received 510(k) clearance from the Food and Drug Administration (FDA) for its intravascular imaging system, HyperVue. The dual modality system combines OCT and...
First Heart Patients Diagnosed Using Ultrathin Fiber Optic Sensor Medical personnel have used a fiber optics sensors-based diagnostic technology to detect the causes of heart disease for the first time in patients. The device, developed by University College London...
BluGlass Names its Company President Haden as CEO Semiconductor technology company BluGlass Ltd. has appointed company president Jim Haden to the position of CEO. Haden joined the company in September 2021. BluGlass named laser industry veteran and...
Laser Method Boosts Accuracy of Blood Flow Measurements in Feet Researchers from Aston University have developed a method to improve the accuracy of blood flow measurements in the feet of patients with Type 2 diabetes. The laser-based technique improves accuracy...
Cytek Biosciences Acquires Flow Cytometry Business from DiaSorin Cytek Biosciences has signed an agreement with DiaSorin subsidiary Luminex to acquire substantially all of its assets related to the Flow Cytometry and Imaging (FCI) business unit. The acquisition...
Novel Platform Reveals Insights into Control of Brain Network Researchers at the University of North Carolina (UNC) School of Medicine combined fiber photometry with functional magnetic resonance imaging (fMRI) to examine the dynamic activity of brain regions...
Project to Use Quantum Imaging to Track the Pathology of Tumors A project funded by the German Federal Ministry of Education and Research will investigate the viability of quantum optical imaging for tumor diagnostics. Nine project partners, including TU...
Ocean Insight Turns Back Clock for Corporate Rebrand Spectral technology company Ocean Insight will relaunch its Ocean Optics brand, which the company used from its founding in 1989 until retiring the brand in 2019. The move comes as part of a company...
Dxcover Raises $11.9M to Advance Liquid Biopsy Platform Glasgow, Scotland-based startup Dxcover has raised $11.9 million in series A and grant financing to support the development of its liquid biopsy technology platform for the detection of early-stage...
Module Uses Single-photon Microscopy to Track Cellular Activity BrightEyes-TTM, an open-source time-tagging module (TTM) developed at the Italian Institute of Technology (IIT), enables scientists to observe the dynamic processes of molecules inside living cells...
3 Questions
3 Questions with Andre Faubert Andre Faubert, a biomedical engineering undergraduate at the Stevens Institute of Technology, discusses his research with Shang Wang's Biophotonics Lab surrounding 4D OCT and embryonic mouse heart development.
BioOpinion
Photonics improves interventional cardiology Cardiovascular disease is the world’s number one killer, taking the lives of an estimated 17.9 million people globally each year. The disease took more than 800,000 lives in the U.S. in 2020, according to the American Heart Association. Heart disease costs the U.S. over $400 billion each year. A better way is needed to address cardiovascular disease, and optical technologies are helping to...
Postscripts
Stress tests borne of mice and men Men and women respond differently to stimuli, and their hearts respond differently, too. Scientists are continuing to develop an understanding as to why these disparities in physical reactions exist. Before studying the differences in human hearts, a group of scientists at the University of California, Davis started smaller, with male and female mice, to explore whether the way mouse hearts...
Products
Flow Cytometry Optical Filters The Semrock® line of Nanopede™ optical filters from IDEX Health & Science LLC are designed for flow cytometry applications. Covering the visible spectrum in 20-nm full-width, half-maximum steps, the filters are designed to match the rapidly developing flow cytometry market. Custom optical filters can meet specific application needs. Flow cytometry interrogates cells through...
IDEX Health & Science - Semrock Optical Filters
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Kinetic Plate Imager The FDSS-GX kinetic plate imager from Hamamatsu Photonics KK is designed for kinetic cell-based assay development including G-protein-coupled receptors or ion channel research and screening for drug...
Hamamatsu Corporation
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Confocal Raman Spectrometer CRAIC Technologies’ Apollo M™ is a confocal Raman microspectrometer that adds to an optical microscope setup, enabling the user to measure Raman spectra of microscopic samples. Designed...
CRAIC Technologies
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Light Inverted Microscope Leica Microsystems’ Mateo TL is a digital transmitted light inverted microscope for cell culture routine. Setup of the microscope can be achieved in under one minute. Once set up, cell culture...
Leica Microsystems GmbH
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Sapphire Medical Optics Meller Optics' sapphire lenses, windows, and prisms are designed for use in medical lasers, endoscopes, oximeters, and other instruments. Meller Sapphire Medical Optics are suited for instruments in...
Meller Optics Inc.
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Tunable Laser System The Tunable Laser System from Spectrolight Inc. is an all-in-one tunable light source system that enables precise selection of a broad spectral range from 410 to 1650 nm and easy bandwidth adjustment...
SPECTROLIGHT Inc.
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Multimode Plate Reader The EnVison® Nexus™ Multimode Plate Reader from PerkinElmer Inc. drives improved research and discovery workflows for demanding high-throughput screening applications and drug discovery...
PerkinElmer US LLC
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Dermatologic Laser The Waterlase Fractional Handpiece from Biolase Inc. is a dermatologic laser for skin resurfacing featuring an erbium, chromium, yttrium, scandium, gallium, garnet (Er,Cr:YSGG) laser and water...
BIOLASE Inc.
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Refractometers Polaris™ Process Refractometers from Vaisala Oyj are designed to optimize industrial manufacturing processes. The devices are used for inline liquid concentration measurements for various...
Vaisala Inc.
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Mass Photometer The SamuxMP Auto mass photometer from Refeyn Ltd. reduces manual operation time while increasing reproducibility in adeno-associated virus (AAV) characterization. The benchtop automated mass...
Refeyn Ltd.
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Multispectral Camera The Unispectral Monarch II multispectral camera from Bodkin Design & Engineering LLC is a NIR camera integrated with a tunable Fabry–Pérot filter. Weighing 30 g, it can be...
Bodkin Design & Engineering LLC
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Deep-UV Lasers Three deep-UV lasers from IPG Photonics Corp. feature proprietary nonlinear crystals for reliability in numerous industries and micromachining applications. The fiber-based architectures...
IPG Photonics Corporation
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Femtosecond Laser The Jasper Micro compact femtosecond laser from Fluence Technology is air-cooled and compact for integration in limited space. Pulse duration is tunable from <270 fs to 8 ps, and optionally...
Fluence sp. z o.o.
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Monochrome Microscope Camera The Digital Sight 50M monochrome microscope camera from Nikon Instruments Inc. conducts high-precision analysis and large-volume sampling for use in applications such as well plate screening. ...
Nikon Instruments Inc.
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Femtosecond Laser The Chromacity 920 laser source is designed for two-photon microscopy and the excitation of key fluorophores and calcium markers. The fiber-based technology enhances multi-photon imaging with...
Chromacity Ltd.
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Spectrometer The Pacto Spectrometer from Avantes BV can be used in applications ranging from in-line quality control in fruit sorting to blood analysis in medicine. The compact device is available in...
Avantes BV
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Live-cell Imaging Platform The Omni Pro 12 Live-Cell Imaging Platform from Axion BioSystems Inc. features integrated robotics and a multi-plate design compatible with any standard incubator for scientists and drug developers...
Axion BioSystems
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Gallium Nitride Lasers Gallium nitride (GaN) lasers from BluGlass are available in 405-, 420-, and 450-nm wavelengths, with single- and multimode options. Users can inspect performance data and select from a range of...
BluGlass Ltd.
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Beam Shaper The πShaper 12_12_2.05_HP from AdlOptica Optical Systems GmbH is a beam shaper for high-power 2-µm lasers. The near-IR beam shaper transforms a Gaussian laser beam into a flat-top beam...
AdlOptica GmbH
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Bandpass Filters The ADVANTECH™ hard coat bandpass filters from Andover Corp. offer steep slopes, high light transmission, durability, and long life for demanding applications. The filters provide...
Andover Corporation
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Raman Fiber Laser Module The 150-W Raman Fiber Laser Module from OFS leverages the Fiber Laser Building Block platform for rapid customer integration and development. The system serves as a high-brightness pump source...
OFS
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Hexapod The SOLANO hexapod from Symétrie is an ultra-compact device of 104 × 120 mm for precision positioning applications in industry or research. Designed to position up to 5-kg...
Symetrie
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UVC LEDs The SF1 far UV-C 235-nm LED series and the SN3 deep UV-C 255-nm LED series from the Silanna Group are available in either 120° or 30° viewing angle surface-mount packages. Both the SF1...
Silanna UV
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