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Quantum Dots Move Beyond Fluorescence Imaging

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The unique properties of quantum dots allow them to be optimized for voltage sensing and for light-controlled electrical activation of cells.

Dr. Elena Molokanova, Joseph A. Bartel, Dr. Weiwen Zhao, Dr. Imad Naasani, Dr. Michael J. Ignatius,
Dr. Joseph A. Treadway, Dr. Alex Savtchenko, Invitrogen Corp.

Quantum dots are transforming life sciences imaging because of their extraordinary photostability, brightness, broad excitation, narrow emission, long fluorescence lifetimes and multiplexing capability. The nanometer-scale inorganic crystals contain a few hundred to a few thousand atoms of a semiconductor material, and their behavior is governed by the laws of quantum physics. Quantum dots are not quite a molecule, although they have discrete electronic energy levels, and they are not a bulk semiconductor, either, although they demonstrate spin-orbit coupling and have large dielectric...Read full article

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    Published: June 2008
    Glossary
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
    quantum dots
    A quantum dot is a nanoscale semiconductor structure, typically composed of materials like cadmium selenide or indium arsenide, that exhibits unique quantum mechanical properties. These properties arise from the confinement of electrons within the dot, leading to discrete energy levels, or "quantization" of energy, similar to the behavior of individual atoms or molecules. Quantum dots have a size on the order of a few nanometers and can emit or absorb photons (light) with precise wavelengths,...
    Basic ScienceBiophotonicsCoatingsCommunicationsFeaturesfluorescencelife sciences imagingquantum dotsSensors & Detectors

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