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Positioning Equipment: Enabling Technology for Life Sciences
Industry experts offer an inside look at the current state of positioning technologies for bio-related microscopy. Positioning systems and equipment are sometimes the unsung heroes of microscopy: Users often focus more on the optics and the light sources than on the devices that keep the rest of the system stable enough for death-defying feats of resolution and imaging depth. But that stability is vital – without it, further advances in biological research might not be possible.
BioPhotonics, September 2014
Ultrafast Temporal Shaping Is Coming of Age
Temporal shaping will play a significant role in the emerging femto revolution, especially for futuristic biomedical applications. Thanks to advances in ultrafast laser design, ultrafast laser sources have emerged from the laboratory and are now...
BioPhotonics, September 2014
Ultrashort-Pulse Laser Micromachining Advances Implantable Medical Devices
New femtosecond lasers are enabling the development and fabrication of bioabsorbable and ultrafine metal stents for novel treatments. Implantable medical devices such as stents, intraocular lenses, prosthetics and catheters are becoming increasingly...
BioPhotonics, September 2014
Lens-Free Microscopes Offer Real-Time Bio Imaging
A totally different type of microscope will be much smaller and less complex than traditional microscopes, but more powerful. Two years ago, a customer handed Richard Stahl and the imec team a challenge: one year to develop a microscope that could...
Photonics.com, September 2014
Light-Sheet Microscopy Advances Biological Study
Light-sheet microscopy is faster and less phototoxic than other fluorescence microscopy techniques, making it ideal for studying living organisms and the biological processes that take place within them. Fluorescence microscopy techniques have...
BioPhotonics, August 2014
Multispectral Quantitative Phase Imaging Captures Live Human Cells Quickly
Within biological systems, structural, chemical and functional information about a system of interest can be extracted from the wealth of spectral data available. This article focuses on the specific application of multispectral imaging to...
BioPhotonics, August 2014
Streamlined Lasers Enable Lower-Cost Instruments than LEDs
A comprehensive analysis reveals that lasers provide both superior performance and lower total cost in comparison with LEDs for life sciences instrumentation. Biotech instrumentation manufacturers are currently developing products that feature...
BioPhotonics, August 2014
The Promise of Advanced Laser-Based Therapy
Medical lasers are making rapid progress in numerous new applications including drug delivery, oncology, gene therapy, nerve repair and dentistry. It started with mouse hairs. In 1967, Dr. Endre Mester of Semmelweis Medical University in Budapest,...
BioPhotonics, August 2014
Moving Raman Spectroscopy into the Clinic
Raman spectroscopy’s molecular sensitivity makes it promising for clinical applications: It can identify pathogens much faster than current methods, investigate circulating tumor cells, help surgeons distinguish tumors from healthy tissue and...
Photonics.com, June 2014
Optodigital Microscopy Enhances Efficiency of Material Testing
Automated microscopes can help speed up the industrial quality-control process, saving time and money. Time is money when it comes to industrial work flows, and efficiency is a key priority. This is especially true with regard to one of the SGS...
Photonics.com, June 2014
Challenges Not Insurmountable for Terahertz Spectroscopy
Cost, size and power must be addressed before terahertz spectroscopy can broaden its commercial acceptance – but steps are being taken. Today, terahertz spectroscopy shows promise for some fascinating applications, from detecting illicit drugs...
BioPhotonics, June 2014
Microscopy Light Sources Illuminate Research Biology
Research biology is changing, moving toward more complex experiments that combine imaging and traditional fluorescence with photostimulation and electrophysiology. As these new directions evolve, they require light sources that adapt on the fly,...
BioPhotonics, June 2014
QCLs for Medicine: The Promise and the Payoff
Although hurdles remain, the promise of quantum cascade lasers in medicine moves closer to realization with the commercial introduction of a microscopy platform, demonstration of a prototype device for breath analysis, and continued research and...
BioPhotonics, June 2014
Photoacoustics Applications Expand Beyond Cancer
In March, the first article in this two-part series looked at the potential of photoacoustic technologies to revolutionize cancer detection. This second part will examine uses in diagnosing blood disorders, monitoring diabetes and more. Advances in...
BioPhotonics, June 2014
Lasers Produce Bio-Inspired Surface Functions
Lasers can interact with matter in a variety of ways. Depending on the wavelength, the energy of the laser beam and a whole set of other parameters, such as pulse duration or repetition rate, laser photons have countless ways of mingling with the...
Photonics.com, April 2014
FRET Pursues Affordable, Robust, User-Friendly Instruments
From single-molecule studies to in vivo imaging, FRET spectroscopy is a versatile and far-reaching tool. But further work needs to be done before the technique becomes more universally applicable. Although FRET (Förster resonance energy...
BioPhotonics, April 2014
Seeing the Light: How Photonics Continues to Improve Eyesight
Cutting-edge laser technology and new techniques are enabling amazing diagnostic and treatment advances in ophthalmology. In 1981, Rangaswamy “Sri” Srinivasan, a researcher at IBM’s Thomas J. Watson Research Center, experimented...
BioPhotonics, April 2014
Software Enhances Life Sciences Applications, Biomedical Simulations
Optomechanical design software helps develop efficient and effective biomedical product designs. The interdisciplinary nature of optical modeling for life sciences applications implies a high degree of collaboration among medical doctors, life...
BioPhotonics, April 2014
Superresolution Imaging Adds Another Dimension
3-D techniques advance a range of biological research studies. Conventional light microscopy is generally constrained by the diffraction limit, the fundamental maximum resolution of an optical imaging system resulting from the diffraction of light....
BioPhotonics, April 2014
Building the Perfect Fiber Optic Probe
Researchers face old-school challenges in developing state-of-the-art technologies. Researchers and clinicians use fiber optic-based probes for a wide range of applications – which means the probes must exhibit varying amounts of complexity....
BioPhotonics, March 2014
Making Strides in Fourier Transform Spectroscopy
Innovative techniques and improvements in instrumentation are expanding the potential of Fourier transform infrared spectroscopy in bio applications and many other fields. Fourier transform spectroscopy (FTS) allows researchers to acquire spectra of...
BioPhotonics, March 2014
Photoacoustics Holds Promise for Cancer
Diagnosis and monitoring of cancer are two of the top potential uses for PA technologies. This is the first of a two-part series that will look more closely at the work of the dedicated researchers making some of the most exciting recent (and...
BioPhotonics, March 2014
Ultrafast Laser Systems Are Stepping Up to Meet Industry Needs
Improvements in ultrafast lasers support superior surgical precision, take imaging deeper and help to unlock the secrets of the brain. With their unique ability to deliver high peak power without thermal damage, ultrafast lasers are ideally suited...
BioPhotonics, March 2014
sCMOS Cameras Examine Movements of Pathogens
Researchers seek side-effect-free treatment for African sleeping sickness, and fast imaging technology plays a vital role in the effort. It’s an age-old epidemic, and it’s terrifyingly deadly: African sleeping sickness, or...
Photonics.com, March 2014
Fast Camera Tracks Agile Survival Artists
Biologists use high-speed imaging to study how microorganisms move. Some like it hot – for example, micro-organisms that live in the deep sea on “black smokers,” where heat rises from the interior of the earth. These archaea, or...
BioPhotonics, February 2014
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