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BioPhotonics - Nov/Dec 2025
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Issue Library
Digital Edition
Features
Fluorescence Lifetime Imaging Microscopy Provides Molecular Insights in Neurology
Fluorescence lifetime imaging microscopy (FLIM) is rapidly becoming a transformative tool in neurology, enabling the visualization of molecular and metabolic processes in living brain tissue and...
Functional Near-Infrared Spectroscopy Targets Changes in Brain Metabolism
Functional near-infrared spectroscopy (fNIRS) was once confined to stationary, wired systems that limited studies to controlled laboratory environments. But today’s devices using this...
Multiphoton Microscopy Provides a Deeper View of the Aging Brain
Because deep-brain structures are key to how the nervous system communicates and maintains healthy function, understanding them is crucial for studying neurovascular dynamics, age-related changes,...
Fiber Optics Clarifies the View of Neural Activity
Optical fiber was once relegated to simple light delivery and collection in medical instruments, often for exploratory procedures. Today, this fiber winds its way into all manner of instrumentation...
Editorial
Clues from the feline brain
Many scientists rely on mice as test subjects to examine the biological symptoms of dementia, particularly mice genetically altered to develop the condition in their brains. But cats can also develop dementia spontaneously during their lives and experience the same buildup of amyloid plaques in their brains as humans with Alzheimer’s disease. A team at the University of Edinburgh recently...
Show Preview
SPIE BiOS Highlights Biomedical Discoveries and System Innovation
Innovations in single-molecule imaging for early disease identification and the advanced use of femtosecond lasers for spectroscopic analysis of samples will converge with discussions on early child development and DNA tracking at the SPIE BiOS symposium, which will open the proceedings of Photonics West 2026. Conference presentations, industry talks, panel discussions, poster sessions, and...
BioScan
Microscopy Connects Hypoxia in Brain to Stalled Blood Flow
Using high-resolution imaging with two-photon phosphorescent lifetime microscopy (2PLM), researchers learned that even brief interruptions in blood flow to capillaries in the brain can cause rapid,...
Breath-Activated Sensor Diagnoses Diabetes Rapidly
Due to a recent breakthrough, diabetes diagnoses will skip the lengthy lab work and doctor’s visits with a simple breath test. Researchers at Penn State University developed a sensor that can...
Exosens Continues Growth with Phasics Acquisition
Imaging and detection solutions developer Exosens will acquire wavefront sensing technology company Phasics. The deal expands Exosens' portfolio of offerings targeting defense, industrial control,...
Multifocus Microscope Pushes Limits of 3D Imaging
A high-speed 3D imaging microscope developed by researchers at the University of California, Santa Cruz can capture detailed cell dynamics of an entire small whole organism at once. The ability to...
Fluence Technology Secures $7.7M Investment
Fluence Technology, a developer of femtosecond fiber lasers, has secured PLN 28 million (approximately $7.7 million) in investments. The funds will support further development in the industrial,...
Microscopy Method Monitors Deep-Brain Metabolic Changes
A microscopy system developed by researchers at MIT addresses the challenges of using all-optical imaging techniques to visualize metabolic changes and neuronal activity deep within the brain. Using...
Evident Acquires Pramana for Autonomous Imaging
Evident has agreed to acquire Pramana, a manufacturer of digital pathology solutions for an undisclosed sum. Founded in 2021, Pramana is a developer of fully autonomous image scanning systems for...
OCT Technique Enhances Brain-Stimulation Mapping
Deep brain stimulation (DBS), a surgical procedure used to treat Parkinson’s, OCD, and other neurological disorders, involves implanting electrodes in specific brain regions to regulate...
Hypervision, imec Collaborate on Hyperspectral Imaging
Hypervision, a spin-out company formed from King’s College London that aims to advance computer-assisted tissue analysis for improved surgical precision and patient safety, is working to scale...
‘Self-Driving’ Microscope Predicts Neurodegeneration
The accumulation of misfolded proteins in the brain is central to the progression of neurodegenerative diseases like Huntington’s, Alzheimer’s, and Parkinson’s. But to the human...
3 Questions
3 Questions with René Heine
BioPhotonics spoke with René Heine, cofounder and CEO of Cubert, which specializes in real-time spectral imaging. The company has worked with researchers on using a novel diagnostic approach that combines snapshot hyperspectral imaging with artificial intelligence (AI) to detect spectral signatures associated with Alzheimer’s disease pathology in the retina. Some current methods for...
BioOpinion
Bringing Light to the Gut-Brain Axis
Functional optical imaging has made remarkable strides in neuroscience. Techniques such as calcium imaging have illuminated the dynamics of live brain activity, while optogenetics enables the precise control of neural circuits in freely moving animals. Functional near-infrared spectroscopy (fNIRS) allows noninvasive monitoring of neural activity in humans. Gaps remain, however, in our...
Postscripts
Brains can tell why sports fans yell
Courtesy of iStock.com. Gripping their seats during a sports match, passionate fans raucously cheer. This not only registers in the ears of those in the arena or living room but also creates a unique signature in the individual’s brain. Research from the University of Waterloo, using functional near-infrared spectroscopy (fNIRS), found that sports fans show different brain activity from...
Products
Square-Core Laser Cables
FlexiRay square-core silica laser cables from art photonics are designed for applications that demand a more specialized solution for beam shaping and power distribution compared to traditional round-core fibers. The square core produces a uniform beam profile which is needed for applications requiring consistent energy density. Compared to round-core fibers, power transfer from diode lasers and...
art photonics GmbH
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Bandpass Filters
BP610 optical bandpass filters from Midwest Optical Systems are designed for use in aquatic and agricultural environments. The BP610 product(s) features StablEDGE technology to minimize angular...
Midwest Optical Systems Inc. (MidOpt)
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Bioimaging Platform
Q-View Imager Plus from Quansys Biosciences is an imaging device designed to deliver reproducible, high-resolution ELISA results with streamlined workflows. Paired with Q-View Software, the platform...
Quansys Biosciences Inc.
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Microspectrophotometer
Azure Dragon™ UV-visible-NIR microspectrophotometer from Minerva Engineering is designed to nondestructively analyze many types of microscopic samples from the deep ultraviolet to the NIR....
Minerva Engineering Co. Ltd.
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High-Speed Camera
The SH3 Series high-speed camera from SinceVision is designed for scientific research and industrial applications. The SH3 Series uses a 20-layer printed circuit board stacking design to help with...
SinceVision
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High-Throughput Screening Cytometer
Sartorius’ iQue® 5 High-Throughput Screening Cytometer has up to 27 channels and flexible workflows in 96- and 384-well formats. The cytometer supports continuous runtimes of up to 24 h,...
Sartorius AG
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sCMOS Camera
The Aries 6504 scientific CMOS (sCMOS) camera from TUCSEN features a 2048 × 2048 array of 6.5-μm back-illuminated pixels with a peak quantum efficiency of 95%, speeds of up to 300 fps, and...
Tucsen Photonics Co. Ltd.
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Perovskite Crystals
AY Sensors’ 25 × 25 mm² larger-format perovskite single crystals are used for direct x-ray detection and imaging applications. The crystals are available as grown, polished, and...
AY Sensors Inc.
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Femtosecond Laser
Osprey from Coherent Corp. is a femtosecond laser for applications in optogenetics, microsurgery, and medical device manufacturing. Osprey has pulse energies of up to 5 µJ and sub-350 fs pulse...
Coherent Corp.
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Latest News
Hybrid Microscopy Technique Follows Influenza’s ‘Trojan Horse’
Dec 31, 2025
IR Spectroscopy Could Diagnose Lung Cancer with Blood Sample
Dec 30, 2025
Optogenetics Helps Clarify Link Between Brain Plasticity and Huntington’s Disease
Dec 24, 2025
Octopus-Inspired Micro-LEDs Designed for Cancer Therapy
Dec 18, 2025
Brain Imaging Tool Bypasses the Bottlenecks Faced by Fluorescent Probes
Dec 17, 2025
Philips to Acquire Intravascular Imaging Specialist SpectraWAVE
Dec 17, 2025
Imagine Optics Acquires Karthala Systems, Expanding Bioimaging Capabilities
Dec 16, 2025
Integrated Source-Sensor Produces and Detects FS UV-C Pulses
Dec 16, 2025
Implant Device Communicates With Brain Through Light
Dec 12, 2025
Self-Trapped Light Enables Autonomous Computing in Soft Material
Dec 2, 2025
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