ATLANTA, Feb. 15, 2006 -- Using a microphone-inspired probe, researchers at the Georgia Institute of Technology have created a highly sensitive atomic force microscopy (AFM) technology capable of imaging 100 times faster than current AFM, which they say could prove invaluable for nanoscale research such as measuring microelectronic devices, observing fast biological interactions on the molecular level and even creating movies of molecular interactions in real time. FIRAT simultaneously captures a variety of material properties from just one touch, including (from upper left to right) topography, adhesion energy, contact time and stiffness. (Images: Georgia Tech)Not only is FIRAT (force-sensing integrated readout and active tip) much faster than AFM (the current workhorse of nanotech), it can capture other measurements never before possible with AFM, including material property imaging and parallel molecular assays for drug screening and discovery. FIRAT could also speed up semiconductor metrology and even enable fabrication of smaller devices. It can be added with little effort to existing AFM systems for certain applications. “I think this technology will eventually replace the current AFM,” said Levent Degertekin, head of the project and an asscoiate professor in the Woodruff School of Mechanical Engineering at Georgia Tech. “We’ve multiplied each of the old capabilities by at least 10, and it has lots of new applications.” FIRAT solves two of AFM’s chief disadvantages as a tool for examining nanostructures -- AFM doesn’t record movies and it can’t reveal information on the physical characteristics of a surface, said Calvin Quate, one of the inventors of AFM and a professor at Stanford University. “It is possible that this device provides us with the ‘ubiquitous’ tool for examining nanostructures,” Quate stated. Levent Degertekin holds the new FIRAT next to the much larger AFM part it replaces.Key to this dramatic increase in speed and capabilities is a completely new microphone-inspired probe. Current AFM scans surfaces with a thin cantilever with a sharp tip at the end. An optical beam is bounced off the cantilever tip to measure the deflection of the cantilever as the sharp tip moves over the surface and interacts with the material being analyzed. FIRAT works a bit like a cross between a pogo stick and a microphone. In one version of the probe, the membrane with a sharp tip moves toward the sample and just before it touches, it is pulled by attractive forces. Much like a microphone diaphragm picks up sound vibrations, the FIRAT membrane starts taking sensory readings well before it touches the sample. And when the tip hits the surface, the elasticity and stiffness of the surface determines how hard the material pushes back against the tip. So rather than just capturing a topography scan of the sample, FIRAT can pick up a wide variety of other material properties. “From just one scan, we can get topography, adhesion, stiffness, elasticity, viscosity -- pretty much everything,” Degertekin said. For a regular AFM to detect the features of the object, the actuator must be large enough to move the cantilever up and down. The inertia of this large actuator limits the scanning speed of the current AFM. But FIRAT solves this problem by combining the actuator and the probe in a structure smaller than the size of a head of a pin. With this improvement, FIRAT can move over sample topography in a fraction of the time it takes AFM to scan the same area. An image of the FIRAT probe, which is smaller than the head of a pinGeorgia Tech researchers have been able to use FIRAT with a commercial AFM system to produce clear scans of nanoscale features at speeds as high as 60 Hz (or 60 lines per second). The same system was used to image the topography as well as elastic and adhesive properties of carbon nanotubes simultaneously, which is another first. The researchers say that FIRAT’s new speed and added features may open up many new applications for AFM. For instance, FIRAT is capable of scanning integrated circuits for mechanical and material defects. And in biomolecular measurement applications, FIRAT can scan the surface quickly enough for a researcher to observe molecular interactions in real time. “The potential is huge. AFM started as a topography tool and has exploded to many more uses since. I’m sure people will find all sorts of uses for FIRAT that I haven’t imagined,” Degertekin said. FIRAT will be available for certain applications immediately, while others may take a few years, he said. The research, funded by the National Science Foundation and the National Institutes of Health, appeared in the February issue of Review of Scientific Instruments. For more information, visit: www.gatech.edu