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Microfluidic HIV Test: Quick and Cheap

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DAVIS, Calif., July 20, 2010 — A new lab-on-a-chip HIV testing device could make testing in developing nations easier and more affordable. UC Davis biomedical engineer Alexander Revzin developed the microfluidic device, which uses antibodies to “capture” white blood cells called T-cells that are affected by HIV. In addition to physically binding these cells, the test detects the types and levels of cytokines, or inflammatory proteins, released by the cells. Revzin’s team collaborated with UCLA electrical engineer Aydogan Ozcan to integrate an antibody microarray with a lens-free holographic...Read full article

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    Published: July 2010
    Glossary
    lab-on-a-chip
    A lab-on-a-chip (LOC) is a miniaturized device that integrates various laboratory functions and capabilities onto a single, compact chip. Also known as microfluidic devices, lab-on-a-chip systems are designed to perform a variety of tasks traditionally carried out in conventional laboratories, but on a much smaller scale. These devices use microfabrication techniques to create channels, chambers, and other structures that facilitate the manipulation of fluids, samples, and reactions at the...
    Alexander RevzinAmericasAnalytical ChemistryAydogan OzcanBasic ScienceBiophotonicsblood transfusionsCaliforniaCD4CD8cytokinesenergyhepatitis CHIVImaginglab-on-a-chiplens-free holographic imagingmultiparameterpolymer filmResearch & TechnologyT-cellsTest & MeasurementUC DavisUCLA

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