Light-Activated Gene Expression Could Uncover Cancer Therapies
KYOTO, Japan, July 25, 2017 — In a novel approach to light-inducible gene regulation, researchers began by modifying the surface of nanorods to make them more efficient in transporting cancer-killing genes to cells. The gold nanorods, which produce heat when exposed to a NIR laser, were coated with two conventional lipids, oleate and dioleoyl-3-trimethylammonium-propane (DOTAP). The lipids enhanced the nanorods’ ability to interact with and penetrate cells efficiently, while maintaining low