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Photoacoustic Imaging Identifies Transplantable Kidneys

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The technology uses both light and sound to track increasing levels of fibrosis in donated kidneys.

ENO HYSI AND DARREN A. YUEN, ST. MICHAEL’S HOSPITAL; AND MICHAEL C. KOLIOS, RYERSON UNIVERSITY

Chronic kidney disease is a condition that causes the gradual loss of kidney function over a period of months to years. The prevalence of the disease is worsened by the alarming rise of diabetes and hypertension, two of the most common causes of renal failure. The goal of most therapies is to merely slow the progression of the disease. Fortunately, a modern technology called photoacoustic imaging, involving the use of both light and sound, is helping to assess the most efficient treatment for chronic kidney disease: kidney transplantation. Courtesy of...Read full article

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    Published: December 2020
    Glossary
    photoacoustic imaging
    Abbreviated PAI. An imaging modality with a hybrid technique based on the acoustic detection of optical absorption from endogenous chromophores or exogenous contrast agents. Light is absorbed by the chromophores and converted into transient heating, and through thermoelastic expansion there is a resulting emission of ultrasonic waves. In tissue, ultrasound scatters less than light, therefore PAI generates high-resolution images in the diffusive and optical ballistic regimes compared to purely...
    Featuresphotoacoustic imagingtransplantfibrosischronic kidney diseasecollagenhypoxiahemoglobinunilateral ureteral obstructionImagingBiophotonics

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