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Moving Raman Spectroscopy into the Clinic

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Thomas Mayerhöfer,1 Christoph Krafft,1 Ute Neugebauer1,2 and Jürgen Popp1,2,3
1Leibniz Institute of Photonic Technologies
2Center for Sepsis Control and Care, University Hospital Jena
3Institute of Physical Chemistry, Friedrich Schiller University

Raman spectroscopy’s molecular sensitivity makes it promising for clinical applications: It can identify pathogens much faster than current methods, investigate circulating tumor cells, help surgeons distinguish tumors from healthy tissue and identify the chemical nature of cardiovascular plaques and evaluate their severity. Today’s aging population presents a great challenge: ensuring affordable and sustainable health care systems. As the number of people over 65 grows, society faces an increase in age-related diseases. Accordingly, the number of cases of macular...Read full article

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    Published: June 2014
    Glossary
    pathogen
    A pathogen is a biological agent, such as a virus, bacterium, fungus, protozoan, or parasite, that causes disease in its host organism. Pathogens have the capability to invade host tissues, replicate, and disrupt normal physiological functions, leading to the development of an infection or disease. Pathogens can infect various organisms, including humans, animals, plants, and even other microorganisms. They can spread through various means, such as direct contact with an infected...
    raman scattering
    Raman scattering, also known as the Raman effect or Raman spectroscopy, is a phenomenon in which light undergoes inelastic scattering when interacting with matter, such as molecules, crystals, or nanoparticles. Named after Indian physicist Sir C. V. Raman, who discovered it in 1928, Raman scattering provides valuable information about the vibrational and rotational modes of molecules and materials. Principle: When a photon interacts with a molecule, most of the scattered light retains...
    AmericasBiophotonicsbrain tumorcardiovascular diseasechemicalsEuropeFeaturesFiltersImagingMaterialsMicroscopyOpticspathogenRaman scatteringSensors & DetectorsSHGspectroscopysurgical microscopeTPEFmolecular sensitivity

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