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Imaging Technology, Experimentation Converge at SPIE BiOS
A host of researchers and industry experts will descend on SPIE BiOS 2020 in February to expound upon — and demonstrate — the ability of optical technologies to analyze, diagnose, and treat a multitude of medical conditions that clinicians grapple with every day. And while dermatology will be a component of this year’s conference, innovations within the biophotonics sphere have proven to be more than just skin deep, providing key insights into areas such as cardiology, head and neck surgery,...
BioPhotonics, Jan/Feb 2020
Medical Lasers, Confocal Microscope Among 2020 Prism Award Finalists
A line of lasers devised for neurosurgery. An FDA-cleared semiconductor laser for treating glaucoma — smaller and less expensive than others on the market. These technologies were among the 27 finalists for the 2020 Prism Awards, in categories...
BioPhotonics, Jan/Feb 2020
Medical Imaging Technology Exploits Light, Sound
Photoacoustic imaging, or the use of light to create sound, can result in better diagnoses of solid tumors in breast, thyroid, and other cancers, as well as reveal the development of Crohn’s disease, vascular disease, and other conditions. And...
BioPhotonics, Jan/Feb 2020
Hyperspectral Remote Sensing, Field Spectrometry Monitor Environment
Environmental monitoring involves the sampling and analysis of soil, water, or plants for evidence of change over time. This process informs decisions surrounding potential health risks and corrective actions. As the human population continues to...
BioPhotonics, Jan/Feb 2020
Multiphoton Microscopy Points Imaging to New Depths
While multiphoton excitation is now firmly established as a front-line tool in microscopy, it is still an evolving field producing a steady stream of new applications and techniques, all supported by advancements in lasers and microscopes. A key...
BioPhotonics, Jan/Feb 2020
Raman Spectral Cytology Helps Diagnose Thyroid Cancer
The thyroid is a butterfly-shaped gland in the neck that is responsible for secreting hormones that affect the metabolism and growth of almost every cell in the body. Bodily functions such as temperature, digestion, and heart rate are all regulated...
BioPhotonics, Jan/Feb 2020
The Eyes Behind Surgical Robots
The first robotic surgery took place in 1985 when the PUMA 560 was used in a stereotaxic operation in which computed tomography (or x-ray) was used intraoperatively to guide a robot as it inserted a needle into the brain for biopsy. In the late...
Photonics Spectra, April 2020
Deconvolution Helps Break Down Imaging Barriers
Deconvolution is a computationally intensive image processing technique used to improve the contrast and sharpness of images captured with a light microscope. Light microscopes are diffraction limited, which means they are unable to resolve...
BioPhotonics, Nov/Dec 2019
Compressive Raman Bioimaging: The Need for Speed in Medicine
Conventional bright-field microscopy is the standard for biomedical imaging because it provides cost-effective clinical analysis. However, for researchers and clinicians to assess tissue images accurately, years or even decades of experience are...
BioPhotonics, Nov/Dec 2019
The American Society for Cell Biology Looks to Convert Research into Reality
The 2019 Annual Meeting and Conference of the American Society for Cell Biology and European Molecular Biology Organization (ASCB|EMBO) will be held Dec. 7-11 at the Walter E. Washington Convention Center in Washington, D.C. Attendees will learn...
BioPhotonics, Nov/Dec 2019
Quantitative Phase Imaging Aims at Penetrating Thick Tissues
In 1942, phase microscopy revolutionized biological imaging because it enabled clear visualization of cells and their internal contents without labels or stains. This empowered biologists to study these transparent, living objects over long periods...
BioPhotonics, Nov/Dec 2019
Fluorescence Microscopy: Getting the Picture Right
Fluorescence microscopy is a very broadly used term covering numerous applications. It ranges from basic life science applications such as time-lapse cell viability assays — in which dead cells are counted as they start to fluoresce by intrusion of...
BioPhotonics, September 2019
Optics Peers Through the Haze of Dementia
As the number of people suffering from Alzheimer’s disease (AD) and related dementias grows, so too does the pressure on the medical community to identify dementias as early as possible and potentially treat them. Researchers on both sides of...
BioPhotonics, October 2019
Commercial Small Animal Imaging Could Aid Disease Detection
The development of anticancer metastatic therapies for human clinical trials requires meticulous evaluation of efficacy and optimization of small animal test models in preclinical experimentation. Critical information on morphology and the molecular...
BioPhotonics, October 2019
Nano-Optic Endoscope Gets Clearer View of Organs
The emergence of innovative imaging techniques has enabled several medical applications in detection, diagnosis, and monitoring of diseases. However, there still exists a gap in the imaging of internal organs where tissues are not readily...
BioPhotonics, October 2019
Biomedical Photoacoustics Reverberates in Clinics
Shortly before Alexander Graham Bell’s death in 1922, the Scottish American scientist and inventor said the telephone was not what he regarded as his greatest achievement. Rather, that distinction went to a now little-known device called the...
BioPhotonics, October 2019
Q&A Spectroscopy gives clear view of data
Spectroscopy is a broad field comprising a variety of methods and modalities, and covering applications from industry process control and security to biomedical. Each modality has its particular advantages and disadvantages, including speed,...
BioPhotonics, September 2019
Neuroscience 2019 Celebrates SfN’s 50th Anniversary
This fall, scientists and researchers from around the world will gather at the Neuroscience 2019 conference to hear lectures such as “Wavefront Engineering: Illuminating the Neural Landscape,” from Valentina Emiliani of the Vision...
BioPhotonics, September 2019
VIS-OCT Opens Eyes to New Approaches
First reported in 1991 by Huang and colleagues, OCT has become an important imaging tool for ophthalmology following innovations over the past three decades. OCT noninvasively provides 3D in vivo optical biopsy with microscopic resolution in the eye...
BioPhotonics, September 2019
Lens-Free Microscopy Focuses on Commercialization
With advancements in image processing and sensors, lens-free microscopy is ready for a closer look by researchers, industry, and consumers. Compared to traditional benchtop microscopes, lens-free techniques can cost less, reduce instrument size,...
BioPhotonics, September 2019
Open-Source Photon Counting Advances Biological Research
A surgeon removing a malignant tumor, a security agent detecting harmful molecules at a stadium, an autonomous car avoiding a collision, a weather satellite spotting hurricane formations, a neuroscientist tracking neuronal activity deep within the...
BioPhotonics, September 2019
Coherent Diffraction Imaging Expands Researcher Tool Set
Both optical and x-ray microscopy are well-established tools, but nanoscale imaging with light in the intermediate range — specifically the extreme UV (λ ~8 to 80 nm) — has been neglected. This has been primarily because of a gap...
BioPhotonics, Jul/Aug 2019
Innovations in Flow Cytometry Expand Its Use in Clinical Diagnostics
The outstanding achievements of immunologists James P. Allison and Tasuku Honjo — winners of the 2018 Nobel Prize for medicine for their discovery of cancer therapy by inhibition of negative immune regulation — are at the forefront of an...
BioPhotonics, Jul/Aug 2019
NIRS Surpasses Conventional Diagnostics for Orthopedics
As the aging population continues to grow, the number of people suffering from musculoskeletal diseases, such as osteoarthritis (OA), is expected to drastically increase. The symptoms of OA are diverse and include pain, soreness, and stiffness of...
BioPhotonics, Jul/Aug 2019
Multispectral Imaging Aids Wound Healing, Pathology Research
From airborne mapping to astronomical imaging to manufacturing inspection, multispectral imaging (MSI) has long been the go-to tool for extracting crucial details, often from distant views. Today, MSI is making promising inroads in biomedical...
BioPhotonics, Jul/Aug 2019
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