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BioPhotonics - Mar/Apr 2024


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Features
Raman Spectroscopy Probes the Etiology of Amyloidogenic Disease The urgent need for rationally designed treatments of Alzheimer’s disease and other amyloidogenic disorders is more relevant than ever; there is a predicted 7% increase of cases of Alzheimer’s by 2025 in people aged 65 and older, according to the Alzheimer’s Association. Several lines of evidence suggest that amyloid-ß (Aß) fibril structure is intimately linked to the pathophysiological features,...
Making the Photon Count in Confocal Microscopy When used appropriately, a laser scanning confocal fluorescence microscope is a valuable tool for researchers to make quantitative measurements in cells and tissue across various life sciences...
Bringing Laser Speckle Imaging to the Point of Care While laser speckle contrast imaging (LSCI) has historically been confined to a bulky benchtop configuration, multiple research teams have recently developed hand-held and wearable laser speckle...
Single Fiber Endoscopy Records Neural and Vascular Detail The growing incidence of chronic diseases around the world has driven the expansion of techniques to provide diagnosis at the source, which would ideally involve a minimally invasive — but...
SPIE Names 2024 Prism Award Winners SPIE, the international society for optics and photonics, recognized the top innovations in new optics and photonics products at the 2024 Prism Awards held at Photonics West on Jan. 31. The gala...
Editorial
Fiber plots a focused diagnostic path When ancestors of modern endoscopy first peered into cavities of the human body, they used candlelight or burned a mixture of alcohol and turpentine, which illuminated a thin tube equipped with a lens. In the 19th century, the French inventor Antonin Jean Desormeaux, who is regarded as the father of endoscopy, used such a device to guide chemical cauterization, a simple and painful procedure in...
BioScan
PlaqueTec, Babraham Institute collaborate on blood screening Biotechnology company PlaqueTec and the Babraham Institute’s Flow Cytometry Facility have begun a collaboration to develop cell phenotyping assay to detect cell subpopulations in human blood. The collaboration aims to use the assay to investigate the different cell types present in coronary artery samples collected from patients with coronary artery disease (CAD) participating in...
Machine Learning Hones Ability to Image Liver Disease A research team at the Tokyo University of Science (TUS) has combined NIR hyperspectral imaging (NIR-HSI) and machine learning to assess lipid content in the liver. The technique enables noninvasive...
AI-aided Implant Captures Deep Brain Images A neural implant developed at the University of California San Diego could help advance the path to minimally invasive brain-computer interface (BCI) technology. The implant provides high-resolution...
Raman Approach Safely Tracks Live-Cell RNA Expression Single-cell RNA sequencing enables scientists to interrogate cells at extraordinary resolution and scale. However, the sequencing process destroys the cell, making it difficult to use the technique...
Oxford Instruments Acquires First Light Imaging Oxford Instruments has acquired specialist camera provider First Light Imaging. Following the acquisition, the company will become part of Oxford Instruments Andor, complementing the company’s...
Optical-Plasmonic SERS Platform Clocks Molecular Systems An optical plasmonic tweezer-controlled surface-enhanced Raman spectroscopy (SERS) platform developed by Hong Kong University of Science and Technology (HKUST) enables efficient, high-throughput,...
Excelitas to Relocate Headquarters to Pennsylvania Excelitas Technologies will relocate its operations to Pittsburgh, moving from its current headquarters in Waltham, Mass., outside of Boston. According to a release issued by Pennsylvania. Gov. Josh...
Bruker Continues Expansion, Acquiring Seven Companies In separate transactions, Bruker Corporation has entered into agreements to acquire in vitro diagnostics manufacturer ELITechGroup (ELITech), as well as cell imaging company Phasefocus. The...
Optoacoustics, AI Monitor Disease in Patients With Diabetics One complication of diabetes is microangiopathy, a condition affecting the microvascaulature, which affects numerous organs, including the skin. Routine examinations of the skin’s...
3 Questions
3 Questions with Eric Diebold BioPhotonics spoke with Eric Diebold, worldwide vice president of research and development at BD Biosciences, who leads product and technology development for the biosciences business unit within Becton Dickinson. He received his Bachelor of Science degree in electrical engineering and physics from Duke University and his Ph.D. in applied physics from Harvard University. He spoke to us about the...
BioOpinion
Strong Standards Needed for Metrology and Raman Analysis Raman analysis faces several obstacles in meeting objective regulatory requirements — such as the lack of traceable quantification methods and absence of certified reference materials — which prevents its widespread use. Raman spectroscopy does not have an underlying metrological infrastructure, such as standardization allowing measurements to be linked to a quantity in the...
Postscripts
Researchers tattoo nanotech to live cells For some, tattoos are an expression of freedom: a piece of body art that will either prove to be a cool investment or a terrible regret once one realizes that the writing permanently etched into their skin reads “born to be mild” instead of “born to be wild.” But while tattoos are intended to enhance the wearer’s image in some way, in the research laboratory,...
Products
Laser Engine Modules The ML6600 from Modulight is a compact laser solution platform featuring customizable options including a specialized laser engine for flow cytometry, and distributed Bragg reflector (DBR) and...
Modulight Inc.
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UV LEDs The WC2X2C40L6-325 and WC2X2C40L9-340-V1 from Violumas are UV LEDs made for biological applications such as biological analysis, spectroscopy, and sensing. Producing wavelengths of 325 nm and 340 nm,...
Violumas Inc.
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Red Microscopy Laser The OBIS 640 XT from Coherent Corp. is a red diode-pumped solid-state laser module for super-resolution microscopy. With a maximum 1000-mW output at 640 nm, the module includes integrated control...
Coherent Corp.
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Reagent Cocktail Preparation System The Cytek Orion™ from Cytek Biosciences is an automated reagent cocktail preparation system for flow cytometry that eliminates the need for technicians to manually prepare multicolor antibody...
Cytek Biosciences Inc.
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Superresolution SIM Microscopes The Lattice SIM 3 and Lattice SIM 5 from ZEISS are superresolution microscopes that use structured illumination microscopy (SIM) to overcome the physical resolution limits of light microscopy. Along...
Carl Zeiss Microscopy GmbH, Microscopy
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Macro Mass Photometry Platform The KaritroMP from Refeyn is a macro mass photometry platform that can inform the research and development of gene and cell therapies and vaccines. The benchtop instrument allows for the...
Refeyn Ltd.
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Bragg Grating Notch Filters The WSF series from TeraXion comprises all-fiber band-stop (notch) filters that are used to selectively attenuate or block a wavelength or a range of wavelengths while allowing others to pass...
TeraXion Inc.
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Multi-LED for Wearables The SFH 7018 is a red/green/IR LED package from ams OSRAM that can make photoplethysmography (PPG) measurements in smart watches, wristbands, and other wearable devices. The multi-LED package uses a...
ams OSRAM
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Ophthalmic Microscope The Proveo 8 from Leica Microsystems is an ophthalmic microscope with an integrated EnFocus intraoperative OCT. The integration results in a 40% reduction in stack height — from 60 to 36 mm....
Leica Microsystems GmbH
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Microplate Wells The series of wells that have been added to ibidi’s µ-Plates include an expansion to its µ-Plate 96 Well to include both square and round shapes. The plates are available in 24, 96,...
ibidi GmbH
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Light Engine The ZIVA Light Engine from Lumencor was made for structured illumination microscopy, stochastic optical reconstruction microscopy, and other super-resolution microscopy applications. The engine...
Lumencor Inc.
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Long-Exposure Camera The Retiga E9 from Teledyne Photometrics is a long exposure camera that can capture exposures from tens of microseconds to tens of minutes. Featuring stacked CMOS sensor technology developed by Sony,...
Teledyne Photometrics
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Laser Microdissection System The Accuva Cellect from Laxco Inc. is a laser capture microdissection (LCM) system designed to enable isolation and capture of single cells with accuracy for improving research and analysis. The LCM...
Laxco Inc.
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Spectroscopy Module trinamiX in collaboration with LUMILEDS and VIAVI has developed a miniaturized spectroscopy module that can be integrated into a smartphone. The near-infrared (NIR) spectroscopy module runs on...
trinamiX GmbH
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