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Focus-Tunable Lenses Enable 3-D Microscopy
Focus-tunable lenses speed up and enhance three-dimensional imaging capabilities in a diverse set of modern microscopy methods including confocal, two-photon and light-sheet microscopy. Microscopy beginners may be perplexed when they notice that parts of a sample that appear only marginally out of focus often look much more blurred in an image. The depth of field as seen by the human eye seems to be considerably larger than the depth of field seen by a camera. This bewildering effect
BioPhotonics, April 2015
Lasers for Microscopy: Major Trends
Laser development for the microscopy market continues to be driven by key trends in applications, which currently include superresolution techniques, multiphoton applications in optogenetics and other areas of neuroscience, and even a shift in...
BioPhotonics, April 2015
Femtosecond Lasers Provide a Gentler Way to Micromachine
From the unbreakably hard to the vulnerably soft – from glass, metals and ceramics to plastics and biological tissue – femtosecond lasers are being increasingly adopted for micromachining a range of materials. Femtosecond lasers are...
Photonics.com, March 2015
Lasers, Optics Enhance Optogenetics Studies
A guide to suitable light sources and fiber optic components for optogenetics research, with a specific emphasis on rodent behavior. The use of lasers and optics for optogenetics is only in its infancy. In the next decade, we can expect researchers...
Photonics.com, March 2015
Diverse Applications Drive Lasers for Multiphoton Microscopy
After years of domination by a single ultrafast laser technology (Ti:S) and its associated add-ons, laser manufacturers have broadened their technology portfolios to better support a diversified and dynamic nonlinear imaging applications space.
BioPhotonics, March 2015
Raman Spectroscopy and Microscopy Enable Life Science Discoveries
The first article in this two-part series looked at Raman spectroscopy applications in tumor surgery, endoscopy and bacterial identification. This second part examines applications in cell sorting, laser trapping, biology probing and more.
BioPhotonics, March 2015
Lens-Free Microscopy Goes Scalable
A compact lens-free microscope could replace microscopes – and even expand their use – in a number of key biomedical applications, such as stem-cell culturing or in vitro drug testing. Using photonic integration, the microscope can even...
BioPhotonics, March 2015
Multiphoton Imaging Takes New Directions
Recent evolutions of ultrafast laser technology uniquely overcome key challenges in bioimaging, especially for long-term in vivo imaging, deep penetration and leveraging multimodal imaging strategies. Since the early 1990s – and even more so...
BioPhotonics, March 2015
Lasers, Optics Enhance Optogenetics Studies
A guide to suitable light sources and fiber optic components for optogenetics research, with a specific emphasis on rodent behavior. The use of lasers and optics for optogenetics is only in its infancy. In the next decade, we can expect researchers...
BioPhotonics, January 2015
Line-Narrowed Laser Module Enables Spin-Exchange Optical Pumping
The optical technique enhances MRI technology for diagnosis and other applications. In the past several decades, medical imaging has made huge strides. The field of MRI in particular has seen huge advancements in technical capability, as recognized...
BioPhotonics, January 2015
Microspectroscopy Enables Real-Time Imaging of Singlet Oxygen
A new experimental setup allows researchers to monitor a highly reactive species of molecular oxygen that plays an important role in a wide range of biological processes. Oxygen is one of the most important molecules in maintaining life, as well as...
BioPhotonics, January 2015
Raman Spectroscopy and Microscopy: Solving Outstanding Problems in the Life Sciences
This first article in a two-part series will examine Raman spectroscopy applications in tumor surgery, endoscopy, bacterial identification and more. The second part will cover applications in cell sorting, laser trapping and probing biology. Raman...
BioPhotonics, January 2015
Selecting a Microscope Based on Imaging Depth
Optical microscopy has advanced greatly over the past decade. Here’s how to select the right instrument for any particular application. Selecting the right optical microscopy system relies on a variety of factors: whether the instrument will...
BioPhotonics, January 2015
Photonics Innovators Named 2015 Prism Awards Finalists
Finalists include tools for 3-D printing, water analysis and laser-engineered surfaces. Innovative products, inventions and companies will take center stage Feb. 11, as the winners of the 2015 Prism Awards for Photonics Innovation are honored during...
Photonics Spectra, January 2015
Collaboration Advances Intraoperative Assessment of Tumor Margins
Physicians, companies come together to address clinical translation issues. It’s a long-standing truth: For the biophotonics community to meet the needs and constraints of the medical field and to translate technological advances for clinical...
BioPhotonics, December 2014
Global-Shutter vs. Rolling-Shutter Readouts
New sCMOS cameras overcome rolling-shutter artifacts by combining the best of both global and rolling shutters to achieve the simultaneous exposure with all rows, all while maintaining the frame rate and low noise benefits of rolling-shutter...
BioPhotonics, December 2014
STED Microscopy Made Easy
Stimulated emission depletion microscopy surpasses diffraction-limited microscopy by offering much more information about structures. Combining STED with time-tagged data acquisition methods makes even more information available. With fluorescence...
BioPhotonics, December 2014
Top Biophotonics Stories of 2014
QCL-based glucose testing, hyperspectral imaging and molecular techniques lead the list of the year's most popular stories.
BioPhotonics, December 2014
Printed Optics Usher in New Era of Manufacturing
Additive manufacturing techniques are set to revolutionize fabrication and integration of optical products for a variety of applications, from lighting to imaging and beyond. Additive manufacturing techniques are creating a new awakening in optics...
Photonics.com, December 2014
Imaging At The Speed Of Life
On the road to ultrafast imaging, bottlenecks include both hardware and software – but researchers are working to overcome these challenges. Being able to take a faster snapshot could benefit bio researchers – and the rest of us, too....
BioPhotonics, November 2014
Laser Combiner Enables Scanning Fluorescence Endoscopy
A laser-scanning fiber endoscope uses a plug-and-play laser combiner to enable high-contrast images suitable for detecting early-stage precancerous lesions. Detection of early cancerous lesions using molecular imaging can improve disease diagnosis...
BioPhotonics, November 2014
Multispectral Sensor Boosts Molecular Diagnostics
A new low-cost multispectral fluorescence detection sensor helps overcome barriers to using molecular diagnostics in point-of-care testing. In molecular diagnostics, fluorescent probes are used for detection of specific genetic material associated...
BioPhotonics, November 2014
UV-VIS Spectroscopy in the Clinic – What’s Stopping It?
The technique has been around for years and shows great promise, but so far researchers have been frustrated in their attempts at clinical translation. Imaging techniques using UV-VIS spectroscopy hold promise for a range of important clinical...
BioPhotonics, November 2014
Shorter Wavelengths, Pulses Power Laser Manufacturing
Recent laser advances are bringing benefits to manufacturing applications involving drilling, cutting and welding. More powerful diode lasers could, in the future, do more of these jobs directly, instead of being used to pump another material. The...
Photonics.com, October 2014
Color Management Helps Microscopy Show Its True Colors
Establishing a standard could allow microscopists to verify and reproduce results. Laboratory managers and researchers generally agree that having more accuracy and consistency in color rendition could assist in achieving improved evaluation of...
BioPhotonics, October 2014
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