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Correction Systems for Deep Imaging Drive More Precise Views
Multiphoton microscopy is widely regarded as the primary technique for deep imaging in live tissue. However, image brightness and resolution are typically poorer at deep sites because of increased optical spherical aberration compared to superficial locations. This makes it difficult to study fine structures, such as dendritic spines in deep brain regions. Microscope objectives equipped with adjustable correction collars can compensate for spherical aberration and improve resolution
BioPhotonics, May/Jun 2019
Medical Lasers Find Their Niche
Because lasers can offer less-invasive procedures for both diagnosis and treatment, their role in the medical field is on the rise. Lasers can be modulated in wavelength, power, density, and energy, and they have a wide range of applications in...
BioPhotonics, May/Jun 2019
LASER World of PHOTONICS 2019: An Innovation Playground
With a first-rate portfolio, LASER World of PHOTONICS (Laser Munich) is a one-stop shop for research and technology, industry, and academia — showcasing numerous photonics components, systems, and applications. The biennial conference and...
BioPhotonics, May/Jun 2019
Computational Imaging Builds Better Pictures
A picture may be worth more than a thousand words after passing through mathematical algorithms and modern computer hardware. Such a process, known as computational imaging, can speed up data acquisition significantly, thereby allowing the use of...
BioPhotonics, May/Jun 2019
IR Light Illuminates Biotech Manufacturing
Medicine and biotech industries make and utilize high volumes of custom pieces, including prosthetics, implants, personalized medicine, and large-scale medical devices. Getting these products to market faster and more efficiently can save millions...
BioPhotonics, April 2019
Ultrashort-Pulse Lasers: Emerging Tools for Biomedical Discovery
From nonsurgical vision correction to multiphoton imaging to neuronal optogenetics, ultrashort-pulse lasers — also informally known as ultrafast lasers — have become essential tools in biomedical discovery. VEGFR3-positive (red)...
BioPhotonics, April 2019
Upconversion Materials Empower Thermal Bioimaging
Bioimaging is a fundamental technique for research in the life sciences, and it is used routinely in the medical industry. The procedure itself encompasses many different methods, such as electron microscopy, x-ray tomography, and magnetic resonance...
BioPhotonics, April 2019
Photobiomodulation Tools Highlight Research Needs
More than 50 years ago, when lasers were a new phenomenon, a Hungarian researcher applied a low-powered ruby laser to mice and noticed it stimulated hair growth and wound healing. To date, over 500 clinical trials and 4000 laboratory studies have...
BioPhotonics, April 2019
Prism Award Winners Take Center Stage
Amid the bustle of Photonics West, some of the industry’s top innovators gathered on Feb. 6 to honor the best products and advancements at the “Oscars of the photonics industry” — the Prism Awards for Photonics Innovation....
Photonics Spectra, March 2019
ASLMS 2019 Promotes Medical Excellence
Lasers, laser systems, and related applications will take the spotlight March 27-31 at the Colorado Convention Center in Denver during the conference of the American Society for Laser Medicine and Surgery (ASLMS). Focuses include nursing, patient...
BioPhotonics, Feb/Mar 2019
AO-OCT Comes into Focus
Adaptive optics (AO) technology is often used to correct for wavefront distortions imparted when light travels through complex optical systems, enhancing image resolution and facilitating diffraction-limited optics. It has played a particularly...
BioPhotonics, Feb/Mar 2019
Dual Imaging Method Holds Promise as a Tool for Cancer Diagnostics
Since Bell Labs first described the photoacoustic effect — the conversion of light to sound — in the late 1800s1, researchers have explored the principle for medical imaging purposes2,3. Over the past decade, advancements in lasers,...
BioPhotonics, Feb/Mar 2019
The Growing Role of Lasers in Treatments for Better Blood Flow
For some cardiovascular patients, laser-based procedures have become the best, and perhaps only, option to relieve pain and restore function associated with many diseases of the heart, arteries, and veins. New wavelengths, more rugged setups,...
BioPhotonics, Feb/Mar 2019
Member Exclusive
Novel Multiphoton Imaging Techniques Reveal Brain’s Secrets
Nearly two decades ago, Winfried Denk and Karel Svoboda argued in the journal Neuron that “multiphoton imaging is more than a gimmick”1. At the time, confocal microscopy — combined with advancements in fluorescent reporter systems...
BioPhotonics, Feb/Mar 2019
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Research, Innovation Lead SPIE BiOS 2019
SPIE’s BiOS conference and exhibition is renowned worldwide as one of the most important events in the biophotonics industry. It brings together researchers, professors, students, companies, and other industry experts for a weekend of...
BioPhotonics, January 2019
PDT, Customized Protocols Team Up for Enhanced Clinical Translation
Photodynamic therapy is a powerful technique in the local, selective treatment of cancer and infectious diseases, but customized optical device protocols must be added to the mix for major clinical translation. Photodynamic therapy (PDT) is a robust...
BioPhotonics, January 2019
Advancements in Raman Spectroscopy Find Real-World Uses in the Life Sciences
Since its development in the mid-1920s, Raman spectroscopy has been used to study various low-frequency vibrational modes in molecular systems. In contrast to its counterpart — Fourier transform infrared spectroscopy (FTIR), which probes...
BioPhotonics, January 2019
Molecular Imaging Emerges as a Cancer Surgery Tool
Molecular imaging has become an invaluable tool in cancer treatment. Single-photon emission computed tomography (SPECT) and positron emission tomography (PET) are entering routine clinical use for preoperative imaging. These techniques visualize...
BioPhotonics, January 2019
Prism Award Finalists Vie for 2019 Honors
The Prism Awards for Photonics Innovation bring anticipation and excitement each year to the Photonics West exhibition in San Francisco. Renowned as the “Oscars of the photonics industry,” the Prism Awards shine a spotlight on some of...
BioPhotonics, January 2019
Member Exclusive
Wearable Sensors Challenge Traditional Medical Technology
From Apple to Fitbit to Garmin to Google, in the U.S. alone, dozens of companies are producing wearable sensors that record our movements as well as basic health information. Many of these devices rely on optical telemetry to read information about...
Photonics Spectra, August 2019
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ASCB|EMBO Highlights Cell Biology Innovation
What do phase transitions in neurological disease, superresolution imaging of living mammalian cells, and stem cells in bone marrow have in common? All of these topics (and more) will be addressed at the 2018 ASCB|EMBO Annual Meeting and Conference...
BioPhotonics, Nov/Dec 2018
FTIR Spectroscopy: A Comprehensive Biological Investigator
Almost every molecule in the universe interacts with IR radiation, which excites vibrations in the molecule, rendering Fourier transform IR (FTIR) spectroscopy a universal method to investigate biological systems. In contrast to many popular...
BioPhotonics, Nov/Dec 2018
Quantitative Phase Imaging Advances Disease Detection
Following unprecedented success in controlling malaria worldwide, progress is now slowing. In fact, a 2017 report by the World Health Organization (WHO)1 clearly indicates that the world is no longer on track to reach the critical milestones for...
BioPhotonics, Nov/Dec 2018
Optimizing Probe Positioning for Life Science Research
Photonics technologies enable life scientists to probe samples in the increasingly sophisticated study of processes ranging from neuron signaling to heart muscle contraction, as well as cells and cellular development. As research continues at...
BioPhotonics, Nov/Dec 2018
Hand-Held AO Ophthalmoscopy Enables Cellular-Level Imaging
Advancements in adaptive optics (AO) are bringing researchers deeper into the human retina than ever before. Enabling the visualization of the living retina with cellular resolution, AO scanning laser ophthalmoscopy (AOSLO) has advanced the...
BioPhotonics, Nov/Dec 2018
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