A rapid-fire Hot Topics session featuring talks on the latest in biomedical optics, from live analysis of embryonic development to deep learning-enabled optics, will be a centerpiece at SPIE BiOS — part of Photonics West 2022 — to be held Saturday and Sunday, January 22-23, at the Moscone Center in San Francisco. The event will take place in person once again and will feature a host of photonics companies offering a variety of technology for health and life science applications in its companion exhibition. Jennifer Barton of the University of Arizona and Wolfgang Drexler of the Medical University of Vienna will chair the event. “We have terrific speakers lined up for our Hot Topics, Neurotechnologies, and Nano/Biophotonics plenaries,” said Marilyn Gorsuch, SPIE senior director of technical programs. “Our BiOS exhibitors are excited to come back together to connect with attendees and showcase their products and services. But most of all, we are looking forward to connecting face to face with our photonics community and providing opportunities for networking and collaboration to support the world-class biophotonics research and applications, industry developments, and technology innovations that are presented at Photonics West and BiOS.” SPIE Photonics West 2022 and BiOS will return to an in-person format. Attendees will hear from biophotonics experts and see the latest products developed for imaging, diagnostics, and therapeutics. Sergio Fantini of Tufts University will facilitate Hot Topics, which will take place on Saturday. The event will include insights into topics such as “Holographic imaging and its bioapplications,” “Tissue optical clearing imaging: from in vitro to in vivo,” and “Cerebral health in a heartbeat.” Application tracks Sessions at the BiOS conference will be divided into six tracks: Photonic Therapeutics and Diagnostics. This session will feature topics such as applications of light in cardiology, visualizing and quantifying drugs in tissue, and molecular-guided surgery. Brian Jet-Fei Wong of the Beckman Laser Institute and Medical Clinic at the University of California, Irvine and Eva Sevick of the University of Texas Health Science Center will co-chair. Neurophotonics, Neurosurgery, and Optogenetics. This session will feature topics such as clinical and translational neurophotonics, neural imaging and sensing, and optogenetics and optical manipulation. Elizabeth Hillman of Columbia University and Anna Devor of Boston University will co-chair. Clinical Technologies and Systems. This session will feature topics such as optical coherence tomography and coherence domain optical methods in biomedicine; optics and biophotonics in low-resource settings; and microfluidics, bioMEMS, and medical microsystems. Tuan Vo-Dinh of Duke University and Anita Mahadevan-Jansen of Vanderbilt University will co-chair. Tissue Optics, Laser-Tissue Interaction, and Tissue Engineering. This session will feature topics such as photons plus ultrasound: imaging and sensing, biophotonics and immune response, and polarized light and optical angular momentum for biomedical diagnostics. E. Duco Jansen of Vanderbilt University and Jessica Ramella-Roman of Florida International University will co-chair. Biomedical Spectroscopy, Microscopy, and Imaging. This session will feature topics such as multiphoton microscopy in the biomedical sciences, single-molecule spectroscopy and superresolution imaging, and advancements in terahertz biomedical imaging and spectroscopy. Ammasi Periasamy of the University of Virginia and Daniel Farkas of the University of Southern California will co-chair. Nano/Biophotonics. This session will feature topics such as nanoscale imaging, sensing, and actuation for biomedical applications; plasmonics in biology and medicine; and frontiers in biological detection: from nanosensors to systems. Paras Prasad of the University of Buffalo and Ewa Goldys of the University of New South Wales will co-chair. Best paper awards Researchers and scientists in a variety of burgeoning optical specialties will be honored by SPIE for best papers. BiOS best paper awards are sponsored by companies such as Boston Scientific, Johnson & Johnson, and Seno Medical. Categories include Advanced Photonics in Urology; Multiscale Imaging and Spectroscopy; the Pascal Rol Award 2022 — Ophthalmic Technologies; Microfluidics, BioMEMS, and Medical Microsystems; Photons Plus Ultrasound: Imaging and Sensing; the JenLab Young Investigator Award — Multiphoton Microscopy in the Biomedical Sciences; the PicoQuant Young Investigator Award — Single Molecule Spectroscopy and Superresolution Imaging; the Prizmatix Young Investigator Award — Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications; and Ocean Insight Young Investigator Award — Colloidal Nanocrystals for Biomedical Applications. BiOS Expo The BiOS Expo, to be held on both days of the conference, will include over 100 companies displaying their equipment, components, and systems for microscopic imaging, biosensors, and laser therapy. Companies bringing the latest technology in the optics market will include Applied Scientific Instrumentation, Carl Zeiss Spectroscopy, Coherent, Edmund Optics, Hamamatsu, HÜBNER Photonics, Innovative Photonic Solutions, JENOPTIK Optical Systems, Lumencor, Mad City Labs, MKS Instruments, SCANLAB America, Teledyne Imaging, and TOPTICA Photonics. BioPhotonics magazine and Photonics Media will also have a booth at the expo. Attendees of the event will be expected to wear masks and supply proof of vaccination. For more information about the show, visit www.spie.org.