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BioPhotonics - Jan/Feb 2025
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Issue Library
Digital Edition
Features
Fluorescence LED Illumination Systems Can Be Customized for Life Sciences Applications
Automation is a widespread trend across the life sciences, maximizing throughput and efficiency in applications such as drug development and clinical testing. For example, high-throughput screening...
Tapping the Terahertz: Capturing Clues in Tissue Hydration
Due to its low photon energy and ability to penetrate certain types of materials, terahertz imaging holds a great deal of promise for the identification of key biological indicators —...
LEDs and Multi-Bandpass Filters Work in Tandem to Transform Fluorescence Instrumentation
Fluorescence stands as a cornerstone technology in the realm of bioanalysis. Fluorescence is one of the most sensitive spectroscopic quantification techniques, and fluorescence microscopy methods,...
NIR Spectroscopy Provides a Chemical Perspective on the Composition of Teeth
While dentistry has become increasingly sophisticated, uncertainties still exist in the diagnosis and treatment of dental conditions that are left to the discretion of the practitioner. Part of the...
Editorial
Terahertz gets skin-deep
Due to high absorption in water, terahertz waves don’t travel deeply in tissue. So, in the clinic, terahertz imaging has often focused on surface water content and structural details — ideally suited for dermatology. Those who enjoyed the related theme last issue will learn more in this edition about what the terahertz regime may offer in skin cancer diagnostics and ulcer...
BioScan
Leibniz-IPHT, SUNY Albany Open BioPhotonic Tech Center
The Leibniz Institute of Photonic Technology (Leibniz-IPHT) and the State University of New York at Albany (SUNY Albany) have established the Center for Biophotonic Technology and Artificial...
Hamamatsu Acquires BAE Systems Imaging
Through its subsidiary Photonics Management Corp., Hamamatsu Photonics K.K. has acquired BAE Systems Imaging, a San Jose, Calif.-based semiconductor manufacturer specializing in high-performance CMOS...
Laser Photonics to Acquire Control Micro Systems
Developer of industrial cleaning laser systems Laser Photonics Corporation (LPC) has signed a definitive agreement to acquire Control Micro Systems, Inc. (CMS), a provider of laser solutions for the...
Raman Spectroscopy Undergoes Major Speed Upgrade
Researchers at the University of Tokyo have increased the measurement rate of Raman spectroscopy by 100-fold. Since the measurement rate of the technique has been a major limitation, the improvement...
IPG Photonics to Acquire cleanLASER
IPG Photonics has signed a definitive agreement to acquire Clean-Lasersysteme GmbH (cleanLASER), a developer of laser cleaning systems. The transaction is expected to close later this year. Based in...
Silicon Photonics Drives Optical Tweezer Innovation
Compared to bulk optical tweezers, integrated optical tweezers are compact and low-cost, making them practical for most research organizations. But so far, integrated optical tweezers have been of...
Expansion Microscopy Technique Enables 20-nm Resolution
A new expansion microscopy (ExM) technique from MIT makes it possible to use a conventional light microscope to generate high-resolution images at the nanoscale, by expanding specimens 20-fold before...
Photoacoustics Captures Anomalies in Microvasculature
By using a laser to generate ultrasound waves that reveal structural changes, photoacoustic tomography (PAT) has shown its value in identifying disease conditions in the microvasculature, the tiny...
Surgical Microscope Uses OCT to Define Precise Tumor Margins
A megahertz-speed optical coherence tomography (MHz-OCT) instrument, integrated with a neurosurgical microscope, has demonstrated the ability to acquire high-quality, volumetric, cross-sectional...
OLED Probes Guide Optogenetic Light to Cochlear Implants
Electrical cochlear implants (eCIs) are effective at restoring hearing when used in a quiet environment. However, eCIs do not work as well in noisy surroundings, and they are unable to fully capture...
3 Questions
3 Questions with Weijian Yang
BioPhotonics spoke with Weijian Yang, an associate professor in the department of electrical and computer engineering at the University of California, Davis and a leader of a team that developed a two-photon fluorescence microscope that captures high-speed neural activity. The system, described in Optica, uses a line of light, rather than a dot of light, to scan and illuminate the brain area...
BioOpinion
The Brave New World of Diagnostic R&D
Optical technologies have revolutionized many aspects of modern health care. From automated microscopy and digital pathology to diverse bioanalytic platforms, optics are central to laboratory diagnostics. Molecular (i.e., DNA/RNA-based) diagnostics epitomize the value of photonic-driven technology. Nucleic acid amplification testing and next-generation sequencing rely largely upon fluorescence...
Postscripts
You’re gonna need a bigger LED strip
Duunnn dunnn … duuuunnnn duun … duuunnnnnnnn dun dun dun dun dun dun dun dun: This is presumably the tune that plays in every swimmer’s mind when they wade into the open ocean. But it may just be the right light display, rather than the right musical intonation, that could keep that threat in the shadows. While John Williams’ score helped strike fear into the hearts of...
Products
Plug-and-Play Stage
The VCDS-025-038-02-B1-01 from Moticont is a plug-and-play linear voice coil stage for applications such as positioning, assembly, laser cutting, welding and drilling, clamping, medical diagnostics...
Moticont
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Photochemistry Reactors
Asynt’s range of photochemistry reactors can be used in both batch and flow equipment. The reactors scale reactions from mg to potentially multiple kg with smaller batch photochemical reactors...
Asynt Ltd.
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Piezo Stage Family
The P-545 PInano® family from PI is a piezo stage family for applications including biological imaging, semiconductor inspection, photonics testing, particle tracking, 3D imaging, and...
PI (Physik Instrumente) LP, Motion Control, Air Bearings, Piezo Mechanics
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Suppression Filter
The ASE Shield from TeraXion is an amplified spontaneous emission (ASE) suppression filter developed to eliminate ASE at the source in applications such as spectral combining, telecommunications,...
TeraXion Inc.
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Compact DPSS Lasers
Frankfurt Laser Company’s line of compact DPSS lasers were designed to provide solutions for a wide range of industrial, medical, scientific, and optical applications. The lasers have an...
Frankfurt Laser Company
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IR LED Chip
The IR:6 technology from ams OSRAM is a thin-film LED chip technology for use in medical equipment and IR LED emitters used in manufacturing applications. The technology can emit light at a 920-nm...
ams OSRAM
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RGB-IR USB Camera
The See3CAM_CU83 from e-con Systems is a 4K RGB-IR USB camera for applications including biometric access control, in-cabin monitoring, crop health monitoring, image-guided surgeries, and smart...
e-con Systems India Pvt. Ltd.
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Eight-Channel Spectrophotometer
The DS-8X from DeNovix is an eight channel spectrophotometer designed for full spectrum 1 µL UV-Vis measurements from 190 - 840 nm for DNA, RNA, and protein quantification. The standalone...
DeNovix Inc.
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Optical Phantoms
Edmund Optics’ OCT and diffuse reflectance phantoms provide off-the-shelf, standardized ready-to-use tools for the calibration and optimization of imaging systems in research and clinical...
Edmund Optics
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Optical Water Analyzers
The UviTec™ analyzer product family from ABB are optical analyzers for the inspection of water sources and for the wastewater industry. Including optical sensors, controllers, a suite of add-on...
ABB Ltd.
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Miniature Microscope
The SUPERNOVA-600 from Transcend Vivoscope is a miniature microscope for real-time microscopic in vivo imaging of neuronal and cellular activities in the brain. The SUPERNOVA-600 incorporates the...
Transcend Vivoscope
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Optical Filter Sets
The Newport™ ODiate® Fluorescent Filter Sets from MKS Instruments are single band optical filter sets designed for wavelength ranges of common fluorophores used in fluorescent imaging. The...
MKS Instruments Inc.
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Bioimaging Platform
The HT-X1™ Plus from Tomocube is a bioimaging platform for capturing 3D images of cells and organoids for biomedical research applications. The platform is equipped with a CXP camera and...
Tomocube Inc.
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Confocal Raman Microscope
The Apollo M from CRAIC Technologies is a confocal Raman microscope for applications such as materials research, nanotechnology, pharmaceuticals, biomaterials, and semiconductor analysis. The...
CRAIC Technologies
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Immunofluorescent Staining Reagent Kit
The CellO-IF from AMS Biotechnology is an immunofluorescent (IF) staining reagent kit designed to accelerate the labeling of organoids and spheroids directly in hydrogels or extracellular matrices,...
AMS Biotechnology Ltd.
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Microscope Lens
The TITANITE lens from Schneider-Kreuznach is a lens specifically for microscopy applications in medical and biological research. The lens is optimized for 5× magnification and enables the...
Jos. Schneider Optische Werke GmbH, Industrial Solutions
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Line-Scan Camera
The photonLINE from Photonfocus is a line scan camera designed for applications such as surface inspection, transport, recycling, printing, medicine, and pharmaceuticals. The camera’s software...
Photonfocus AG
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UVC Line Light
The COBRA Slim UVC from ProPhotonix is a UVC LED line light for applications including surface inspection, machine vision, pharmaceutical and medical package inspection, food and beverage inspection,...
ProPhotonix Ltd.
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