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FRET Offers Real-Time Look at HIV Infection Process

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Scientists can now study the motion of HIV proteins on the surface of the virus, opening new possibilities for fighting the disease. A team at Weill Cornell Medical College used single-molecule fluorescence resonance energy transfer (smFRET) imaging to get real-time view of how the proteins attack and infect human immune cells. “Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells,” said Dr. Scott Blanchard, an associate professor...Read full article

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    Published: October 2014
    Glossary
    fluorescence
    Fluorescence is a type of luminescence, which is the emission of light by a substance that has absorbed light or other electromagnetic radiation. Specifically, fluorescence involves the absorption of light at one wavelength and the subsequent re-emission of light at a longer wavelength. The emitted light occurs almost instantaneously and ceases when the excitation light source is removed. Key characteristics of fluorescence include: Excitation and emission wavelengths: Fluorescent materials...
    Research & TechnologyImagingBiophotonicsAmericasHIVAIDSWeill Cornell Medical Collegefluorescencesingle-molecule fluorescence resonance energy transfersmFRETFRETScott BlanchardBioScan

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