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Frequency Division Multiplexed Fluorescence Confocal Microscopy

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Dr. Stuart Yin, Pennsylvania State University

High-speed, multichannel fluorescence confocal imaging can be achieved by encoding the spatial location information into the frequency domain. Fluorescence confocal microscopy is an important tool for studying live biological cells, and it can reject out-of-focus fluorescence so that an image with a high signal-to-noise ratio can be obtained over the scattering biomedical media. To understand cellular systems, it is necessary to observe fast biological processes — such as cardiac myocyte contraction — in real time. Multichannel methods can increase imaging speed; however,...Read full article

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    Published: December 2006
    BiophotonicsCommunicationsFeaturesMicroscopySensors & Detectors

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