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Holotomography Unlocks New Potential for Life Sciences Research
3D holographic microscopy enables quantitative and noninvasive investigation of cells’ intrinsic properties — without labeling agents. Holotomography is now poised to advance disease diagnosis and treatment.
BioPhotonics, September 2016
Growing Gratings Menu a Boon for Biophotonics Research
An optical grating is an optical component with a periodic or quasi-periodic structure. Gratings perform interference of diffracted lights from each grating line to realize specific optical functions, such as the wavelength dispersion, polarization...
BioPhotonics, September 2016
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NIR and Optoacoustic Spectroscopy Cerebral Oximeters Aim to Save Preemies
In 1985, a team of researchers at Duke University Medical Center in Durham, N.C., pointed out the incongruity that, while the goal of intensive care for preterm newborns is to ensure their brains were receiving sufficient oxygen, neonatal intensive...
BioPhotonics, September 2016
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Tip-Enhanced Raman Spectroscopy Takes Bio Fingerprinting to Nanoscale Level
Despite being able to provide fingerprint information in biology, medicine and other fields, Raman spectroscopy suffers from a signal-to-noise ratio that is limited by the inherent weakness of Raman scattering and a spatial resolution that is...
BioPhotonics, September 2016
When the Camera Is a Computer: Computational Life Sciences Imaging
Sensors and cameras continue to progress, although life sciences imaging remains far from perfect. Even in its current state, barriers still exist. These include signal photon noise, light scattering, optical blur of finite aperture imaging systems...
BioPhotonics, August 2016
High-Content Screening Goes Beyond Fluorescent Pictures
Since the start of high-content screening (HCS) in the late 1990s, several imaging techniques have been applied for automated image capture, serving a variety of application goals and specifications. However, technological advancements are enabling...
BioPhotonics, August 2016
New Quantum Dots Excite In Vivo Imaging Advancements
New quantum dots made without heavy metals are poised to take optical in vivo imaging to the next level.
BioPhotonics, August 2016
Neuroscience Driving Continued Growth in Multiphoton Microscopy
More than half of the thousands of deployed multiphoton microscopes are used for neuroscience — in large part because of major funding initiatives across three continents. Some of these initiatives are specifically targeted toward in vivo...
BioPhotonics, August 2016
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OCT Angiography Opens Eyes
Dr. Daniela Ferrara, an assistant professor of ophthalmology at Tufts University School of Medicine in Boston, began researching retinal diseases in 1998. Age-related macular degeneration (AMD), a leading cause of blindness in elderly individuals of...
BioPhotonics, August 2016
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Life in the Ultrafast Lane with Fiber Lasers
For lasers, shorter pulses mean more precision and new applications. That’s been true for decades. What’s changed in the last few years is that prices for lasers with pulse widths a picosecond or less are dropping significantly. The...
Photonics.com, June 2016
Beyond OCT: New Interferometric Imaging Techniques in Biomedicine
Optical coherence tomography (OCT) began its commercial history in 1996 as a revolutionary technology for imaging retinas to help diagnose eye diseases, including glaucoma, macular degeneration and diabetic retinopathy. Now a mainstay in...
BioPhotonics, June 2016
Low-Level Light Therapy Is Still Looking for — and Finding — Clinical Inroads
The field of low-level light therapy (LLLT) emerged soon after the invention of the ruby and helium-neon (HeNe) lasers in the early 1960s. Since then, the technique has progressed, proving effective for a number of therapeutic areas, including...
BioPhotonics, June 2016
Procedures Hinge on Nonlaser Light Sources’ Optimal Spatial Intensity Distribution
Unsterilized medical products, dental restorations with incompletely cured restorative materials and adhesives that fail in their application are a few of the potential outcomes when light-based processes are poorly understood. Laser beam profiling...
BioPhotonics, June 2016
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Next-Generation Stereo Endoscopes are Opening Surgeons' Eyes
In its drive to explore outer space, NASA is developing optical technology that tests the limits of the laws of physics and promises to turn neurosurgeons into pioneers in innerspace. While minimally invasive neurosurgery is far from being the final...
BioPhotonics, June 2016
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SERS Spectroscopy Solves Outstanding Problems in the Biological Sciences
Raman spectroscopy is a spectroscopic technique used to measure vibrational transitions in molecules, yielding detailed information on molecular structures and their environments. Given that it is a light-scattering technique that uses a visible...
BioPhotonics, April 2016
Real-Time Volumetric 3D Imaging Technology
Multi-planar volumetric imaging systems, which produce 3D volume renderings from 2D projections, are finding a number of applications in aerospace and defense. However, the medical industry is particularly ripe for this technology because of the...
BioPhotonics, April 2016
Optical Tweezers Bring Major Discoveries Within Grasp
Optical tweezers offer a noninvasive experimental method to trap, track and manipulate microscopic objects ranging from several tens of micrometers to tens of nanometers in size. The trapped particles can be accurately measured and manipulated with...
BioPhotonics, April 2016
Drones with Multispectral Cameras Bring Efficiency to High-Throughput Plant Phenotyping
In 1866, the Brno Natural History Society, in what is now the Czech Republic, published an Austrian monk’s paper, “Experiments in Plant Hybridization,” which reviewed his observations of pea plants grown in a monastery garden....
BioPhotonics, April 2016
Advances in Laser Diodes Can Bring Portability to Point-of-Care Photoacoustic Systems
Photoacoustic imaging (PAI) has attracted much attention in recent years as a complementary technique to classical ultrasound and optical coherence tomography. This novel technique combines pulsed laser light for excitation of tissues with an...
BioPhotonics, March 2016
Using Photonic Components to Design and Build Life Science and Analytical Instruments
Life science and analytical instruments based on optical techniques have moved from university and corporate research laboratories, through central diagnostic and pathology laboratories, to local hospital laboratories. They are now becoming more and...
BioPhotonics, March 2016
Prism Awards Highlight Photonics Innovation
Avotec, Biodesy and Convergent Dental are among 27 finalists in nine categories for the 2016 Prism Awards for Photonics Innovation. The awards are sponsored by SPIE, the international society for optics and photonics, and Photonics Media. Winners...
BioPhotonics, January 2016
Top Biophotonics Stories of 2015
A pair of studies released last November indicate that the global biophotonics market hit its stride in 2015 and will significantly grow in size over the next five years. One of those studies, by Future Market Insights, predicted the global...
BioPhotonics, January 2016
Surgical Lasers Make the Cut
In surgery, the best cut is often the smallest. Because they enable precision targeting and can minimize tissue trauma, lasers offer an advantage in surgery. What’s more, they can deliver healing light, thereby widening treatment...
BioPhotonics, January 2016
Can Confocal Microscopes Compete with the Emergence of Superresolution?
Like most things, confocal microscopes have improved with age. The technique dates back to 1955, when American cognitive scientist Professor Marvin Minsky proposed that the ideal microscope would eliminate all light rays not initially aimed at the...
BioPhotonics, January 2016
Spectroscopy Can Head Off Food Safety Crises
Consumers expect that the food they purchase has been checked for potential health hazards. In today’s hyper-connected world, it’s becoming more important for a company to ensure the products it sends to market are safe, avoiding alarm...
BioPhotonics, December 2015
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