Intended for protein biochemists and biophysicists, the 469-page volume Spectral Techniques in Proteomics describes spectroscopic tools for use with proteome or subproteome mixtures or with individual/purified proteins studied in parallel. It covers separation techniques that precede electrospray ionization studies as well as matrix-assisted laser desorption/ionization tandem MS (mass spectrometry)/MS-based protein identification. It presents surface-enhanced laser desorption/ionization as a tool that combines separation techniques with MS analysis on the same chip. Studies of protein-ligand interactions using NIR fluorescence, MS and surface plasmon resonance are addressed, as well as developments in isotope-coded affinity tagging strategies and metabolomics. NMR, x-ray crystallography and electron parameter resonance techniques also are described. Daniel S. Sem, ed.; !%CRC Press/Taylor & Francis Group%!, Boca Raton, Fla., 2007; $139.95.