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Oxford Instruments WITec GmbH - Raman Microscope LB 12/25

ZEISS-Alpenglow Biosciences Partner on 3D Pathology Tech

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ZEISS has partnered with Alpenglow Biosciences, a 3D spatial biology company, to jointly develop an inverted light-sheet microscope and bioinformatics pipeline tailored for clinical applications. By combining the companies’ respective technologies, the collaboration aims to enable the broader adoption of 3D pathology across research, translational, and clinical applications.

“Together, we are introducing an integrated solution for analyzing entire tissue samples and improving reproducibility to meet the evolving needs of both translational research and clinical settings,” said Michael Albiez, head of ZEISS Research Microscopy Solutions. “This collaboration will enable researchers and clinicians to gain deeper insights into tissue and cellular structures with greater efficiency and precision, ultimately facilitating more personalized and effective treatments."

The partnership will combine ZEISS’ engineering and arivis visualization platform with Alpenglow’s data processing and AI capabilities. Once imaged, a GPU-accelerated imaging analytics pipeline could allow users to go from tissue to clinically impactful insights at the same time or faster than traditional pathology workflows.

According to the partners, the generation of 3D images from entire tissues provides opportunities for AI to make individualized treatment predictions for patients.
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Published: May 2025
Glossary
artificial intelligence
The ability of a machine to perform certain complex functions normally associated with human intelligence, such as judgment, pattern recognition, understanding, learning, planning, and problem solving.
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