An R&D group led by Professor Yoshifumi Saijo of Tohoku University and Noriyuki Masuda of Advantest Europe GmbH has succeeded in developing in vivo skin imaging technology that can simultaneously generate dual-wavelength photoacoustic images and ultrasound images.

As part of the “Innovative Visualization Technology to Lead to Creation of a New Growth Industry” project operated under Japan’s Council for Science, Technology, and Innovation through its Impulsing Paradigm Change through Disruptive Technologies Program (ImPACT), the newly developed in vivo imaging technology utilizes a focused ultrasonic sensor that can detect multiple ultrasonic signals. Thus, photoacoustic waves and ultrasonic waves can be measured with the same sensor while signals are generated on two alternating wavelengths, allowing the detection of ultrasonic waves that image the microvascular network in the dermis as well as blood oxygen saturation. Using the acquired data, mapping of oxygen saturation and the superposition of photoacoustic images and ultrasound images is possible.

Biopsy studies have proved that signs of skin aging such as spots and wrinkles are related to microvessels in the skin. The newly developed photoacoustic imaging method is expected to be used for monitoring of photoaging of the skin as well as other applications.