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Wednesday, January 24, 2018
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Monthly newsletter focusing on how light-based technologies are being used in the life sciences. Includes news, features and product developments in lasers, imaging, optics, spectroscopy, microscopy, lighting and more. Manage your Photonics Media membership at Photonics.com/subscribe.
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sponsor
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MUSE: Simple Slide-Free Microscopy
Even in this era of molecular medicine, conventional light microscopy remains the principal contributor to cancer diagnostics and also serves to guide surgical procedures, monitor disease activity and follow therapy responses over time. Although pathologists don’t like to admit it, the optical principles that underlie their microscopes date back, largely unchanged, to the 18th century. Moreover, for these microscopes to be useful, properly prepared tissue samples mounted onto glass slides are a prerequisite, and the methodology for the necessary histological processing has itself not changed significantly since the end of the 19th century. Both aspects of tissue diagnostics are due for a refresh.
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Endospectroscopic Imaging Takes Optical Biopsies to the Next Level
Spectroscopy has the potential to provide pathologists with fast in vivo tissue characterization to determine tumor type and grade and to delineate tumor margins. However, extending the applicability of microspectroscopy to in vivo imaging requires suitable optical fiber probes for an endoscopic inspection of difficult-to-access body regions. The engineering process is challenging. Besides the miniaturization of microscopy, it requires innovative scanning, excitation light delivery and signal collection, as well as robust and alignment-free light sources.
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Terahertz Imaging Takes Aim at Dermatology and Dentistry
Thanks to advances that cross several disciplines, the terahertz community is making its mark in medical research. The first terahertz image was taken at the AT&T Bell Laboratories more than 20 years ago in 1995. The astonishingly clear image of the inside of a packaged semiconductor integrated circuit brought immense attention to terahertz imaging for applications ranging from security, astronomy, remote sensing and chemical sensing to biomedical imaging.
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Eight Bright Solid-State Light Sources
Lumencor Inc.
Lumencor’s new SPECTRA III Light Engine® is here, with
- Eight independent solid-state light sources
- Spectrally optimized DAPI, CFP, GFP, YFP, Cy3, mCherry, Cy5 and Cy7 excitation
- ~0.5W per output channel from a standard liquid light guide
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Dual Light Sheet Microscopy
Applied Scientific Instrumentation Inc.
ASI’s Dual Selective Plane Illumination Microscopy for Cleared Tissue (ct-dSPIM) is one of many light sheet microscope configurations possible using our modular components. This flexible and easy-to-use Selective Plane Illumination Microscopy (SPIM) implementation allows for dual views of large samples.
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4-Color Laser Engine Ideal for Confocal Microscopy
TOPTICA Photonics Inc.
TOPTICA's iChrome CLE is a compact laser engine that combines four laser lines in one box. All integrated colors are provided via one polarization-maintaining single-mode fiber. It is available with 405, 488, 561 and 640 nm and more than 20 mW guaranteed output power after the fiber each.
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Ultrasensitive Chip-Based Optical Sensors
An optical whispering gallery mode resonator can spin light around the circumference of a tiny sphere millions of times, creating an ultrasensitive microchip-based sensor for multiple applications.
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A wireless handheld spectrometer that is smartphone-compatible could make it easier and more economical to acquire spectral images of everyday objects and in the future could be used for point-of-care medical diagnosis in remote locations.
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Scientists have demonstrated a time-resolved spectroscopy technique that enables the study of very fast processes in samples on the femtosecond (fs) time scale without the need for an fs laser or a complex detection system.
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Optics and Lighting Solutions for Machine Vision
Tue, Mar 20, 2018 1:00 PM - 2:00 PM EDT
A crucial first step in any good machine vision application is developing the right optics and lighting for the application. This webinar will address the basic principles and methods of machine vision optics and lighting and review advances in methods and components that have made machine vision easier to implement in recent years. Sponsored by Smart Vision Lights and Euresys S.A.
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Features
Biophotonics Inspired by Nature; Nonlinear Optical Imaging; Fiber Optic Light Sources for Surgery; UV Microscopy
Photonics Media is currently seeking technical feature articles on a variety of topics for publication in our magazine BioPhotonics. Please submit an informal 100-word abstract to Associate Managing Editor Marcia Stamell at [email protected] or use our online submission form www.photonics.com/submitfeature.aspx.
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