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BioPhotonics - Mar/Apr 2025


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Features
Simplifying Flow Cytometry Through Panel Design Flow cytometry is an analytical technique that enables rapid, high-resolution analysis of diverse cell populations at high throughput. In fields such as immunology, oncology, and drug discovery, the ability to identify different cell types from a test sample suspended in fluid accelerates breakthroughs in understanding disease mechanisms and effective therapies. By using antibodies conjugated to...
Dynamic Light-Scattering Method Confirms Alzheimer’s Disease Study Results Alzheimer’s is a slowly progressing disease caused by physical changes in the brain, resulting in the loss of mental abilities and memory. Unfortunately, a simple clinical test does not exist...
Machine Learning Boosts Speed and Quality of Second-Harmonic Generation Microscopy In biological research, the visualization of tissue structures is critical for understanding their function as well as in tracking the progression of diseases in various stages. Second-harmonic...
The Evolution of Fluorescence Illumination Is Refining Medical and Research Applications Innovations in biomedical illumination technology are transforming various aspects of medical procedures, imaging techniques, and therapeutic interventions. Improved illumination enables surgeons to...
SPIE Names 2025 Prism Award Winners SPIE, the international society for optics and photonics, recognized the top innovations in new optics and photonics products at the 2025 Prism Awards held at Photonics West on Jan. 29. The gala...
Editorial
Second harmonic generation reveals system structure Second-harmonic generation (SHG) microscopy has advantages in biomedical research, such as low phototoxicity along with high resolution and deep penetration of tissue. Michael Zachariadis, who manages instruments in the Imaging Facility at the University of Bath, said their lab has been used for identification of collagen structure in swine or the tracking of cellular interactions in zebrafish....
Event Preview
Translational Technology Takes Center Stage at Biophotonics Congress 2025 The long — but vital — path that microscopy, laser treatments, and other biomedical and life sciences technologies take from the conception of a prototype to actual usable instrumentation in a laboratory or clinic will be a key topic of discussion at Optica’s 2025 Biophotonics Congress: Optics in the Life Sciences. Topics of talks and sessions (as well as student posters) range from device...
BioScan
Partners Integrate Cytometers with Robotics Capabilities Medical technology company Becton, Dickinson and Company (BD) and laboratory automation solutions developer Biosero have established a collaboration agreement to facilitate robotic integration with BD flow cytometry instruments to accelerate drug discovery and development. The first systems are expected to be available for research use later this year. The companies intend to develop new software...
Conical Polymer Fibers Reduce Inflammation Risk for Optogenetics To deliver light to the brain safely and efficiently, a research team at the Technical University of Denmark designed tapered optical fibers made with soft, biocompatible polymer. The tapered fibers...
Time-Shared Optical Tweezers Ease Study of Viscoelasticity A technique to study the link between physiological aging and disease, from the Institute of Photonic Sciences (ICFO), uses single-laser-based optical tweezers to measure the viscoelasticity of...
Edmund Optics Acquires son-x Edmund Optics has acquired son-x, a developer of ultrasonic assist systems and high precision optics manufacturing. Financial terms of the acquisition were not disclosed. Fraunhofer spin-off son-x...
Bioluminescent Tags Track RNA Dynamics in Live Cells A bioluminescent tag that can be attached to ribonucleic acid (RNA) will enable scientists to track RNA in real time as it moves through the human body. To understand the central role of RNA in...
Thorlabs Buys VCSEL Developer, longtime Partner Praevium Research Thorlabs has acquired longtime collaborator Praevium Research, a developer of high-speed tunable VCSELs. As a division of Thorlabs, Praevium will continue to operate out of its current location in...
Exail Acquires Laser-Maker Leukos Exail has acquired laser technology company Leukos, a company specializing in advanced laser sources for metrology, spectroscopy, and imaging applications. Financial terms of the acquisition were not...
Advanced OCT System Integral to Eye Transplantation An adaptation of optical coherent tomography put into use at Northwestern University, visible OCT (vis-OCT), will be a key component in an ARPA-H funded project that aims to conduct successful eye...
NIR Diffuse Optic, Ultrasound Device Characterizes Thyroids Thyroid diseases affect approximately 200 million people worldwide. In most thyroid pathologies, the vascularization – the number and structure of blood vessels – and hemodynamics are...
Miniature Microscopes May Probe Hard-to-Reach Places in the Body A technique from researchers at the University of Adelaide could enable microscopic imaging to be performed through a very thin optical fiber. The new technique could make it possible to image areas...
PhotoniCare Raises $4.6M, Establishes Manufacturing Partnership Medical device company PhotoniCare has secured $4.6 million in a series B funding round and formed a manufacturing partnership with Gentex Corporation, who led the funding, to produce its OtoSight...
BioOpinion
Lack of Standards Limits Fluorescence-Guided Surgery Fluorescence-guided surgery has been approved for clinical use for the last 20 years. But the field suffers from a critical blind spot: the lack of standardized characterization methods for imaging systems and contrast agents. Many of the 30 systems on the market are designed to work with indocyanine green (ICG), a fluorophore that is excited by near-infrared light (750 to 800 nm) and emits...
Postscripts
Seein’ somethin’ through sea sponge skeletons We’ve all heard the phrase “life imitates art”: a philosophical observation that real life events seem to mimic fictional occurrences found in popular media. For example, you might start reading Twenty Thousand Leagues Under the Sea and start noticing more and more gigantic submarines coasting alongside your local pier, or rewatch “Finding Nemo” for the umpteenth...
Products
Biomedical Illumination Platform The X-Cite® Vitae vIRX from Excelitas Technologies is an illumination platform for high-precision medical illumination and diagnostic applications such as endoscopy and surgical visualization, as...
Excelitas Technologies Corp.
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OCT Spectrometer The EAGLE OCT-S 140 from Ibsen Photonics is an OCT spectrometer for uses in home use, pharmacy, optometry, and industrial applications. The 140-nm bandwidth spectrometer has a high axial resolution...
Ibsen Photonics A/S
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Fiber-Coupled Pumps The FACTOR Series from Coherent are fiber-coupled diode pumps for both medical and industrial applications. The pumps use VBG stabilization for hop-free operation over a range of optical output...
Coherent Corp.
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Laser Modules The Chilas ATLAS, COMET (shown), and POLARIS from Chilas BV are laser modules meant for applications such as sensing, quantum technologies, OCT, QKD, lidar, spectroscopy, telecommunications, and...
Chilas BV
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Medical SPAD Sensor The Andarta from Singular Photonics, in collaboration with Meta, is a single photon avalanche diode (SPAD) sensor meant for use in medical applications such as monitoring cerebral blood flow and...
Singular Photonics
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Broadband SLEDs EXALOS’ line of 840-nm broadband superluminescent light-emitting diodes (SLEDs) supports applications such as industrial and biomedical optical coherence tomography. The devices deliver 100 mW...
Exalos AG
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Laser Interferometer The Modulo Quatro from Sound & Bright is a multipoint laser interferometer meant for nondestructive testing in applications such as biomedical. The interferometer uses multichannel random...
Sound & Bright
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Infrared Imaging Microscope The LUMOS™ II ILIM from Bruker Corporation is a quantum cascade laser-based infrared imaging microscope meant for applications such as capturing ultrafast infrared images of expansive areas...
Bruker Optics Inc.
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Single Molecule Microscope The Aplo Scope from ONI is a single molecule super-resolution microscope for observing and measuring molecular interactions within cells and tissues. The microscope transitions from low-power...
Oxford Nanoimaging Ltd. (ONI)
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Diode Laser Components The 08BULT Diode Laser Components from Frankfurt Laser Company is a solution designed for applications such as medical technologies and material processing. The laser series uses RealLight’s AW...
Frankfurt Laser Company
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Alpha-Beta Goniometers The AK150-10-15 Series from Optimal Engineering Systems are dual-axis alpha-beta goniometers for applications such as examining cutting edges of medical instruments, estimating hyperspectral...
Optimal Engineering Systems Inc.
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TDI Imagers The GLT5008BSI (shown) and GLT5016BSI from Gpixel are backside illuminated (BSI) time delay and integration (TDI) line-scan imagers for semiconductor inspection and life science applications. The...
Gpixel Inc.
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SWIR LEDs The OCI-490 series from EPIGAP OSA Photonics GmbH is a series of SWIR LEDs for sorting and quality control tasks in pharmaceutical, medical, defense, and agricultural industries among others. The...
EPIGAP OSA Photonics GmbH
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CO2 Marking Lenses Laser Research Optics’ line of marking lenses are CO2 optics for lasers used in marking medical and surgical devices requiring permanent identification and/or serialization. The optics meet...
Laser Research Optics
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