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BioPhotonics - May/Jun 2021
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Digital Edition
Features
Smart Probe Captures Biomarker Sequence
A smart probe is a hairpin oligonucleotide, essentially a string of nucleic acids, that is labeled with a fluorophore on one end and tethered with successive guanosine residues on the other end....
Plasmonics and Microfluidics Speed Detection of Lyme Disease
When a person develops Lyme disease from a tick bite, identifying the tiny culprit can be challenging. The insect itself is difficult to see in the grass or forested area it comes from before...
Multiplex Imaging Captures Cellular Processes
Ongoing innovations in optical microscopy have fueled life science research, allowing scientists to visualize how complex biological systems work and break down. These developments have required...
Light Sheet Microscopy Enables 3D Pathology
Pathology for cancer diagnosis today relies on manual processing and an individual’s assessment of 2D samples. While this method has been established for over a century, the process has limitations....
Editorial
Detecting early-stage Lyme
Lyme disease continues to infect a large swath of the population in North America. The reliance on the standard two-tiered serodiagnostic test to identify its presence has proved problematic because the bacteria that cause the disease — Borrelia burgdorferi — can be difficult to trace in the early stages. Some in the biomedical community are pinning their hopes for reliable testing on...
BioScan
Kinetic River Develops Autofluorescence Removal Technology
Flow cytometry instrumentation company Kinetic River Corp. completed a small business innovation research (SBIR) project funded by the National Institutes of Health (NIH). The award funded the...
Coherent Opts to Accept $7B II-VI Takeover Proposal
II-VI will enter into a definitive agreement with Coherent, allowing the Pittsburgh-based optical components and semiconductor materials manufacturer to acquire Coherent, a laser manufacturer. The...
Microscopy Method Resolves Fluorescence at Nanometer Scale
Researchers led by Stefan Hell at the Max Planck Institute (MPI) for Biophysical Chemistry and the Heidelberg-based MPI for Medical Research have developed a light microscopy method, MINSTED, that is...
Laser-based Photoacoustic Method Provides Subcellular Insights
City University of Hong Kong researchers developed a multiwavelength optical resolution photoacoustic microscopy (OR-PAM) system based on a single laser source. The system enables simultaneous...
Light-Controlled Enzymes Show Potential in Medicine, Industry
Research conducted at the University of São Paulo’s Chemistry Institute demonstrated the utility of near-infrared and infrared light for use as catalysts in the control of enzymes. The...
Microscope Detects Chirality to Make Solid-Tissue Imaging Possible
Researchers at the University of Illinois’ Beckman Institute for Advanced Science and Technology developed a spectroscopic microscope enabling optical measurements of molecular conformations...
Optical Tweezing Inspires Nanoscopic Trapping Method
Researchers from the University of Technology Sydney (UTS) have deployed the existing principles of optical tweezer technology, which enables the manipulation and assemblage of nanoparticles, as a...
Features of Mantis Shrimp Eye Inspire Smaller Optical Sensor Design
The ultrasensitive eyes of mantis shrimps are the inspiration behind a new kind of optical sensor that is small enough to fit on a smartphone, yet capable of performing hyperspectral and polarimetric...
AI-Enabled Microscopy Decodes the Immunological Synapse
KAIST researchers have applied deep learning technology to 3D holographic microscopy, demonstrating the microscopy method’s potential for the practical study of cell interactions. The method...
AI-powered Diagnostic Imaging Tool Estimates Hemoglobin Levels
A collaboration between SigTuple Technologies and the Indian Institute of Science demonstrated an AI-powered, imaging-based tool for the estimation of hemoglobin levels. The setup combines a...
OSA Names Recipients of its 2021 Awards
The Optical Society announced 17 recipients of the 2021 OSA awards and medals. The society will recognize a total of 23 awardees throughout the year for their achievements. Among those honored this...
HORIBA Businesses Invest in R&D Site, Acquire MedTest Holdings
HORIBA FRANCE SAS, a developer of Raman spectroscopy systems and technology, inaugurated a new site in Loos, France. The facility replaces the company’s former location in Villeneuve...
BioOpinion
Light therapy and skin treatment: Healing begins beneath the surface
Low-level light therapy uses low incidence levels of photon energy to target tissue to achieve a clinically useful effect without resulting in unintended heat or damage. It has shown dramatic beneficial effects when used for wound healing, pain management, and skin rejuvenation, but it has been slow to receive clinical acceptance. Lasers are more widely used for these types of treatments, but...
Postscripts
Scientists follow fruit fly guidance system
A possible key to developing reliable navigation in autonomous vehicles may have been found through a window into the fruit fly’s brain. With the aid of live calcium imaging and two- photon microscopy, Northwestern University researchers recorded brain activity in neurons located at the base of the flies’ antennae that process external temperature signals. The team put Drosophila melanogaster...
Products
3D Cell-Analysis Software
NoviSight 3D analysis software from Olympus Corp. is designed for life science research that relies on cell analysis. 3D imaging technology and algorithms are combined to create software capable...
Evident
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Medical Camera Module
The OVMed® OCHTA camera module from OmniVision Technologies Inc. is a medical, wafer-level device that improves image quality for single-use endoscopy in deep anatomical access. At 400...
OMNIVISION
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Apochromatic Objective Lenses
Apochromatic objective lenses from II-VI Inc. achieve subwavelength surface regularity and high optical transmission to enable diffraction-limited performance across the full visible spectrum for...
Coherent Corp.
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Horticulture LEDs
LUXEON 3030 HE Plus Horticulture LEDs from Lumileds offer high-PPF/W, broad-spectrum white light to enable productive, economical grow lights. The LEDs are engineered for robust sulfur...
Lumileds
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Confocal Imaging Reader
The Cytation C10 Confocal Imaging Reader from BioTek Instruments Inc. is an automated, multifunctional system for research laboratories and core facilities focused on cell-based research. The...
BioTek Instruments Inc.
Compact Light Microscope
The Primostar 3 compact light microscope from ZEISS is a robust, upright device for daily classroom uses or lab work for tissue and sample examination in histology, cell biology, food, microbiology...
Carl Zeiss Microscopy GmbH, Electron- and Ion-Beam Microscopes
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Biological Imaging Platform
The Endeavor biological imaging platform from Araceli Biosciences delivers high-speed, high-resolution scanning of cell-based assays for drug discovery. The Endeavor combines fast, full-well...
Araceli Biosciences
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Photostimulation Module
The HoloStim-3D holographic photostimulation module from Scientifica Ltd. provides turnkey, integrated Spatial Light Modulation (SLM). By shaping laser beams to generate defined light patterns...
Scientifica Ltd.
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Deep UV Diode Laser Module
The Model 261 deep UV diode laser module from UVC Photonics Corp. provides >10 mW of light at 261 nm. The laser package features a footprint of 20 × 20 × 80 mm, enabling easy...
UVC Photonics
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Compact Spectrometers
The SP series of spectrometers from Spectrolight Inc. are compact, high-performance devices for applications that require a high signal-to-noise ratio and/or dynamic range. Advantages include...
SPECTROLIGHT Inc.
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