JOEL WILLIAMS, ASSOCIATE EDITOR [email protected]Researchers from the Institute of Photonic Sciences (ICFO) have successfully demonstrated holographic Raman microscopy. The technology is poised to support wide-ranging applications, from live cell and tissue interrogation to, potentially, anti-counterfeiting. Because spontaneous Raman scattering is more than 10 orders of magnitude weaker than fluorescence, the technique is rarely employed. However, Raman can be enhanced dramatically on metal surfaces or in metallic nanogaps to surpass fluorescence response; probes of nanometric surface-enhanced Raman scattering (SERS), therefore, are...Read full articleRelated content from Photonics MediaArticlesRefined Laser Systems Raises $2.9M for Rapid Cancer DiagnosticsBiophotonics technology company and University of Münster spinout Refined Laser Systems has raised €2.7 million ($2.9 million) to develop a prototype intraoperative microscope that the...BioPhotonics Mar/Apr 2023 IssueReusable Substrate Enhances Raman Signal by Factor of 50Materials scientists at Kiel University have developed a photoinduced enhanced Raman spectroscopy (PIERS) method to detect analytes at concentrations one to three orders of magnitude lower than that...Photonics.com 3/31/2023Machine Learning Hones Ability to Image Liver DiseaseA research team at the Tokyo University of Science (TUS) has combined NIR hyperspectral imaging (NIR-HSI) and machine learning to assess lipid content in the liver. The technique enables noninvasive...BioPhotonics Mar/Apr 2024 IssueMicroscopy Method Uses Infrared Light to Image Molecules with Vibrational ContrastThe complementary strengths of fluorescence and vibrational microscopy are combined in a new technique developed at Caltech, which is called bond-selective fluorescence-detected infrared-excited...BioPhotonics Sep/Oct 2023 IssueProductsLasers and Component SpectrometersMetrohm has opened a new webshop for lasers, component spectrometers, and Raman spectroscopy sampling solutions. The new m-oem brand includes four Metrohm companies: Innovative Photonic Solutions...Promoted Content May 2023 IssueMicrospectrophotometerThe FLEX PRO™ from CRAIC Technologies is a microspectrophotometer that combines UV-Visible-NIR microspectroscopy and imaging. It offers features that allow for flexible and precise measurements...BioPhotonics Jan/Feb 2024 IssueSemiconductor Metrology DeviceThe Vista 300 from Molecular Vista Inc. is a nano infrared instrument that can be used in advanced semiconductor process monitoring and defect analysis. The instrument combines an atomic force...Photonics Spectra November 2024 IssueCompact Single-Frequency LasersThe 445-nm and 447-nm TopMode lasers from TOPTICA Photonics AG are single-frequency diode lasers made for high-resolution Raman spectroscopy, microlithography, multi-wavelength digital holography,...Photonics Spectra January 2024 IssuePhotonics Handbook ArticlesVibration Control: Limiting Mechanical NoiseIn general, there are three common approaches to reducing mechanical excitation of photonic systems. The first is identifying the sources of vibration and implementing ways to eliminate or reduce...Photonics HandbookInterferometry: Measuring with LightAn interferometer is an instrument that compares the position or surface structure of two objects. The basic two-beam division of amplitude interferometer components consists of a light source, a...Photonics HandbookSpectroscopy: The Tools of the TradeAll optical spectrometry techniques rely on the measurement of radiant power. The configuration of the instrument varies based on the measurement technique: absorption, emission, luminescence, or...Photonics HandbookSpectroscopy: Mastering the TechniquesThe scope of optical spectroscopic instrumentation is indeed very broad. Many analytical methods rely on the interaction of radiation with matter and are often described in the context of quantum and...Photonics HandbookWhite Papers“Fingerprint” vs Handheld Raman Applications and the Different Optical Filters That Enable ThemRaman spectroscopy is a powerful non-invasive, non-contact tool capable of identifying molecular constituents of samples. Wavelength selective optical filters are used to block the dominant Rayleigh...Photonics.com 4/28/2023Raman SpectroscopyAt Chroma we understand that Raman scattering is a weaker signal that requires much better filters, with steeper edges, in order to isolate the signal of interest. Our Raman filters or sets will...Photonics.com 8/20/2024Multi-Bandpass Filters for FluorescenceLearn how multi-bandpass filters combined with multiple LEDs can enable versatile and compact fluorescence instrumentation.Photonics.com 2/28/2024Choosing a Portable Raman SpectrometerA good portable Raman spectrometer bridges the gap in performance, capability, and size between handheld and benchtop Raman spectroscopy. It enables new point-of-use applications in medicine and...Photonics.com 4/20/2023WebinarsSERS-Based Biophotonics: From Nanotags to Point-of-Care TestingToday, surface-enhanced Raman scattering (SERS) is widely used in the chemical, life, and material sciences. This presentation begins with a short tutorial on the fundamentals of SERS. ...Photonics.com 10/25/2023Enabling Multiplexed and Sensitive Bioanalysis Using SERS and SESORSDetection of specific biomolecules is central to modern biology and to medical diagnostics, where identification of a particular disease is based on biomarker identification. Many detection methods...Photonics.com 1/21/2021Rapid and Effective Large-Area Raman Imaging: Raman Microscopy EvolvesThe last 25 years have seen Raman microscopy evolve from a relatively slow spectroscopic imaging technique, which could take days to image a sample, to an accepted rapid and powerful technique. It is...Photonics.com 1/21/2021Multi-Line Lasers or Laser Combiners: What Solution Is Best for Fluorescence Imaging?Fluorescence imaging is a key technique in both biomedical research and clinical diagnosis. Fluorescence-based microscopy for high-resolution and high-throughput multifluorophore imaging typically...Photonics.com 6/17/2021Photonics Dictionary Termsgold colloid aggregatesGold colloid aggregates refer to clusters or assemblies of gold nanoparticles suspended in a liquid medium. These aggregates are formed when individual gold nanoparticles come together due to various...Photonics Dictionarymultiline laser systemA multiline laser system refers to a type of laser that is capable of emitting multiple discrete wavelengths or spectral lines simultaneously. Unlike single-line lasers, which produce radiation at a...Photonics DictionarysupercontinuumSupercontinuum refers to a broad spectrum of light that spans a wide range of wavelengths, typically from the visible to the near-infrared or even mid-infrared regions of the electromagnetic...Photonics Dictionaryfiber laserA fiber laser is a type of laser in which the active gain medium is an optical fiber doped with rare-earth ions such as erbium, ytterbium, or neodymium. Fiber lasers generate coherent light through...Photonics DictionaryMediaPATHS-UP: The Commercialization of Raman Instrumentation at the Point of Care — With Samuel Mabbott, Michael Matthews, and Cyril SolimanThe Precise Advanced Technologies and Health Systems for Underserved Populations initiative, or PATHS-UP, aims to integrate engineering research and education with technological innovation to...Photonics.com 6/13/2023Andor OEM IntegrationsCutting-edge Innovation √ Unparalleled Quality √ Designed-in Reliability √ Custom Designs √ Andor is the trusted choice for OEM integrations, supplying cameras, spectrographs,...Photonics.com 11/20/2023New Semiconductor Technology Center Comes to Albany and a Flurry of Mergers and AcquisitionsNY CREATES’ Albany NanoTech Complex will be the site of a new National Semiconductor Technology Center. The University of Tokyo has found a way to make Raman spectroscopy 100 times faster. The...Photonics.com 11/7/2024TacticID Mobile Teaser from B&W TekThe TacticID Mobile is the newest addition to B&W Tek's TacticID family of handheld Raman analyzers for safety and security users. The TacticID Mobile is designed for rapid, nondestructive...Photonics.com 5/15/2024Photonics Buyers' Guide CategoriesPicosecond LasersSupercontinuum LasersHeCd LasersRaman Spectrometer Laser SystemsCompaniesOZ Optics LimitedEstablished in 1985, OZ Optics is a leading worldwide supplier of fiber optic components, test equipment and sensors. OZ Optics manufactures its products in three locations, Ottawa (Canada),...Photonics Buyers' GuideAndor TechnologyAndor Technology Ltd is a global developer and manufacturer of high-performance scientific cameras, microscopy systems and spectrographs for academic, government, and industrial applications. Founded...Photonics Buyers' GuideEdinburgh Instruments Ltd.Founded in 1971, Edinburgh Instruments Ltd. is a global provider of sophisticated, state-of-the-art analytical instrumentation for optical spectroscopy. We design and manufacture a range of...Photonics Buyers' GuideFOCtek Photonics Inc.FOCtek provides customers with all types of custom manufactured lenses, Precision Optical Components, Polarizing Optics, Prisms, Filters, Coatings, Optical Systems, Crystals, Nonlinear Crystals,...Photonics Buyers' Guide