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Features
Moving Raman Spectroscopy into the Clinic
Raman spectroscopy’s molecular sensitivity makes it promising for clinical applications: It can identify pathogens much faster than current methods, investigate circulating tumor cells, help surgeons distinguish tumors from healthy tissue and identify the chemical nature of cardiovascular plaques and evaluate their severity. Today’s aging population presents a great challenge: ensuring affordable and sustainable health care systems. As the number of people over 65 grows, society
Photonics.com, June 2014
Optodigital Microscopy Enhances Efficiency of Material Testing
Automated microscopes can help speed up the industrial quality-control process, saving time and money. Time is money when it comes to industrial work flows, and efficiency is a key priority. This is especially true with regard to one of the SGS...
Photonics.com, June 2014
Challenges Not Insurmountable for Terahertz Spectroscopy
Cost, size and power must be addressed before terahertz spectroscopy can broaden its commercial acceptance – but steps are being taken. Today, terahertz spectroscopy shows promise for some fascinating applications, from detecting illicit drugs...
BioPhotonics, June 2014
Microscopy Light Sources Illuminate Research Biology
Research biology is changing, moving toward more complex experiments that combine imaging and traditional fluorescence with photostimulation and electrophysiology. As these new directions evolve, they require light sources that adapt on the fly,...
BioPhotonics, June 2014
QCLs for Medicine: The Promise and the Payoff
Although hurdles remain, the promise of quantum cascade lasers in medicine moves closer to realization with the commercial introduction of a microscopy platform, demonstration of a prototype device for breath analysis, and continued research and...
BioPhotonics, June 2014
Photoacoustics Applications Expand Beyond Cancer
In March, the first article in this two-part series looked at the potential of photoacoustic technologies to revolutionize cancer detection. This second part will examine uses in diagnosing blood disorders, monitoring diabetes and more. Advances in...
BioPhotonics, June 2014
Lasers Produce Bio-Inspired Surface Functions
Lasers can interact with matter in a variety of ways. Depending on the wavelength, the energy of the laser beam and a whole set of other parameters, such as pulse duration or repetition rate, laser photons have countless ways of mingling with the...
Photonics.com, April 2014
FRET Pursues Affordable, Robust, User-Friendly Instruments
From single-molecule studies to in vivo imaging, FRET spectroscopy is a versatile and far-reaching tool. But further work needs to be done before the technique becomes more universally applicable. Although FRET (Förster resonance energy...
BioPhotonics, April 2014
Seeing the Light: How Photonics Continues to Improve Eyesight
Cutting-edge laser technology and new techniques are enabling amazing diagnostic and treatment advances in ophthalmology. In 1981, Rangaswamy “Sri” Srinivasan, a researcher at IBM’s Thomas J. Watson Research Center, experimented...
BioPhotonics, April 2014
Software Enhances Life Sciences Applications, Biomedical Simulations
Optomechanical design software helps develop efficient and effective biomedical product designs. The interdisciplinary nature of optical modeling for life sciences applications implies a high degree of collaboration among medical doctors, life...
BioPhotonics, April 2014
Superresolution Imaging Adds Another Dimension
3-D techniques advance a range of biological research studies. Conventional light microscopy is generally constrained by the diffraction limit, the fundamental maximum resolution of an optical imaging system resulting from the diffraction of light....
BioPhotonics, April 2014
Building the Perfect Fiber Optic Probe
Researchers face old-school challenges in developing state-of-the-art technologies. Researchers and clinicians use fiber optic-based probes for a wide range of applications – which means the probes must exhibit varying amounts of complexity....
BioPhotonics, March 2014
Making Strides in Fourier Transform Spectroscopy
Innovative techniques and improvements in instrumentation are expanding the potential of Fourier transform infrared spectroscopy in bio applications and many other fields. Fourier transform spectroscopy (FTS) allows researchers to acquire spectra of...
BioPhotonics, March 2014
Photoacoustics Holds Promise for Cancer
Diagnosis and monitoring of cancer are two of the top potential uses for PA technologies. This is the first of a two-part series that will look more closely at the work of the dedicated researchers making some of the most exciting recent (and...
BioPhotonics, March 2014
Ultrafast Laser Systems Are Stepping Up to Meet Industry Needs
Improvements in ultrafast lasers support superior surgical precision, take imaging deeper and help to unlock the secrets of the brain. With their unique ability to deliver high peak power without thermal damage, ultrafast lasers are ideally suited...
BioPhotonics, March 2014
sCMOS Cameras Examine Movements of Pathogens
Researchers seek side-effect-free treatment for African sleeping sickness, and fast imaging technology plays a vital role in the effort. It’s an age-old epidemic, and it’s terrifyingly deadly: African sleeping sickness, or...
Photonics.com, March 2014
Fast Camera Tracks Agile Survival Artists
Biologists use high-speed imaging to study how microorganisms move. Some like it hot – for example, micro-organisms that live in the deep sea on “black smokers,” where heat rises from the interior of the earth. These archaea, or...
BioPhotonics, February 2014
Raman Technique Offers Promise for Clinical Applications
Intraoperative imaging of brain tumors is among the potential uses that could benefit from Raman imaging. Raman imaging has been explored for a range of uses; among the most exciting of these are applications in the biomedical arena. Here,...
BioPhotonics, February 2014
SERS on the Verge of Diagnostic Success
Surface-enhanced Raman spectroscopy is the emerging star of Raman spectroscopy, promising the ultimate in sensitivity, early disease diagnosis and more. After years of exclusion as an academic technique, Raman spectroscopy has finally, firmly taken...
BioPhotonics, February 2014
Simplified Approach Makes Two-Photon Multicolor Imaging Less Costly
A fixed-wavelength laser in combination with a nondescanned hyperspectral detection system obtains clean images when used with triple-stained samples with all dyes excited simultaneously. Two-photon microscopy (TPM) is the method of choice for...
BioPhotonics, February 2014
Challenges to CARS Microscopy: Light at the End of the Tunnel
Coherent anti-Stokes Raman scattering (CARS) microscopy historically has struggled to break into a marketplace already crowded with popular imaging techniques such as fluorescence microscopy and with new superresolution techniques such as STORM...
BioPhotonics, January 2014
Looking Down the Endoscope
Confocal microscopy techniques advance the monitoring of Barrett’s esophagus and other applications. Barrett’s esophagus – a condition in which the cells lining the esophagus are replaced by cells similar to those found in the...
BioPhotonics, January 2014
Magnification Fluoroscopy Technique Drives Advances in Clinical Studies
Thin-film CsI:Tl coatings offer real-time high-resolution video, enabling discoveries in medical research trials. Advances in x-ray imaging techniques are bringing benefits to in vivo imaging applications. One such advance is LabScope, a...
BioPhotonics, January 2014
Molecular Spectroscopy Illuminates Life-Governing Systems
Simple, fast and particularly cheap – is it any wonder that molecular spectroscopy is quickly becoming one of the most common tools in the laboratory? Molecular spectroscopy is photonics at its most fundamental: the interaction between light...
BioPhotonics, January 2014
OCT Technologies, Applications Showing Great Promise
A panel of industry experts weighs in on recent and future advances in optical coherence tomography, and offers a look at the market. OCT is growing. As we reported in the July issue, the optical imaging market is set to reach $1.9 billion by the...
BioPhotonics, January 2014
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