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T Cell Trigger: Sheer Force

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BOSTON, Nov. 3, 2009 – An array of techniques including optical tweezers have been used to find the “switch” that can swiftly change a T cell – a white blood cell that patrols the bloodstream and organs for signs of disease – from jury to executioner. Revealing this “missing link” in immune response to disease may lead to more effective, precisely targeted therapies for cancers and infections. The immune system’s T cells have unique responsibilities. They examine other cells for signs of disease, including cancers or infections. When they encounter another cell, they “frisk” it to determine whether it is normal...Read full article

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    Published: November 2009
    Glossary
    cell
    1. A single unit in a device for changing radiant energy to electrical energy or for controlling current flow in a circuit. 2. A single unit in a device whose resistance varies with radiant energy. 3. A single unit of a battery, primary or secondary, for converting chemical energy into electrical energy. 4. A simple unit of storage in a computer. 5. A limited region of space. 6. Part of a lens barrel holding one or more lenses.
    light
    Electromagnetic radiation detectable by the eye, ranging in wavelength from about 400 to 750 nm. In photonic applications light can be considered to cover the nonvisible portion of the spectrum which includes the ultraviolet and the infrared.
    photonics
    The technology of generating and harnessing light and other forms of radiant energy whose quantum unit is the photon. The science includes light emission, transmission, deflection, amplification and detection by optical components and instruments, lasers and other light sources, fiber optics, electro-optical instrumentation, related hardware and electronics, and sophisticated systems. The range of applications of photonics extends from energy generation to detection to communications and...
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