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Intravascular Near-Infrared Spectroscopy Predicts Heart Attacks

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Identifying lipid deposits that put patients at higher risk of major adverse cardiovascular events enables early clinical treatment of coronary disease.

NICHOLAS C. GIGLIO, SAMANTHA FARROW, KAVYA SREERAM, AND STEPHANIE GRAINGER, INFRAREDX, A NIPRO COMPANY

Lipoproteins carry cholesterol through the closed-looped vascular hematological highway of the human body. This cholesterol can embed itself into the artery walls at varying rates, depending on a multitude of factors, such as anatomical influences or genetic predispositions. Cholesterol vascular wall infiltration triggers the body’s immune response to multiply collagen and muscle cells in these specific regions of vascular tissue, forming a fibrous cap over the lipid deposit (Figure 1). A progression of optical technologies has been put to work to capture these deposits — most...Read full article

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    Published: May 2023
    FeaturesNIR spectroscopycoronary arterieslipoproteinscholesterolInfraredxlipid core plaque burdenmajor adverse cardiovascular eventsOCTintravascular ultrasoundChemometricsPROSPECT IIPROSPECT ABSORBPACMAN-AMIYELLOW3

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