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BioPhotonics - Sep/Oct 2023


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Features
Fiber Optic Probes Help Customize Spectroscopic Diagnosis Diffuse reflection spectroscopy and fluorescence spectroscopy are having a major effect in medicine and the life sciences, with expanding application in physics, chemistry, biology, and medicine. And...
Illumination Advancing Fluorescence Microscopy in Life Sciences, Medical Realms In many academic research and medical settings, microscopy and imaging have transitioned from using traditional lamp illumination, such as mercury and Xenon lamphouses, to solid-state LED...
QCL-IR Powers Photoacoustic Spectroscopy in Translational Medicine Mid-infrared (MIR) optoacoustic spectroscopy is a well-established technique that is currently being leveraged with modern instrumentation to push boundaries in life sciences research and medical...
Build Versus Buy: Considerations in SD-OCT System Design Many researchers and product developers using spectral-domain optical coherence tomography (SD-OCT) for biomedical research and clinical treatment choose to build their own system. This requires...
Editorial
Real smarts boosts AI value Scientists in the biophotonics community have long recognized the value of artificial intelligence (AI) and machine learning in diagnostics, ever since the creation of a computer-assisted detection model to highlight areas of concern in images and the FDA’s subsequent approval of this approach for mammography in the 1990s. Software programs have since catapulted radiomics — the...
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BioPhotonics Conference Highlights Effective System Design and Application in Research and Medicine Leading practitioners across the spectrum of innovation in biophotonics technology will spotlight the field’s rapidly advancing landscape in the BioPhotonics Conference taking place October 24-26. The online showcase features sessions from technology developers and instrument manufacturers spanning the industry, academia, and research communities. Luminary figures, as well as startup companies...
BioScan
Light-Activated Biomimetic Gel Offers Potential for Corneal Repair Tens of millions of people around the world suffer from corneal diseases, with only a small fraction eligible for corneal transplantation. In a recent study, researchers at the University of Ottawa...
ams OSRAM Details Business Restructure Along with unveiling its second-quarter earnings, ams OSRAM announced it will eliminate its passive optical components portfolio, among others, as part of a strategic realignment. The company plans...
Reconceptualized OCT Method Targets Cancer Diagnoses An international team of researchers has made an advancement to the technique of optical coherence tomography (OCT) that holds implications for ophthalmology, dermatology, cardiology,and the early...
Optofluidic Micromanipulations Show Aptitude in Laser Biomedicine Techniques for micromanipulation, including those that rely on optofluidics, are widely adopted for applications in the life sciences, materials science, and colloidal physics. These techniques...
At-Home Biosensing Platform Developer Gets $27M Investment SiPhox Health, an MIT spinout developing laboratory-grade home health testing using silicon photonics technology, has secured $27 million in financing — $10 million in seed financing and $17...
Brain Imaging, Image Reconstruction Combine in a Single Workflow Scientists at Institute of Science and Technology Austria (ISTA) have developed an imaging technology to analyze live brain tissue at a scope and spatial resolution that, according to the...
Multimodal Microspectroscopic Approach Targets Cancer’s Spread in Tissue To improve the study of the pathological processes of cancer cells, researchers at Beijing Institute of Technology combined divided-aperture laser differential confocal microscopy with Raman...
Microscopy Method Uses Infrared Light to Image Molecules with Vibrational Contrast The complementary strengths of fluorescence and vibrational microscopy are combined in a new technique developed at Caltech, which is called bond-selective fluorescence-detected infrared-excited...
Optogenetics Reveals Relationship Between Brain and Gut Health The brain-gut connection is known to influence hunger and mood, and it has also been associated with neurological and other disorders. To explore the signaling that occurs between these two organs,...
In-Ear Wearable Measures Blood Flow to the Head Prior to Fainting Digital health company STAT Health has unveiled a 24/7 in-ear wearable that uses optical sensors to measure blood flow to the head to better understand symptoms such as dizziness, brain fog,...
Near-Infrared Wavelength Specificity Yields Phototherapy Insights Transcranial photobiomodulation (tPBM) is an emerging form of light therapy that uses LEDs or low-intensity lasers that emit near-infrared (NIR) light to stimulate the brain. Although tPBM is in the...
DNA-Barcoded Fluorescence Imaging Illuminates Core Cell Components Since many core components of cells — like DNA, RNA, proteins, and lipids — are just a few nanometers in size and substantially smaller than the resolution limit of traditional light...
3 Questions
Three Questions with Holger Schmidt Holger Schmidt, Ph.D., distinguished professor of electrical and computer engineering and the Narinder Singh Kapany chair of optoelectronics in the Baskin School of Engineering at UC Santa Cruz, discusses the application of signal processing techniques to a newly developed optofluidic chip-based biosensor.
BioOpinion
Responsible AI Can Enhance Life Sciences Productivity According to a recent survey conducted by Huma.AI, the majority of medical affairs leaders and professionals see potential for Chat Generative Pretrained Transformer (ChatGPT)-like technology to be applied at life sciences companies to improve efficiency and accuracy in a variety of functions. In addition, they believe a generative AI platform could improve patient outcomes in health care...
Postscripts
Imaging helps call out a 'monster' Nearly 70 years ago, an unusual fossil found in Mazon Creek Lagerstätte in Grundy County in Illinois spawned a decades-long dispute about what type of marine creature the Tully monster is. Discovered by fossil hunter Francis Tully in the 1950s, the ~15 cm-long, soft-bodied Tullimonstrum gregarium has stalked eyes and a long nose and is unlike any other species on the fossil record. A debate began...
Products
Miniature Spectrometer The MiniRaman miniature spectrometer from Opton Laser International measures 25 × 30 × 105 mm and weighs 0.5 kg. The device features an integrated, patented reference channel, enabling automatic wavelength and intensity calibration. The spectrometer covers the fingerprint region from 400 to 4500 cm-1 with a resolution of 10 to 15 cm-1. Reducing signal-to-noise allows Raman...
Opton Laser International SA
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Upright Microscope The ECLIPSE Ui integrated microscope-based viewing system from Nikon Instruments Inc. is designed for clinical and pathological observation. The system provides a digital user experience,...
Nikon Instruments Inc.
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AI-Powered Microscope Software Leica Microsystems’ Aivia 12 software provides AI-powered image analysis. It incorporates the Cellpose deep learning model to tackle dense neuron images, improving soma detection by as much as...
Leica Microsystems GmbH
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IR Microscope The AIMsight Infrared Microscope from Shimadzu Scientific Instruments Inc. offers automated analysis functions and an enhanced wide field camera for efficient microsample analysis. The...
Shimadzu Scientific Instruments Inc.
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Nanoparticle Tracking Analysis System The NanoSight Pro nanoparticle tracking analysis (NTA) system from Malvern Panalytical BV simplifies nanomaterials characterization through machine learning. The system provides fast and...
Malvern Panalytical BV
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Tunable Pulsed Nanosecond Laser The Peacock XT 355 from Quantel Laser is a tunable pulsed nanosecond laser source in the visible and NIR wavelengths. The device includes a Q-smart series Nd:YAG laser pumping an optical...
Quantel laser by Lumibird
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Microspectrophotometer The 2030XL PRO™ Microspectrophotometer from CRAIC Technologies Inc. is a high-performance instrument for advanced materials analysis. The device offers advanced spectroscopic capabilities...
CRAIC Technologies
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Slide Imaging System The SLIDEVIEW™ DX VS-M1 whole slide imaging system from Evident Scientific is a digital pathology solution for efficient diagnoses. The device delivers high-quality slide images at high...
Evident
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Optical Stereo Microscopes The third-generation range of Mantis ergonomic optical stereo microscopes from Vision Engineering Ltd. feature improved optics for hand-to-eye coordination and depth perception. The microscopes...
Vision Engineering Inc.
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Microscopy Software Suite SIX software from WITec GmbH is designed for Raman and correlative measurement control, data acquisition, and post-processing. The software offers multiple user profiles, regulatory compliance...
Oxford Instruments WITec
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Pump Laser Furukawa Electric has extended the normal C-band range of the FRL1441U Series pump laser to enable applications in the S-band and L-band of high output power, low power consumption for Raman...
Furukawa Electric Co. Ltd.
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