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BioPhotonics - Nov/Dec 2023


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Features
Multiphoton Microscopy Evolves with the Aid of Laser Systems Multiphoton excitation (MPE) microscopy has successfully transitioned from the demonstration of its potential that took place more than 30 years ago to a powerful imaging method used throughout the...
Fluorescence Imaging Could Guide Tissue Infection Diagnosis and Treatment Necrotizing soft-tissue infections (NSTIs) are aggressive and rapidly advancing infections with a mortality rate between 20% and 30%. In the mainstream media, this disease process is more commonly...
Illuminating the Unseen: Data at Depth with Light-Sheet Fluorescence Microscopy Light-sheet fluorescence microscopy, also called single plane illumination microscopy (SPIM) is a noninvasive 3D imaging method that employs a sheet of light to illuminate a thin plane of a specimen....
Live-Cell Imaging Follows Early Signs of Mutation and Disease Scientists are increasingly turning to live-cell imaging to track changes at the developmental stage of life, which is vital for the advancement of cellular biology, and to grow and monitor...
Editorial
Cellular analysis goes live For biomedical researchers working with cell culture, an accurate, real-time reading of progression and confluency (density) in cell populations is their ultimate objective. The information gleaned from imaging these samples is valuable in understanding cell proliferation and functionality at its most fundamental stages as well as tracking specific therapeutics in the tissue of patients. If...
Show Preview
SPIE BiOS Elevates Single-Cell Investigations in Science and Medicine The SPIE BiOS Expo will once again kick off Photonics West 2024, with an exhibition of notable companies in biomedical optics as well as numerous sessions highlighting research during the weekend of Jan. 27 and 28 at the Moscone Center in San Francisco. Companies will offer insights into miniaturized optical components at work in photoacoustic imaging and multiphoton microscopy, and virtual...
BioScan
Label-Free Imaging Shows Dynamics of Intracellular Cargo Transport Until now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of photobleaching and the visual isolation of cellular features from their environment limit the modality’s ability to glean information about the process and how it is conducted within the crowded...
Nobel Prize in Chemistry Recognizes Quantum Dot Pioneers Moungi Bawendi, Louis Brus, and Alexei Ekimov have been awarded the 2023 Nobel Prize in chemistry for the discovery and development of quantum dots, which are nanoparticles small enough that their...
Single-Cell Analysis Optofluidics Tool Delivers on Demand An on-demand optical system for exporting target droplets from a static droplet array (SDA) provides a simple way to export specific cells or analytes for analysis without compromising efficiency or...
Excelitas Technologies to Acquire Heraeus Noblelight Excelitas Technologies has signed a definitive agreement with Heraeus Group to acquire the Heraeus Noblelight business. Heraeus Noblelight specializes in the development and manufacture of specialty...
Photoacoustic Microscopy Method Delivers Higher Sensitivity A multispectral, super-low-dose photoacoustic microscopy (SLD-PAM) system developed by City University of Hong Kong (CUHK) achieves significantly higher sensitivity than traditional optical...
£520 million to add three beamlines to U.K.’s National Synchrotron A nearly £520 million ($648.3 million) investment in the U.K.’s national synchrotron, Diamond Light Source, will lead to the implementation of three new flagship beamlines, as well as...
Imec Spinout Axithra Raises $10M for Chip-based Raman Tech Axithra, a spinout of imec and Ghent University, has raised €10 million ($10.7 million) in a seed round to develop a chip-based Raman spectroscopy platform to monitor drug concentration in the...
SPIE Unveils New Biophotonics Journal SPIE will launch Biophotonics Discovery, the 15th publication from the society. The journal will serve as a peer-reviewed outlet for research presented at the Photonics West BiOS Symposium, SPIE...
Apollon, MIT Collaborate on Noninvasive Glucose-Monitoring Tech Seoul-based medical technology startup Apollon Inc. will collaborate with MIT’s Laser Biomedical Research Center (LBRC) to develop and conduct clinical trials of noninvasive continuous glucose...
SPIE Elects Rochester’s Julie Bentley into Presidential Chain University of Rochester professor Julie Bentley has been elected to serve as the 2024 vice president of SPIE. With her election, Bentley joins the SPIE presidential chain and will serve as...
Bruker Enters into New Research Space with PhenomeX Acquisition Bruker has signed a definitive agreement to acquire functional cell biology company PhenomeX for $1 per share in an all-cash transaction. The proposed acquisition values PhenomeX at a total equity of...
Evident Corp. Appoints Leadership Team Evident Corp. appointed William Wesley “Wes” Pringle CEO and Hiroyuki Yoshimoto president and COO as the life science and industrial microscopes manufacturer reworks its leadership group....
Light-Activated Metal Particles Deliver Targeted Cancer Treatment A research group from Japan Advanced Institute of Science and Technology (JAIST) developed light-activatable, liquid metal (LM) nanoparticles for cancer diagnosis and treatment via...
Optical Measurements Combine for Early Metastasis Detection Diffuse in vivo flow cytometry (DiFC), an optical technique developed at Northeastern University, enables fluorescence detection of tumor cells circulating in the bloodstream. It is a promising...
Near-IR Biosensors Use DNA Anchors to Target Range of Molecules To build a flexible sensor for optically detecting a range of viruses and bacteria, a group of researchers from Ruhr University Bochum (RUB), the Fraunhofer Institute for Microelectronic Circuits and...
Podcast Interview
SERS-based project targets disease biomarkers at point of care In a recent episode of the “All Things Photonics” podcast, Photonics Media spoke with representatives of the Precise Advanced Technologies and Health Systems for Underserved Populations initiative, or PATHS-UP. The National Science Foundation-funded collaboration between research and industry targets the advancement of positive R&D outcomes beyond the lab and into the wider...
BioOpinion
Medical lasers: Defining what to measure Medical lasers are increasingly being used as vehicles for the precise delivery of energy in a variety of applications. The laser beam itself can be used as a treatment tool, cutting specific tissue at the required depth. It also serves as a production tool for the manufacturing of medical components, such as for the cutting and welding of implants. In any of these instances, it is vital to...
Postscripts
Color shopping — how cuttlefish camouflage Scientists have long believed that when cuttlefish camouflage in response to danger, they physiologically choose a color pattern from a limited number of pigmentation schemes to best match their surroundings. But a team of researchers from Asia and Europe has determined it to be a far more complicated process than that. Rather than selecting colors from a limited number of patterns, the common...
Products
FLIM Camera System The LIFA vTAU from Lambert Instruments is a camera-based system designed to transform fluorescence lifetime imaging microscopy (FLIM) for live cell applications. Featuring a single-photon avalanche...
Lambert Instruments BV
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Sapphire and Ruby Balls The Meller Sapphire and Ruby Balls from Meller Optics are miniature high-precision sapphire and ruby balls for use as bearings and mechanical components in medical and scientific instruments and as...
Meller Optics Inc.
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UV High-Speed Cameras The Phantom TMX Series of high-speed cameras from Vision Research offer the ability to capture images in the extended light spectrum of UV, visible, and near-IR wavelengths. The cameras have over 70%...
Vision Research Inc., Phantom Digital High-Speed Cameras
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Smart Imaging System The ECLIPSE Ji from Nikon is a digital inverted microscope and smart imaging system which utilizes AI to automate the acquisition and analysis of cellular images, streamlining research workflows...
Nikon Instruments Inc.
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Microsurgery Digital Microscope The PENTERO® 800 S from ZEISS is a digital microscope used for microsurgery with spines, neurosurgery, and reconstructive surgery. Offering extended optical capabilities, the system offers visual...
Carl Zeiss Meditec AG
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Digital Focus Module The NeuraLeap™ digital focusing module from Bruker is a digital micromirror device (DMD) which enables variable depth-of-field collection for advanced neuroscience research. The module provides...
Bruker Nano Surfaces
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Polarization Camera The CELERA One P from Alkeria is a part of their polarization camera series. Based on a single USB3 interface, the product gives the possibility to perform inspections in a smaller package. With a...
Alkeria srl
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Large Format OpenStand The H275LMT from Prior Scientific is an extended travel motorized focus tower compatible with a variety of optical components, providing users with up to 150 mm of motorized focus travel. The product...
Prior Scientific Inc.
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Optical Spectrum Analyzers The AQ6373E visible wavelength and AQ6374E wide range optical spectrum analyzers from Yokogawa Test & Measurement were developed to meet a variety of optical spectrum measurement needs in both...
Yokogawa Europe BV
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Replicated Transmission Gratings DeepUV gratings from Optometrics offer transmission from 190 - 1100 nm, environmental stability, and enhanced polarization resistance compared to other replicated optics. Available in standard or...
Omega Optical - Gratings Products
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Compact Femtosecond Fiber Laser The Carmel X-515 ultracompact laser head from Calmar Laser is a fiber-based femtosecond laser offered in both a scientific — CDRH compliant — version with front panel control knobs and an...
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Spinal Surgery Vision System The MaxView® 4K System from Viseon Inc. is an advanced visualization system designed for minimally invasive spine surgery. The towerless system features a single-use, sterile 4K imaging...
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Diode Pump Source The G2-A Diode Pump Source from Lumispot Tech is a second-generation continuous-wave pump laser designed to optimize solid-state laser technology. The device offers high efficiency, stability,...
Lumispot Tech
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Mass Photometry Software The SamuxMP software package for Good Manufacturing Practice (GMP) from Refeyn Ltd. expands the application of its SamuxMP and SamuxMP auto mass photometers in adeno-associated virus (AAV)-based gene...
Refeyn Ltd.
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Extended SWIR Hyperspectral Camera The Hinalea Imaging Model 4455 extended shortwave-infrared (XSWIR) hyperspectral camera from SphereOptics GmbH covers the 1200- to 2100-nm range. The camera offers high spectral and spatial...
SphereOptics GmbH
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Fluorophores Alfa Chemistry’s diverse range of fluorophores provides essential components in fluorescent probes. The materials are integral to small-molecule fluorescent probes, equipped with...
Alfa Chemistry
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