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Photoacoustic Technique Captures Real-Time Anomalies in Microvasculature

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DOUGLAS FARMER, SENIOR EDITOR
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LONDON, Oct. 16, 2024 — By using a laser to generate ultrasound waves that reveal structural changes, photoacoustic tomography (PAT) has shown its value in identifying disease conditions in the microvasculature, the tiny vessels that extend from major veins and arteries. To this point, however, the process has been too slow to capture this information in real time, limiting its value in clinical settings. That is now changing, thanks to a device developed at University College London (UCL) that doctors could potentially hold right in their hands. Traditionally, PAT scans have required a patient to remain...Read full article

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    Published: October 2024
    Glossary
    photoacoustic
    Photoacoustic refers to the generation of acoustic (sound) waves following the absorption of light (usually laser pulses) by a material. This phenomenon occurs when light energy is absorbed by a material, leading to localized heating and subsequent thermal expansion, which generates pressure waves (sound waves) that can be detected using ultrasonic sensors. The photoacoustic effect is utilized in various scientific and medical applications, including: Photoacoustic imaging (PAI): A...
    optical parametric oscillator
    A laser-pumped crystal with nonlinear optical properties inside of an optical resonator in which the output generates coherent light whose output can be tuned continuously over a variety of infrared and visible wavelengths. The OPO generates a short wavelength component called the signal and a longer wavelength component called the idler. Conservation of energy dictates that the sum of the photon energy of the signal and that of the idler equals the original pump photon energy.
    optical fiber
    Optical fiber is a thin, flexible, transparent strand or filament made of glass or plastic used for transmitting light signals over long distances with minimal loss of signal quality. It serves as a medium for conveying information in the form of light pulses, typically in the realm of telecommunications, networking, and data transmission. The core of an optical fiber is the central region through which light travels. It is surrounded by a cladding layer that has a lower refractive index than...
    Research & TechnologyphotoacousticImagingPhotoacoustic tomographyultrasoundmicrovasculaturecirculatoryoptical parametric oscillatorLasersoptical fiberdiagnosticsblood vesselsNature Biomedical EngineeringUniversity College LondonEurope

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