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Features
Light Source Helps Endoscopes Get Smaller and Smaller
Xenon light sources represent the benchmark for medical illumination,but they cannot couple light through the small channels used for microendoscopes. Significant research has been undertaken to improve imaging sensors for endoscopy, but little work has been done to maximize the performance of the light sources and the light delivery system required to support them. Xenon light systems suffer from weak light delivery through small fibers in spite of continuous sensitivity improvements to im...
BioPhotonics, September 2012
Multimodal Label-Free Imaging Drives Biomedical Research
Label-free noninvasive, nondestructive optical microscopy using multiple simultaneous techniques allows researchers to observe diverse life processes in real time. Optical microscopy is a powerful tool in bioscience research, allowing researchers to...
BioPhotonics, September 2012
New Glass Fibers Widen Range of Medical Lighting Applications
Optical fibers with higher light transmission and longer life spans offer interesting new solutions for meeting the growing demand for higher quality lighting in medicine. New glass optical fibers offer longer lifetimes and higher light...
BioPhotonics, September 2012
The Age of the Tricorder
The medical device of the future is already here. The Star Trek television series and movies have proved remarkably prescient in anticipating future technologies – from flip phones to iPads – decades before they appeared in...
BioPhotonics, September 2012
From Waveform to Form Factor: Designing Laser-Based Medical Devices Has an Aesthetic All Its Own
When is a medical device a useful piece of equipment, and when is it an art form, pleasing to the eye and to the touch? If made with a careful eye to the needs of clinicians and patients alike, it can be both. Innovative device design can be an...
BioPhotonics, July 2012
In Vivo Studies Promise to Advance Diagnosis
Techniques that leave cell systems and organisms intact could provide a means to screen whole populations for disease less invasively and less expensively than traditional tests. In vivo optical techniques provide a wealth of information about the...
BioPhotonics, July 2012
Photocoagulation Refinements Are Decimating Birthmarks
(but Improving Birth Outcomes)
Precisely applied heat from the touch of a laser not only can hide blemishes, but can also save lives. For many, laser surgery brings to mind highly refined incisions made by coherent light pulses. Cutting, however, is not the only action a laser...
BioPhotonics, July 2012
Superresolution Microscopy Images Neurons on the Nanoscale
Recent advances allow superresolution microscopy to deliver on its promise of using focused light to provide glimpses of the inner workings of living organisms, resolving structures on the scale of tens of nanometers. The past decade witnessed a...
BioPhotonics, July 2012
Advanced Optics Deliver Drugs with IR Light
Biocompatible microparticles allow noninvasive, optically driven on-demand controlled release of methotrexate to treat psoriasis. Drugs are conventionally delivered orally or intravenously – but “conventional” does not always mean...
BioPhotonics, May 2012
CW DPSS Lasers Make STED Microscopy More Practical
Until now, stimulated emission depletion (STED) microscopy typically had been realized with the use of rather large and complex laser systems. But a setup for STED microscopy using a compact and low-noise 0.5-W, 660-nm, single-frequency...
BioPhotonics, May 2012
Fresh Ways to Shoot Faster Pictures
Muscles can move quickly – and individual proteins move even faster. So how do you capture such blazingly fast events? In the study of biological systems – cell biology being the premier example – nonlinear microscopy techniques...
BioPhotonics, May 2012
Improving Lives Through Spectroscopic Analysis
Noninvasive spectroscopy is aiding clinicians in the treatment of brain trauma, cancer and more. Measuring the amount of oxygen in blood carried by veins, arteries and even capillaries is a common diagnostic technique in hospital labs around...
BioPhotonics, May 2012
Lasers Match Performance to Application
OPSL technology has powered a paradigm shift in orange lasers for use in the life sciences by enabling wavelength and power to be customized to exactly match specific applications, instead of the other way around. For many years, applications in...
BioPhotonics, May 2012
Dynamic Phase-Shifting Microscopy Tracks Living Cells
The ability to instantaneously measure live cells – and follow motions and processes over time – helps researchers study dynamic cell behavior. Using harmless light levels – and without contrast agents – a dynamic...
BioPhotonics, April 2012
Maldi-MS Making a Strong Comeback
From cancer diagnosis and prognosis to the effects of applying medical leeches, the applications of Maldi imaging are growing. Higher throughput and a wider choice of instruments such as solid-state UV lasers have greatly improved the analytical...
BioPhotonics, April 2012
Nanoparticle Tracking Analysis Characterizes Biomaterials
Biomaterial characterization at the nanoscale is gathering interest, as a better understanding of properties such as particle size or number may provide new ways to look at nanotoxicology or provide pathways to the development of early diagnostic...
BioPhotonics, April 2012
OCT Moves from Clinic to OR to . . . Home?
Optical coherence tomography has proved its worth in the physician’s office, but now it wants to make inroads into the surgical suite as well – and possibly beyond. Optical coherence tomography, or OCT, is a rapid, noncontact,...
BioPhotonics, April 2012
Collaboration Sparks Nerve-Fiber “Turn Signal” Discovery
Global, multidisciplinary cooperation has led to a significant advance in neuroscience – a way to guide growth in neurons – that ultimately could have big implications for nerve disorders. The human brain’s billions of neurons make...
BioPhotonics, March 2012
European Companies Win Big
The winners of the 2011 Prism Awards for Photonics Innovation represented an intriguing mix of European and US-based small companies and established businesses. The annual international competition, sponsored by Photonics Media and SPIE, honors...
Photonics.com, March 2012
Moving Noninvasive Cancer Imaging into the Clinic
So you came up with this great idea for a medical device for cancer imaging, and even found a way to make it work. Now what? Several researchers involved with coherence imaging technologies discuss the challenges of clinical translation. You have...
BioPhotonics, March 2012
PDT for Cancer Depends on Improved Photosensitizers
Photodynamic therapy could be the future of cancer treatment – that is, once the photoactive chemicals behind it start doing their jobs better. Photodynamic therapy (PDT) is proving to be a more than viable option for cancer treatment....
BioPhotonics, March 2012
Transoral Laser Microsurgery Fights Laryngeal Cancer
Thanks to laser surgery refinements, “your life or your voice” is a choice fewer people in the world have to face. In the US alone, 10,000 people are diagnosed each year with laryngeal carcinoma, according to the American Cancer Society....
BioPhotonics, March 2012
3-D Microscopy Goes Deeper and Deeper
New systems take researchers inside the workings of tissue, cells, organelles The biomedical industry is constantly involved in biological research and development, not only examining the basic functions of cells and tissues to find targets for...
BioPhotonics, February 2012
Piezoelectric Actuation Adds Capabilities for Microscopy
Microscopy is a broad field – and it is getting broader every week, as novel imaging techniques are brought to bear to illuminate the nanoscale world. These techniques are enabled and assisted by the application of piezoelectric positioning...
BioPhotonics, February 2012
SPR Provides a Boost to Drug Discovery and Development
Surface plasmon resonance techniques show promise as the new standards of drug discovery, especially for treating cancer. In the realm of drug discovery, the hunt is ever on for new combinations of analytes and receptors. Respectively, these are the...
BioPhotonics, February 2012
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