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BioPhotonics - Jul/Aug 2023


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Features
Fluorescence Polarization Approach Allows Quantitative Cancer Diagnosis Fluorescence polarization (Fpol) is an optical phenomenon that characterizes the polarization of fluorescence emissions relative to the polarization state of the excitation light. It is sensitive to...
Precision Positioning Aids Microscopes with Tracking Viral Progression The rapid spread of COVID-19 and other diseases has shown that understanding viral infection is critical to the health of people around the world. In particular, understanding the dynamics of the...
Quantitative Phase Imaging Advances Regenerative Medicine Regenerative medicine is defined as the process of replacing, engineering, or regenerating human or animal cells, tissues, or organs to restore or establish their normal function. Researchers have...
Hyperspectral Imaging Allows the Simultaneous Measurement of Fluorophores Hyperspectral imagers provide an image that produces a detailed spectrum for every pixel, capturing very minute details in a sample. Typically, this technology has been used to measure the spectral...
Editorial
Gaining an edge in cancer diagnostics Fluorescence polarization imaging, which measures the polarization of specific fluorophores relative to excitation light, has recently become a tool with which clinicians have sought to clearly delineate the boundaries of various types of cancers in the body. The fluorescence from agents such as methylene blue have traditionally been used to indicate the existence of cancerous cells in biopsy...
BioScan
LEADOPTIK Raises $5M in Seed Funding to Commercialize Imaging System Medical imaging company LEADOPTIK has raised $5 million in an oversubscribed seed funding round. The funding will allow LEADOPTIK to move to the next stage of product development on the path to commercialization. The company is developing a miniaturized imaging system to image deep within human lungs to allow for early diagnosis of cancer. Combining novel nanofabrication and innovative optical...
Wearable Brain-Imaging Offers Alternative to 'Gold Standard' Method Researchers at Washington University in St. Louis are developing an alternative to the current gold standard of brain imaging, functional magnetic resonance imaging (fMRI). The researchers’...
Spatial Light Modulation Gauges How Lenses Slow Progress of Myopia Myopia, or nearsightedness, is one of the most common ocular disorders worldwide and a leading cause of visual impairment in children. Although specialized eyeglass lenses have been clinically tested...
Cell Manipulation Technique Enters into Commercial Market In cell biology and medical imaging, the targeted manipulation of cells under controlled conditions is a major challenge in understanding processes and causal relationships. Researchers are dependent...
FPGA-Based Data Compression Drives Brain Imaging Performance Gains To help broaden the use of single-photon avalanche diode (SPAD) cameras for multispeckle diffuse correlation spectroscopy (DCS), researchers at the University of Edinburgh developed a data...
Lumibird to Acquire Convergent Photonics from Prima Industrie Laser developer Lumibird has signed an agreement to acquire Convergent Photonics, a subsidiary of Italian company Prima Industrie, as well as the Convergent assets of Prima Industrie North America....
Paper-Based Test Scans for Multiple Biomarkers in Human Serum Researchers led by UCLA professor Aydogan Ozcan developed a deep learning-enabled biosensor for multiplexed, point-of-care (POC) testing of disease biomarkers. POC biosensors provide remote and...
Danish Government Blocks Sale of NKT Photonics to Hamamatsu The sale of NKT Photonics to Hamamatsu Photonics subsidiary Photonics Management Europe srl has been denied under the Danish Investment Screening Act. Required regulatory approvals for the agreement...
Meadowlark Optics Acquires Boulder Nonlinear Systems Meadowlark Optics has announced its acquisition of Boulder Nonlinear Systems (BNS). Both companies are based in Colorado and produce optical components used in numerous scientific research fields and...
IDEX Corp. Acquires Iridian Spectral Technologies Illinois-based IDEX Corp. has agreed to acquire Iridian Spectral Technologies, an Ottawa, Ontario-based developer and manufacturer of optical filters for applications spanning remote sensing, medical...
Coated Guidewire Boosts Intravascular Assessment Accuracy Cardiologists use intravascular near-infrared fluorescence (NIRF) imaging with intravascular ultrasound (IVUS) and other imaging modalities to examine blood vessels and assess cardiovascular health....
Remote Sensing Aids Photoacoustic Microscopy in Tissue Mapping Researchers at the University of Hong Kong showed that biological tissue can be imaged with greater sensitivity through remote sensing of photoacoustic signals than through conventional photoacoustic...
Century-Old Effect Applied for Study of Embryonic Development Researchers have applied line-scanning Brillouin microscopy (LSBM), a microscopy technique based on Brillouin scattering, to visualize the mechanical properties of living cells over space and time,...
BioOpinion
Equitable and fair AI for health care requires a team effort The potential for bias and unfairness in the integration of AI in health care-centered research and diagnostics, particularly in medical image analysis, must be addressed to ensure equitable and effective outcomes for all patients. Biases can occur during the implementation of any of the five steps of the imaging AI model development pipeline, as our Medical Imaging and Data Resource Center...
Postscripts
UV signals from orchids entice bees to visit In the animal kingdom, certain species are adept at camouflaging themselves to blend in with their surroundings to avoid the attention of predators. But in the plant kingdom, certain species of flowers blend in with their surroundings to increase the attraction of pollinators. Such is the case with Diuris brumalis, otherwise known as the donkey orchid, which grows in western Australia. Those who...
Education Special Section
Malley Richardson Awarded 2023 Teddi C. Laurin Scholarship for Research in Optofluidics Malley Richardson, a mechanical engineering student at the University of British Columbia (UBC), has been awarded the 2023 Teddi C. Laurin Scholarship for her contributions to the field of optics and photonics. Richardson is actively engaged in optofluidics R&D and is working to develop optofluidic sensors for the health sector. Her areas of interest include the development of lab-on-a-chip...
Products
CW Diode-Pumped Laser HÜBNER Photonics has released a higher power model of the Cobolt Jive™ 561-nm laser on the 05-01 series platform. With up to 1000-mW continuous wave output power, the laser can be used for demanding applications in fluorescence microscopy and super-resolution microscopy. The laser offers a continuous-wave, single-frequency, diode-pumped design with power stability and ultralow...
HUBNER Photonics GmbH
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VCSEL Laser Diode The single-mode 850-nm vertical-cavity surface-emitting laser (VCSEL) diode from IMM Photonics GmbH is contained in a compact TO46 housing. The device can be used as a laser light source for...
IMM Photonics GmbH
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Raman Spectrometers The RASP1 and RASP2 Portable Coded-Aperture Raman Spectrometers from Thorlabs Inc. are designed for detecting low-intensity Raman signals and can analyze the chemical composition of solid and liquid...
Thorlabs Inc.
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Upright Microscope The ECLIPSE Ni-L upright microscope from Nikon Corp. features LED illumination that closely resembles natural light. The device enables accurate display of specimen colors, making it effective...
Nikon Instruments Inc.
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Spectrometers The Ocean SR series of spectrometers from Ocean Optics offers rapid spectral acquisition speed and high signal-to-noise ratio performance. The devices include different models with varying...
Ocean Optics
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Cooled sCMOS Cameras Ximea’s MJ042MR-GP-P11-BSI-UV model was added to its portfolio of scientific cameras. It’s equipped with a Gpixel PulSar sCMOS sensor that is combined with Peltier cooling and USB3...
XIMEA GmbH
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Camera Block The FCB-EV9520L camera block from Sony Image Sensing Solutions is based on the 2-MP Starvis™ two-color image sensor. The 1/2.8-in. unit supports full HD resolution with a wide dynamic...
Sony Europe Ltd., Image Sensing Solutions
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Microscopy Software Version 4.1 of the SLIDEVIEW™ VS200 microscopy software from Olympus Corp. and Evident Scientific adds an optical sectioning device for high-contrast, blur-free imaging. The SILA optical...
Evident
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Confocal Microscope System The CICERO system from CrestOptics is an all-in-one solution for widefield and confocal imaging, offering integration into existing workflows with configuration flexibility enabling a broad range of...
CrestOptics SpA
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UV-VIS System The Agilent Cary 3500 flexible UV-Vis system from Agilent Technologies is a double-beam spectrophotometer equipped for diverse sample-type measurements with minimal sample preparation, well-suited...
Agilent Technologies Inc., Chemical Analysis
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CMOS Camera The Atlas10 camera from LUCID Vision Labs Inc. features the 65-MP Gpixel GMAX3265 image sensor. The high-performance camera delivers image quality and speed for applications that require high...
LUCID Vision Labs Inc.
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In Vitro Diagnostic Software The MALDI Biotyper® In Vitro Diagnostic Software from Bruker Corp. provides fast microbial identification. The software provides a high sample throughput for microbial identification with...
Bruker Optics Inc.
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Linear Actuator The LSA14 from Nanotec is a linear actuator with 14-mm flange (NEMA 6), as well as a stepper motor. Its small size is suited for applications with space restrictions, such as medical or analytical...
Nanotec Electronic GmbH & Co. KG
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Vital Sign Measurement Photodiode The TOPLED® D5140, SFH 2202 photodiode from ams OSRAM provides high sensitivity for wearable devices and vital sign measurement. With higher sensitivity to visible light in the green part...
ams OSRAM
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Medical Device Multipurpose Adhesive The MD® 1045-M adhesive from Dymax is a light-curable material for medical device assembly. The product is designed to bond glass, SS, ABS, and PC substrates used to assemble prefilled...
Dymax, Headquarters
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Fluorescence Lifetime Imaging Microscopy Module A fluorescence lifetime imaging microscopy (FLIM) module has been added to Renishaw PLC’s inVia™ confocal Raman microscope. The integration can overlay both FLIM and Raman images...
Renishaw PLC, Spectroscopy Products Div.
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Dual-Comb Spectrometer The IRis-C spectrometer from IRsweep utilizes dual-comb spectroscopy and quantum cascade laser frequency combs to offer a combination of high speed, high signal to noise ratio per time, as well as...
IRsweep
Optical Testing System The KVC 821 automatic optical testing system from Kistler provides quality assurance diverse sectors ranging from punching and fastening technology to the medical technology industry. It makes...
Kistler Group
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Extended InGaAs Detectors Hermetically sealed, surface-mount device-packaged 1.7- and 2.6-μm InGaAs PIN ATLAS photodiodes from Marktech Optoelectronics Inc. are designed for spacecraft, aerospace, medical, defense,...
Marktech Optoelectronics Inc.
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