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The Long and Short of Biomedical Imaging
What you can’t see can hurt you. Cancer and other diseases can remain undetected until it’s too late. On the other hand, sometimes what you can’t see can help you: Increasingly, photons in nonvisible wavelengths are being used to spot disease, providing a picture that couldn’t be captured otherwise. For example, thanks to advances in detectors, smaller x-ray doses can provide more complete information. At the other end of the spectrum – literally – infrared imaging, which uses nonionizing...
BioPhotonics, May 2009
The Stimulus Package and You
On Tuesday, Feb. 17, President Obama signed into law the American Recovery and Reinvestment Act (ARRA), the much-debated stimulus package designed to breathe life into the US economy. The act included a remarkable $10.4 billion for the National...
BioPhotonics, May 2009
These optical fibers could save lives
A start-up company is developing fibers that could provide real-time information as cardiologists open clogged arteries. Another start-up is using fibers to enable gastroenterologists to search the esophagus and colon for tissue that could become...
BioPhotonics, May 2009
Microfluidic Systems make the Impossible Possible
According to the Jan. 15, 2009, Genetic Engineering and Biotechnology News, the market for microfluidic technology will climb toward $1.9 billion over the next three years. Shown are LabChips made by Caliper for the Agilent 2100...
BioPhotonics, April 2009
Open Wide
It’s no surprise that William Brown is certain the future of lasers in dentistry is bright. After all, he is a vice president at dental laser maker Biolase Technology Inc. in Irvine, Calif. But that feeling is based on more than his job. It rests,...
BioPhotonics, April 2009
Shedding a New Light on Cancer
The recent high-profile pancreatic cancer cases of actor Patrick Swayze and Apple CEO Steve Jobs have called attention to the more than 37,000 Americans who are diagnosed with the disease each year, according to the National Cancer Institute....
BioPhotonics, April 2009
Unlocking Epilepsy’s Secrets
Their goal is to understand the epileptic brain. And the key just might be fluorescence lifetime imaging microscopy – also known as FLIM. Michael J. Levene, assistant professor of biomedical engineering at Yale University in New Haven, Conn., and...
BioPhotonics, April 2009
Laser Destroys Brain Tumors
Drs. Bernard Bendok and Andrew Fishman at Northwestern Memorial Hospital in Chicago reported in January that they had become among the first surgeons in the world to use the Beampath Neuro laser system from OmniGuide Inc. of Cambridge, Mass....
BioPhotonics, March 2009
Look Into My Eyes
The eyes have it, at least when it comes to new, noninvasive diagnostics. For example, there’s optical coherence tomography, or OCT. Improved OCT technology promises better monitoring and treatment of glaucoma and age-related macular degeneration,...
BioPhotonics, March 2009
Medical Laser Market: There Won't Be Blood
The medical laser arena is both large and diverse, encompassing a range of application areas and covering treatment from diagnosis to therapy. Here we explore trends in some of those areas and discuss how they might affect the market for medical...
BioPhotonics, March 2009
Mending Broken DNA
DNA is susceptible to continuous egregious environmental and biological hazards that can significantly damage its composition. Cellular exposure to radiation from x-rays and UV light, including free radicals and chemicals, can cause DNA to break....
BioPhotonics, March 2009
Digital Pathology Is Growing Despite Fears
In research hospitals and in the pharmaceutical industry, pathologists have been using special scanners to record digital images of tissue slides. Now these digital pathology scanners are expanding from research markets into what is projected to...
BioPhotonics, February 2009
Getting the complete picture
Despite what is often seen on screens, the world isn’t flat – and neither are people. That’s why three-dimensional imaging is important. The full picture of a volume can provide vital information about a medical condition and the progress of any...
BioPhotonics, February 2009
Close-Up on forensic microscopy
When it comes to the role of the microscope in forensics, Richard E. Bisbing is very clear. “Microscopy is essential to the forensic sciences and has been since the beginning – the 19th century,” he said. “Virtually all trace evidence requires...
BioPhotonics, January 2009
Cosmetic laser procedures are a big hit
According to statistics released in May 2008 by the American Society for Aesthetic Plastic Surgery for the year 2007, aesthetic procedures comprise an $11.7 billion market, and Americans are seeking 457 percent more cosmetic procedures compared with...
BioPhotonics, January 2009
Dissecting the rainbow
Spectroscopy may not be the longest-reigning example of the sciences we now group together as photonics, but it has had a long and very successful tenure at helping people understand the processes that sustain – and occasionally diminish –...
BioPhotonics, January 2009
Is OCT Worth It?
Optical coherence tomography (OCT) enables ophthalmologists to view details of the structures of the human eye, noninvasively and with submicron resolution. In 2006, the FDA approved the use of spectral domain OCT, which offers higher definition, a...
BioPhotonics, January 2009
Biosensors That Protect and Serve
Between natural and man-made hazards, it’s a dangerous world out there. The good news is that, along with problems, people can provide solutions. Two recent examples show how researchers have turned to biological-based sensors, or biosensors, to...
BioPhotonics, December 2008
Functional Imaging & MRI
The National Cancer Institute estimated that 1,437,180 people would be diagnosed with cancer in 2008 and that 565,650 people would die of the disease. Cancer research is, of course, ongoing, and recent decades have seen great strides in our...
BioPhotonics, December 2008
Photoacoustic Imaging Gets Dynamic
Photoacoustic imaging offers tremendous potential for both research and clinical applications because it draws on the advantages of both spectroscopy and ultrasound imaging. To date, researchers have applied the technique primarily for static...
BioPhotonics, December 2008
Play It Safe With Medical Lasers
When lasers are introduced into a health care environment – whether a hospital, surgery center or physician’s office – professionals must be prepared to address safety issues concerning both the staff and patient. All lasers present hazards to the...
BioPhotonics, December 2008
Making Live-Cell Imaging Glow
Live cells represent vital model systems for studying organism development and human disease. Functional, molecular and morphologic quantitative fluorescence imaging techniques are important tools that provide data about the biochemical, genetic or...
BioPhotonics, November 2008
Small Animals, Big Promise
In light of rising health care costs, technology that improves the efficiency of medical research is welcome. Small-animal imagers promise to streamline therapy development by imaging biological processes in mouse or rat models of human disease....
BioPhotonics, November 2008
This Time, It’s Personal
Medicine in the near future will be based more on each patient’s unique genetic code – a phenomenon often referred to as personalized medicine.1–3 Certain drugs already target proteins produced in patients or replace proteins not produced as a...
BioPhotonics, November 2008
Putting a Shine onNew Fluorescent Proteins
Thanks to ongoing efforts by researchers, fluorescent proteins continue to shine. Recent developments have taken advantage of growing knowledge to engineer brighter proteins, to produce ones that are more photostable and to create pairs that can be...
BioPhotonics, October 2008
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