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Microscopy Tech Pulse (10/18/2022)

Microscopy Tech Pulse

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Tuesday, October 18, 2022

Microscopy Tech Pulse is a special edition newsletter from Photonics Media and Mad City Labs covering key developments in microscopy technology.

Photoacoustic System Enables Real-Time Neurovascular Imaging
A photoacoustic imaging tool accommodates the need for speed and comprehensive detail in neurovascular imaging. The imaging modality enables an approach to visualize whole-brain hemodynamics and oxygenation in real time. It also tracks fast pathophysiological activities at the micro-vessel level. The approach breaks speed and resolution barriers in brain imaging technologies, and could lead to insights into stroke, dementia, and acute brain injury.

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Mad City Labs Inc. - Is a DIY Microscope for you?
Recently, it has become very popular for researchers to explore building their own microscopes. Budgetary and technical specifications are among the motivations for this approach. However, there is a spectrum of solutions within the DIY microscope space. This article helps readers determine whether a do-it-yourself (DIY) microscope is the appropriate solution for their application and how to procure the right instrument.

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Nanotechnology, Deep Learning Help Detect Pediatric Tuberculosis
A technique for diagnosing tuberculosis (TB) in children takes advantage of the optical properties of gold nanoparticles to detect the disease. The technique uses an artificial intelligence (AI) algorithm to enhance the sensitivity of the test, as well as low-magnification dark-field microscope (DFM) image analysis.

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Quantum Advancement Combines Free Electrons and Photons
A collaboration between Swiss and German researchers demonstrated the generation of electron-photon pair states for the first time in a controlled way, using integrated photonic circuits on a chip. Using a new technique, they precisely detected the involved particles. The experiment could enable quantum-enhanced electron microscopy and adds free electrons to the toolbox of quantum technologies.

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Internal Reflection-Based Microscopy Images Single Protein
A team from Arizona State University has introduced evanescent scattering microscopy (ESM), a label-free method for sensitive imaging of biomolecules, including proteins. The single-molecule microscopy technique is based on total internal reflection, an optical phenomenon that occurs when light passes from a high-refractive medium, like glass, into a low-refractive medium, like water.

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