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BioPhotonics - March 2015


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Features
Raman Spectroscopy and Microscopy Enable Life Science Discoveries The first article in this two-part series looked at Raman spectroscopy applications in tumor surgery, endoscopy and bacterial identification. This second part examines applications in cell sorting,...
Diverse Applications Drive Lasers for Multiphoton Microscopy After years of domination by a single ultrafast laser technology (Ti:S) and its associated add-ons, laser manufacturers have broadened their technology portfolios to better support a diversified and...
Multiphoton Imaging Takes New Directions Recent evolutions of ultrafast laser technology uniquely overcome key challenges in bioimaging, especially for long-term in vivo imaging, deep penetration and leveraging multimodal imaging...
Lens-Free Microscopy Goes Scalable A compact lens-free microscope could replace microscopes – and even expand their use – in a number of key biomedical applications, such as stem-cell culturing or in vitro drug testing....
Editorial
What Was Your Takeaway? The Photonics Media team is just back from SPIE Photonics West, and you will find coverage in print and online, including a full segment shot on-site for the Feb. 18 edition of the Light Matters weekly newscast. As usual, there was no shortage of new information to consider. I attended the BiOS event with BioPhotonics’ editor, Rodd Pedrotti. It was Rodd’s first trip to the annual show...
BioScan
Smartphone DNA measurements An optomechanical attachment now enables smartphones to perform fluorescence microscopy measurements on DNA. The 3-D-printed device was developed by a team of investigators led by Dr. Aydogan Ozcan at the University of California, Los Angeles.
New Model Could Bring Custom Optogenetics Proteins Deeper understanding of the molecular mechanisms of a light-sensitive protein could lead to more specialized optogenetics techniques. Researchers at Ruhr University Bochum probed channelrhodopsin-2,...
AOM Reaches Unprecedented Speeds A new acousto-optic modulator can steer laser beams at unprecedented speeds, potentially enabling finer light control for microscopy and other applications. The device features a liquid-filled cavity...
Drug Fluoresces, Kills Cancer Under 1 Wavelength A combined imaging and phototherapy technique could help guide surgeons removing chemotherapy-resistant tumors — and kill any cancer cells the surgeons miss. Researchers at Oregon State...
Viruses Reveal Color-Coded Brain A technique for introducing multiple fluorescent labels in vivo could deepen scientists’ understanding of the brain. Researchers at the University of Southampton injected mouse brains with a...
Optogenetics Used to Induce REM Sleep in Mice Optogenetic activation of certain brain cells could be used to induce rapid-eye-movement (REM) sleep, which is crucial for keeping both body and mind healthy. MIT researchers targeted cholinergic...
Tumor-Zapping Endoscope in Development A proposed endoscope that would provide high-quality images of tumors in internal organs could also assist in the delivery of chemotherapy drugs. Spatial frequency domain imaging gives the endoscope...
Photoacoustics Promising for Cervical Cancer Assessment Photoacoustic imaging could one day provide a quicker and less invasive alternative to current methods for detecting cervical cancer. Following a study of 30 cervical tissue samples, researchers at...
Optogenetics Gives 'Read-Write' Access to Brain Combing two light-based techniques has enabled researchers at University College London to both observe and control brain activity in mice. The approach involves simultaneous two-photon optogenetic...
Lens-Free 3-D Microscope Sharp Enough for Pathology A computational lens-free, holographic on-chip microscope could provide a faster and cheaper means of diagnosing cancer and other diseases at the cellular level. Developed by researchers at the...
Stimulating Light Receptors Relaxes Blood Vessels A blood vessel receptor that responds to light could aid more effective treatment of vascular diseases and other medical conditions. A team led by Johns Hopkins Medicine discovered the receptor,...
RapidScan
JPK Opens Expanded Headquarters Citing growing demand for its nanoanalytics products, JPK Instruments has moved into expanded suite of offices and laboratories with increased manufacturing space. The company offers integrated atomic force and optical microscopy systems, as well as solutions for polymer research, surface science and nano-optics. JPK has offices in China, France, Japan, Singapore, the U.K. and Ireland, and opened...
Bioptigen Wins $458K Loan for Validation of Intrasurgical OCT System Bioptigen has been awarded a $458,000 strategic growth loan from the North Carolina Biotechnology Center to support clinical validation of the company’s intrasurgical optical coherence...
LaserMax Names New Chief Sales Officer Chris Tinkle has joined LaserMax as chief sales officer. With 25 years of executive management experience, Tinkle is responsible for building and managing all aspects of the organization’s...
Basler Offers Online Lens Selector A new online lens selector from Basler allows users to quickly and easily identify a suitable lens with the right focal length for their camera application. The user enters the data for their...
Basler Names Manager of Sales, Business Development Mark Williams, Basler’s new sales and business development manager, will be responsible for providing support and application engineering to customers in the U.K. He will work with...
Metz Joins Zeiss Executive Board Dr. Matthias Metz will become a member of the executive board for the Zeiss Group on July 1. Metz will be responsible for the consumer-oriented vision care and consumer optics business groups. For...
Mikrotron Chooses Russian, Swedish Distributors Mikrotron GmbH’s high-speed recording cameras will now be distributed in Russia by Sedatec Ltd. of Moscow and in Sweden by Precision Technic Nordic of Stockholm. Mikrotron develops digital...
Limo Names New Managing Director Anton X. Schmölz has been named a managing director at Lissotschenko Mikrooptik (Limo) GmbH. Schmölz has been with the company as chief financial officer since 2013, and will now oversee...
Sales Up 10 Percent for Endoscopy Firm Mauna Kea Endoscope firm Mauna Kea Technologies grew its revenues by 10 percent in 2014 despite a sales slowdown in the U.S. Sales were €11.0 million, compared to €10.0 million in 2013, with...
Marcellino Appointed to Iridex Board of Directors Dr. George Marcellino, co-founder of OptiMedica Corp. of Sunnyvale, Calif., has been appointed to Iridex’s board of directors. From 1988 to 2003, Marcellino held senior research, sales and...
Emerson Acquires QCL Gas Sensor Firm Cascade Technologies Quantum cascade laser (QCL) gas sensor firm Cascade Technologies Ltd. of Stirling, Scotland, has been acquired by About Emerson Process Management. The terms of the acquisition were not disclosed....
Leica, NovoPath to Integrate Histology Systems Leica Biosystems and software firm NovoPath Inc. of Princeton, N.J., plan to team up to integrate systems for enhanced labelers, stainers and other histology equipment for pathologists. Leica’s...
Delta Spins Out Optical Thin Films Business Delta Danish Electronics, Light & Acoustics has spun off its optical thin films business. Following a management buyout, Delta Optical Thin Film AS will be run by Business Manager Poul Svensgaard...
Zecotek Patent Lawsuit Settled Zecotek Photonics Inc. has settled a patent lawsuit its imaging subsidiary brought against Philips and Saint-Gobain Corp. in 2012. The suit alleged Saint-Gobain’s lutetium fine silicate (LFS)...
CoolLED, Prior Scientific Team Up on Fluorescence Microscopy Illumination Prior Scientific has chosen CoolLED Ltd. as an OEM partner in developing LED illumination for fluorescence microscopy. CoolLED said it was the first to introduce a commercial LED illumination unit...
Mass General, Infraredx Partner to Explore Cardiovascular Imaging Devices Infraredx is teaming up with Massachusetts General Hospital and researcher Dr. Gary Tearney to develop new and combination technologies to provide enhanced information about coronary disease in...
BioLight to Distribute Laser Eye Surgery System in Hong Kong, Macao BioLight Life Sciences Investments Ltd. will distribute IOPtima’s IOPtiMate laser eye surgery system in Hong Kong and Macao, with a purchase commitment of at least nine systems. IOPtiMate is...
3i to Sell Light-Sheet Microscopy Systems under Zeiss Sublicense Intelligent Imaging Innovations (3i) will sell and support lattice light-sheet microscopy development systems under a sublicense with Zeiss’ microscopy business group in Jena, Germany. Also...
Iridex Ophthalmology Lasers to Aid Chinese Health Initiative The Chinese government has ordered $620,000 worth of ophthalmology laser equipment from Iridex Corp. to aid an initiative to bring advanced health care technologies to rural areas of the country....
Postscripts
Vital signs on the run A new, all-organic optoelectronic sensor can be worn like a Band-Aid to measure pulse rate and blood oxygen saturation. OLED = organic LED. Courtesy of Yasser Khan. For fitness enthusiasts interested in tracking their vital signs while engaged in pursuits such as running, hiking or playing tennis, a newly designed pulse oximeter sensor could be a welcome and wearable accessory. The all-organic...
Products
Optical-Compatible AFM A new atomic force microscope (AFM) from Bruker Corp. can be integrated with optical microscopy for biological research into cells, tissues and molecules. The BioScope Resolve provides...
Bruker Optics Inc.
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Infrared LED The IR Oslux SFH 4780S emitter from Osram Opto Semiconductors operates at 810 nm and offers high radiant intensity of 2900 mW/sr at an operating current of 1 A. It is 2.4 mm tall and achieves...
Osram Opto Semiconductors Inc.
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Mechanical Vibration-Isolation Platforms The VIBe VIP100 series of vibration isolation platform by Newport Corp. is designed for laboratory and industrial OEMs. Suitable for small instruments and sensitive applications, the line...
MKS/Newport
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Light-Sheet Imaging The new Ti-diSPIM module from Nikon Instruments Inc. gives light-sheet imaging capabilities to the company’s flagship Ti inverted research microscope. Selective plane illumination...
Nikon Instruments Inc.
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Microscope Camera A new scientific-grade digital microscope camera from BestScope International Ltd. offers color fidelity at a high frame rate. The BHC3-1080P HDMI microscope camera offers 30 fps uncompressed...
BestScope International Ltd.
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Sterilization Camera A new camera module provides legally compliant documentation of the sterilization and packing process in medical facilities. The new XS mini USB cameras from IDS Imaging Development Systems...
IDS Imaging Development Systems Inc.
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Dental Laser Biolase has introduced the Epic X diode laser, the company’s premier and most complete diode laser for dentistry. The Epic X improves upon the Epic 10, with faster procedures for surgery,...
BIOLASE Inc.
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Mini Viewing Cabinet The CM-10MP by Spectroline is a mini viewing cabinet designed for use with laboratory applications that require high-contrast fluorescence analysis. It is compact, portable and made of molded,...
Spectronics Corp., Spectroline
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Intraocular Lens Inspection System The OptiSpheric IOL Pro 2 measurement system by Trioptics can measure up to 100 lenses on a single tray. Designed for high-volume production, the system provides measurement of various types of...
TRIOPTICS GmbH
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Stereo Microscopes Zeiss’ Stemi 305 and Stemi 508 stereo microscopes are designed for use in education applications, as well as lab routine and industrial inspection. They allow users to observe samples in...
Carl Zeiss Spectroscopy GmbH
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Spectrophotometer Optics Craic Technologies has announced the addition of a UV-VIS-NIR polarization spectroscopy optics and hardware for its microspectrophotometers. Users are able to measure polarization spectra in...
CRAIC Technologies
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Diagnostic LCD A new LCD system from NEC Display Solutions of America provides widescreen display for diagnostic review applications in health care organizations. The MultiSync MD212G3 LCD has a 3-MP,...
NEC Display Solutions of America
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Light Engine The LumiBright LE light engine by Innovations in Optics Inc. offers nonimaging optics for large field-of-view fluorescent imagers used in life science instruments. It can direct LED light into...
Innovations in Optics Inc.
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UV-VIS-NIR Spectrophotometer Offering high sensitivity, high resolution and an ultralow stray-light level, the UV-3600 Plus UV-VIS-NIR spectrophotometer from Shimadzu achieves high-accuracy measurements across the entire...
Shimadzu Scientific Instruments Inc.
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3-D Acquisition System The ThunderScan 3-D acquisition system from PhaseView enables ultrahigh-speed volume imaging on single-plane-illumination microscopy platforms. The system is based on a remote focusing method...
PhaseView
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Microscopy Cameras Delivering fluid imaging at full-HD resolution for microscopy applications, the DP22 and DP27 digital cameras from Olympus provide visualization identical to that of oculars. The new cameras...
Olympus Europa SE & Co. KG
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