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BioPhotonics - May/Jun 2022
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Issue Library
Digital Edition
Features
Fluorescence Imaging Deepens the View: From Single Cells to the Subcellular
The human body is made up of trillions of cells, and each one is as unique as the person it is part of. Each individual cell is arranged alongside its neighbors in a specific pattern that is...
Hyperspectral Imaging Characterizes Healthy and Diseased Tissues During Surgery
Upgrades in medical imaging technology have made possible the accurate diagnosis and successful treatment of ailments ranging from broken bones to cancer. Techniques such as endoscopy keep evolving...
QCL-IR Microscopy: Delivering Molecular Information at Unprecedented Speed
As microspectroscopic imaging applications have expanded, analytical scientists have demanded advancements from existing imaging technology. Such advancements are particularly critical for biomedical...
AI Bridges the Gap Between Medical Imaging and Analysis
Improvements in the automation of functional mechanical, electrical, and optical components — along with increasing computing power for image analysis — have enabled the development of...
Editorial
AI brings swift diagnosis
Medical imaging modalities are now faster and more powerful than ever before, capturing thousands of images of diseased and healthy tissue. These images represent a vast resource for researchers and clinicians who track the progression of viruses or other illnesses under a microscope. The images reveal cellular dynamics that have developed within the patient, as well as similar changes in samples...
BioScan
Laser Speckle Method Captures Blood Flow in Microvasculature
Researchers at the National University of Singapore developed a confocal laser speckle autocorrelation method to image dynamic flow in microvasculature. The technique is label-free and enables real-time and quantitative imaging of blood flow on the microscopic level. The system shares many characteristics of a confocal fluorescence microscope; like the confocal fluorescence microscope, it is able...
Fluorescent Dye-Based Device Could Help Prevent Tooth Decay
An optical device in development at the University of Washington (UW) could help prevent tooth decay by identifying at-risk teeth before cavities have had a chance to start to develop. The prototype,...
Committee Releases Draft of OCT Guidelines, Standards
Representatives from the business and research sectors have developed a first draft of guidelines with standardized process descriptions for optical coherence tomography (OCT). The VDI/VDE Society...
Lensless Camera Captures Cellular-Level Details in 3D
Rice University researchers have tested a tiny lensless microscope called Bio-FlatScope, capable of producing high levels of detail in living samples. The team imaged plants, hydra, and, to a limited...
Transparent Chip Provides View to Multimodal Imaging
A transparent, biocompatible ultrasound transducer chip developed by researchers from Penn State is opening opportunities in cell and tissue stimulation and multimodal imaging. The chip, called a...
Method Keeps Liquid Marbles Functional for Microfluidic Systems
A research team from Griffith University developed a technique that uses condensation to noninvasively refill liquid marbles with water. The method could improve the viability of applications such as...
Optica Names 2022 Award Winners for Service in Photonics
Optica has announced 20 recipients of its 2022 awards and medals. The awards celebrate individuals who have achieved significant technical, research, education, business, leadership, and service...
Rescue Act Funds AIM Photonics' Production of Lab-on-Chip Tests
The U.S. Department of Commerce’s National Institute of Standards and Technology (NIST) has earmarked more than $10 million for photonic technologies addressing the ongoing pandemic. More than...
Ocean Insight Acquires ILT, Adds Light Measurement Capabilities
Ocean Insight has acquired International Light Technologies (ILT), a producer of light measurement and detection systems and customized light source solutions. ILT’s offerings are used in...
Thin Film Allows Metasurface Lens to Change Focus
A research team headed by Christopher Dirdal from SINTEF Smart Sensors and Microsystems in Norway has created a metasurface lens that uses a piezoelectric thin film to change focal length when a...
TRUMPF Acquires Majority Stake in Active Fiber Systems
TRUMPF has acquired an 80% stake in Active Fiber Systems GmbH (AFS), a company based in Jena, Germany. AFS develops and manufactures ultrashort-pulse laser systems and fiber laser systems used...
Kinetic River Advances Compensation-Free Flow Cytometry
Kinetic River Corp. reported that it has advanced its Arno technology for time-resolved cell analysis, developing technology that enables compensation-free, 12-marker flow cytometry assays with just...
Three-Photon Microscopy Reveals Immune Cell Behavior in Real Time
A research group from Cornell University has used three-photon microscopy to image the full depth of the popliteal lymph node in a living mouse — reportedly for the first time. The researchers...
3 Questions
3 Questions with Keith Paulsen
BioPhotonics spoke with Keith Paulsen, the Robert A. Pritzker Professor of Biomedical Engineering at Dartmouth College’s Thayer School of Engineering. Paulsen and his colleagues recently published a paper about the use of a deep learning algorithm to accelerate the reconstruction of tissue images by combining scans from MRI together with diffused optical signals from near-infrared spectral...
BioOpinion
The lack of standard metrology tools impedes the pace of microfluidics development
Medical imaging modalities are now faster and more powerful than ever before, capturing thousands of images of diseased and healthy tissue. These images represent a vast resource for researchers and clinicians who track the progression of viruses or other illnesses under a microscope. The images reveal cellular dynamics that have developed within the patient, as well as similar changes in samples...
Postscripts
The butterfly effect
Tiny changes can make a large difference in the way the world develops. This is known in chaos theory as the “butterfly effect,” a concept that may be easy to understand when it comes to how human behaviors — whether a gesture, a decision, or a habit — can affect other people. But it’s more difficult to grasp on the deeper biological level of cells, proteins, and...
Products
IR Platform for Testing Liquid Foods
The LQA300™ FT-IR liquid food testing platform from PerkinElmer Inc. includes cloud based-software and streamlined workflows to deliver results in <45 s. Using Fourier transform IR technology, the platform tests the quality and safety of liquid foods such as wine, dairy, and others, identifying key quality markers including alcohol, sugar, acidity, pH, and density levels during...
PerkinElmer (See Revvity)
OEM Spectrometer
The Cobra OEM spectrometer from Wasatch Photonics is designed specifically for ease of integration by OEMs into optical coherence tomography (OCT) imaging systems. Optimized for 800-nm spectral...
Wasatch Photonics Inc.
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Imaging Platform
The Mica Microhub from Leica Microsystems GmbH is an imaging platform that uses machine learning software, automation tools, and fluorescence unmixing techniques to automate imaging workflows for...
Leica Microsystems GmbH
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Thermal Sensor
The Ophir F150(200)A-CM-16 thermal sensor from MKS Instruments Inc. measures high repetition rate lasers with short pulses in the nanosecond, picosecond, and femtosecond ranges. The compact,...
MKS Instruments Inc.
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Green and Yellow Laser Modules
The GLM series of green and yellow laser modules from Frankfurt Laser Co. now feature 520-, 555-, and 577-nm wavelengths. The devices are offered with up to 1-W output power, fast rise time,...
Frankfurt Laser Company
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Mass Photometer
The Two Auto photometer from Refeyn Ltd. provides automated protein characterization at the single-molecule level in solution. The instrument provides researchers with automated, direct mass...
Refeyn Ltd.
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Femtosecond Laser Sources
The CRONUS-2P and CRONUS-3P microscopy-dedicated femtosecond laser sources from Light Conversion covers applications in functional neuroimaging, optogenetics, and deep imaging. CRONUS-3P...
Light Conversion
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UV Laser Modules
The 375-nm UV Photon laser modules from ProPhotonix Ltd. are available in power levels up to 70 mW and well-suited to UV curing applications that require fast curing from a very focused UV light. ...
ProPhotonix Ltd.
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Thermal Science Cameras
The X858x and X698x X-Series science cameras from Teledyne FLIR provide high-speed and high-resolution thermal imaging for scientific research and engineering applications within the MWIR and LWIR...
Teledyne FLIR Systems Inc.
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