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FEATURES
Plasmonic Tip Detects Viruses’ Raman Signal
Scientists and health experts searching for a tool that will help in the diagnosis of COVID-19 today as well as prepare for the pandemics of tomorrow may soon find a solution in a suite of techniques based on the Raman effect. Raman spectroscopy relies on the optical read-out of rich and molecule-specific, fingerprint-like spectra of molecular vibrations. This technology can be applied to chemical identification and sensing. And now coherence-enhanced and plasmonic tip-enhanced Raman...
BioPhotonics, Sep/Oct 2021
Camera Optimization Helps to Clarify In Vivo Diagnosis and Plan Treatment
Pre-clinical in vivo studies are essential to our understanding of human disease, as well as to the development and administration of new treatments and therapeutic agents. Noninvasive, pre- clinical, in vivo imaging techniques allow for long-term...
BioPhotonics, Sep/Oct 2021
NIR Fluorescence Captures Clear Images of Cancerous Tumors During Surgery
Despite discoveries made in cancer research in recent years, few new techniques have significantly changed the course of the disease, which is responsible for more than 25,000 deaths in the U.S. every day. Surgery is usually the most effective...
BioPhotonics, Sep/Oct 2021
OCT Presents Multidimensional Imaging for Diagnosis and Detection
Optical coherence tomography (OCT) is a noninvasive imaging technique that is used to deliver high-resolution images in two or three dimensions. It relies on the wave-like properties of light to produce a low- coherence interference spectrum. In...
BioPhotonics, Jul/Aug 2021
Smart Probe Captures Biomarker Sequence
A smart probe is a hairpin oligonucleotide, essentially a string of nucleic acids, that is labeled with a fluorophore on one end and tethered with successive guanosine residues on the other end. Extrinsic dye labels with suitable absorption are...
BioPhotonics, May/Jun 2021
Plasmonics and Microfluidics Speed Detection of Lyme Disease
When a person develops Lyme disease from a tick bite, identifying the tiny culprit can be challenging. The insect itself is difficult to see in the grass or forested area it comes from before burrowing into the person’s skin. The symptoms of...
BioPhotonics, May/Jun 2021
Liquid Crystal Sensors Provide Rapid COVID-19 Diagnosis
The global outbreak of COVID-19 has prompted scientists worldwide to focus their research on the virus over the last year, particularly those who work with optical and sensing technologies. Some have concentrated on understanding fundamental aspects...
BioPhotonics, Jul/Aug 2021
Charge Clusters in a Monomeric Protein Alter Optical Absorption
Electronic absorption of proteins that lack cofactors, prosthetic groups, or noncoded amino acids as part of their structure has traditionally been thought to originate from protein backbone (peptide bond) and aromatic chromophores in the side...
BioPhotonics, Jul/Aug 2021
Quantum Cascade Lasers Boost Life Science Research
Over 20 years have passed since the first quantum cascade laser (QCL) sources were commercialized. QCLs that operate at room temperature using thermoelectric cooling are now ubiquitous. These lasers ushered in a new era of infrared spectroscopy. In...
BioPhotonics, Jul/Aug 2021
ASLMS 2021 Examines Laser-Based Treatments, Diagnosis in Online Setting
Following the cancellation of last year’s event, this year’s conference of the American Society for Laser Medicine and Surgery (ASLMS) will rebound with a virtual presentation of the latest in laser-based science and research. Registration is open...
BioPhotonics, Mar/Apr 2021
Microscopy Technique Enhances 3D Imaging Capability
Optical microscopes use light to visualize detailed structures of small samples. The most popular microscopy technique for biological or biomedical studies by far is wide-field microscopy, in which a sample, such as tissue, is imaged through a...
BioPhotonics, Mar/Apr 2021
Diode Array Spectrometers Augment Fluorescence-Based Research
Fluorescence spectroscopy is an established method for detecting concentrations of biological material in medicine or in environmental analysis. The key benefit of using fluorescence over other techniques of spectral analysis such as UV absorbance...
BioPhotonics, Mar/Apr 2021
Eye Care, Laser Technology, and Imaging Modules Among 2021 Prism Award Finalists
Six biophotonics technologies that enhance retinal imaging, disease diagnosis, and surgical precision are among the 30 finalists SPIE has selected for this year’s Prism Awards. Winners in 10 categories will be announced as part of the SPIE...
BioPhotonics, Jan/Feb 2021
Multiplex Imaging Captures Cellular Processes
Ongoing innovations in optical microscopy have fueled life science research, allowing scientists to visualize how complex biological systems work and break down. These developments have required specifications beyond the need for high-resolution...
BioPhotonics, May/Jun 2021
Light Sheet Microscopy Enables 3D Pathology
Pathology for cancer diagnosis today relies on manual processing and an individual’s assessment of 2D samples. While this method has been established for over a century, the process has limitations. It can introduce inter-observer variability, and...
BioPhotonics, May/Jun 2021
Spectroscopy Takes Root in Agricultural Analysis
Technical advancements have dramatically changed the processes that people use when farming. For example, to ensure optimal crop placement and fertilization, optical sensing techniques provide finely detailed analysis of local soil characteristics...
BioPhotonics, Mar/Apr 2021
Pulsed Lasers Pierce the Diffraction Limit in Medicine
Optical imaging of tissues in diagnostics is a burgeoning field of research, and related technology has shown the ability to provide rapid, sensitive, and specific data that discriminates disease-related characteristics. However, the depth at which...
BioPhotonics, Jan/Feb 2021
Chip-on-Tip Technology Expands Endoscopy’s Use in Localized Procedures
Many patients would prefer to undergo surgery in which tools enter their bodies through a natural opening or small incision, over an operation involving the opening of their chests or abdominal cavities. Improvements in medical imaging over the past...
BioPhotonics, Jan/Feb 2021
Photoacoustic Imaging Identifies Transplantable Kidneys
Chronic kidney disease is a condition that causes the gradual loss of kidney function over a period of months to years. The prevalence of the disease is worsened by the alarming rise of diabetes and hypertension, two of the most common causes of...
BioPhotonics, Jan/Feb 2021
Mobile Spectroscopy Enables Noninvasive Blood Hemoglobin Assessments
As one of the most routinely performed laboratory tests, a blood hemoglobin test is used to measure levels of the oxygen-carrying protein in the blood. Potentially reduced levels are commonly associated with certain conditions. Clinics order the...
BioPhotonics, Jan/Feb 2021
Spectroscopy Guides Precision Medicine
Raman spectroscopy captures the effect when light partially scatters inelastically as it interacts with matter. The amounts of energy transferred between photons and molecules during this process correspond to specific molecular vibrations....
BioPhotonics, Nov/Dec 2020
Veterinarians Use OCT to Evaluate Eye Health, Cancer Margins, and Joint Strength
Medical doctors have long understood the value of optical coherence tomography (OCT) for monitoring human health. Veterinarians are learning that the technology can be just as vital in evaluating the well-being of patients in the animal kingdom....
BioPhotonics, Nov/Dec 2020
Inaugural
Photonics Spectra
Conference to Highlight Innovations in Lasers, Optics, More
The first Photonics Spectra Conference is set for Jan. 19-22, featuring presentations in four tracks: lasers, optics, biomedical imaging, and spectroscopy. Each day-long program will feature a keynote address and sessions that highlight the latest...
Photonics Spectra, December 2020
Angiographic OCT Images Forewarn of Disorders Caused by Maternal Drug Use
No amount of alcohol is considered safe during pregnancy, according to published research1. Despite this message being the subject of constant public service warnings, in a recent study, 20% to 30% of women in the U.S. reported drinking during...
BioPhotonics, Nov/Dec 2020
OCT Informs Real-Time Cancer Diagnosis
The origins of optical coherence tomography (OCT), a subsurface imaging technology based on low- coherence interferometry, can be traced to the first decade of the 1800s, when Thomas Young’s double-slit interference experiment showed that light...
BioPhotonics, Nov/Dec 2020
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