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Optical Filters Help PCR Tests Quickly Diagnose COVID-19
The need to implement technology that can rapidly diagnose diseases and pathogens accurately has never been greater than it is now, as the COVID-19 virus continues to spread around the world. Prior to 2020, most people working outside the field of molecular biology would not have been aware of polymerase chain reaction (PCR) testing and its ability to amplify the presence of biomarkers to enable the optical detection and identification of genetic material from specific organisms, such as...
BioPhotonics, Jan/Feb 2022
Multiphoton Exoscope Broadens Noninvasive Imaging of Skin
Skin imaging at the cellular level is critical for understanding how diseases and aging affect the skin, and for developing strategies and therapies to prevent and combat these effects in a clinical setting. Visualizing dynamic cellular and...
BioPhotonics, Jan/Feb 2022
Miniaturization in NIR Spectroscopy Reshapes Chemical Analysis
Near-infrared (NIR) spectroscopy has been used in groundbreaking research in many of the life sciences due to its capacity to rapidly determine and analyze the composition of materials. Bulky instruments with limited portability, however, have kept...
BioPhotonics, Jan/Feb 2022
The Hyperspectral Camera Looks Alzheimer’s in the Eyes
Alzheimer’s disease is one of three so-called trillion-dollar diseases, along with cancer and diabetes — meaning that financial and societal costs are approaching $1 trillion worldwide. Diagnosis has historically been a complex task, requiring...
BioPhotonics, Jan/Feb 2022
Laser Therapy Reaches Hard-to-Treat Epilepsy
For decades, the most commonly used treatments for epilepsy were pharmaceuticals or resection surgery, which involves removing a segment of brain tissue from where the patient’s seizures originate. These remedies can work well and continue to be the...
BioPhotonics, Nov/Dec 2021
Neurophotonic Techniques Shed New Light on Traumatic Brain Injury
Traumatic brain injury can have catastrophic impacts on everyday functioning and quality of life. Now, a set of photonic tools may provide fresh insights into this condition. Along with the technical knowledge made available by the application of...
BioPhotonics, Nov/Dec 2021
Biomedical Research, Innovation to Take Center Stage at SPIE BiOS
A rapid-fire Hot Topics session featuring talks on the latest in biomedical optics, from live analysis of embryonic development to deep learning-enabled optics, will be a centerpiece at SPIE BiOS — part of Photonics West 2022 — to be...
BioPhotonics, Nov/Dec 2021
Two-Photon Imaging Monitors Brain Synapses During Prolonged Anesthesia
The formation of synapses in the circuitry of the brain, and especially the solidification and disappearance of synaptic structures, mediates how people learn, memorize, and forget. Since the introduction of two-photon imaging to neuroscience in the...
BioPhotonics, Nov/Dec 2021
Fluorescence Lifetime Imaging Reveals the Cutting Edge in Cancer Surgery
Fluorescence lifetime imaging (FLIm) is an optical spectroscopic technique that is well suited to interrogating biological tissues in vivo. By measuring the time-resolved fluorescence properties intrinsic to tissues, FLIm can distinguish between...
BioPhotonics, Nov/Dec 2021
NIR Spectroscopy Captures the Impacts of Stroke
Every year, approximately 5.5 million people worldwide lose their lives to stroke. According to the Centers for Disease Control and Prevention, stroke-related costs in the U.S. total nearly $50 billion annually. Stroke is the fifth leading cause of...
BioPhotonics, Nov/Dec 2021
The BioPhotonics Conference
Photonics Media will host the first-ever BioPhotonics Conference online Oct. 26-28. Experts in microscopy, spectroscopy, OCT, flow cytometry, and medical lasers will present on topics such as the detection of cancer and viruses, the analysis of...
BioPhotonics, Sep/Oct 2021
Spectroscopic Tools Facilitate Bedside Diagnosis
Numerous research studies over the past two decades have attested to the promise that spectroscopy holds for diagnosing disease and for guiding therapy in real time. Yet, despite the remarkable advancements that have been made in photonic technology...
BioPhotonics, Sep/Oct 2021
Plasmonic Tip Detects Viruses’ Raman Signal
Scientists and health experts searching for a tool that will help in the diagnosis of COVID-19 today as well as prepare for the pandemics of tomorrow may soon find a solution in a suite of techniques based on the Raman effect. Raman spectroscopy...
BioPhotonics, Sep/Oct 2021
Camera Optimization Helps to Clarify In Vivo Diagnosis and Plan Treatment
Pre-clinical in vivo studies are essential to our understanding of human disease, as well as to the development and administration of new treatments and therapeutic agents. Noninvasive, pre- clinical, in vivo imaging techniques allow for long-term...
BioPhotonics, Sep/Oct 2021
NIR Fluorescence Captures Clear Images of Cancerous Tumors During Surgery
Despite discoveries made in cancer research in recent years, few new techniques have significantly changed the course of the disease, which is responsible for more than 25,000 deaths in the U.S. every day. Surgery is usually the most effective...
BioPhotonics, Sep/Oct 2021
OCT Presents Multidimensional Imaging for Diagnosis and Detection
Optical coherence tomography (OCT) is a noninvasive imaging technique that is used to deliver high-resolution images in two or three dimensions. It relies on the wave-like properties of light to produce a low- coherence interference spectrum. In...
BioPhotonics, Jul/Aug 2021
Smart Probe Captures Biomarker Sequence
A smart probe is a hairpin oligonucleotide, essentially a string of nucleic acids, that is labeled with a fluorophore on one end and tethered with successive guanosine residues on the other end. Extrinsic dye labels with suitable absorption are...
BioPhotonics, May/Jun 2021
Plasmonics and Microfluidics Speed Detection of Lyme Disease
When a person develops Lyme disease from a tick bite, identifying the tiny culprit can be challenging. The insect itself is difficult to see in the grass or forested area it comes from before burrowing into the person’s skin. The symptoms of...
BioPhotonics, May/Jun 2021
Liquid Crystal Sensors Provide Rapid COVID-19 Diagnosis
The global outbreak of COVID-19 has prompted scientists worldwide to focus their research on the virus over the last year, particularly those who work with optical and sensing technologies. Some have concentrated on understanding fundamental aspects...
BioPhotonics, Jul/Aug 2021
Charge Clusters in a Monomeric Protein Alter Optical Absorption
Electronic absorption of proteins that lack cofactors, prosthetic groups, or noncoded amino acids as part of their structure has traditionally been thought to originate from protein backbone (peptide bond) and aromatic chromophores in the side...
BioPhotonics, Jul/Aug 2021
Quantum Cascade Lasers Boost Life Science Research
Over 20 years have passed since the first quantum cascade laser (QCL) sources were commercialized. QCLs that operate at room temperature using thermoelectric cooling are now ubiquitous. These lasers ushered in a new era of infrared spectroscopy. In...
BioPhotonics, Jul/Aug 2021
ASLMS 2021 Examines Laser-Based Treatments, Diagnosis in Online Setting
Following the cancellation of last year’s event, this year’s conference of the American Society for Laser Medicine and Surgery (ASLMS) will rebound with a virtual presentation of the latest in laser-based science and research. Registration is open...
BioPhotonics, Mar/Apr 2021
Microscopy Technique Enhances 3D Imaging Capability
Optical microscopes use light to visualize detailed structures of small samples. The most popular microscopy technique for biological or biomedical studies by far is wide-field microscopy, in which a sample, such as tissue, is imaged through a...
BioPhotonics, Mar/Apr 2021
Diode Array Spectrometers Augment Fluorescence-Based Research
Fluorescence spectroscopy is an established method for detecting concentrations of biological material in medicine or in environmental analysis. The key benefit of using fluorescence over other techniques of spectral analysis such as UV absorbance...
BioPhotonics, Mar/Apr 2021
Eye Care, Laser Technology, and Imaging Modules Among 2021 Prism Award Finalists
Six biophotonics technologies that enhance retinal imaging, disease diagnosis, and surgical precision are among the 30 finalists SPIE has selected for this year’s Prism Awards. Winners in 10 categories will be announced as part of the SPIE...
BioPhotonics, Jan/Feb 2021
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