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Unprecedented Spatially Resolved Chemical Analysis Via Nanoscale Spectroscopy

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Kevin Kjoller, Craig Prater and Roshan Shetty, !%Anasys Instruments Corp.%!

The phrase “lab on a tip,” referring to nanoscale property measurements made by the probe of an atomic force microscope (AFM), has been a dream for the developers of analytical instrumentation. There also has been a drive for “hyphenated techniques” that make multiple types of complementary measurements simultaneously. This has been driven with investment in nanotechnology in many fields, notably in the materials and life sciences, especially for studies that correlate structure and property or function. Looking at a polymer company, one sees that many analytical...Read full article

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    Published: December 2010
    Glossary
    nanotechnology
    The use of atoms, molecules and molecular-scale structures to enhance existing technology and develop new materials and devices. The goal of this technology is to manipulate atomic and molecular particles to create devices that are thousands of times smaller and faster than those of the current microtechnologies.
    spatial resolution
    Spatial resolution refers to the level of detail or granularity in an image or a spatial dataset. It is a measure of the smallest discernible or resolvable features in the spatial domain, typically expressed as the distance between two adjacent pixels or data points. In various contexts, spatial resolution can have slightly different meanings: Imaging and remote sensing: In the context of satellite imagery, aerial photography, or other imaging technologies, spatial resolution refers to the...
    total internal reflection
    The reflection that occurs within a substance because the angle of incidence of light striking the boundary surface is in excess of the critical angle.
    AFMAlexandre Dazzianalytical instrumentationAnasys Instruments Corp.atomic force microscopyattenuated total reflection spectroscopyBasic Sciencebiodegradable polymerschemical characterizationchemicalsConsumerCurtis MarcottFeaturesFourier transform infraredFranceFTIRIR spectroscopyKatherine Willetslife sciencesmaterials sciencesMicroscopynanoIRnanotechnologyNational Science FoundationNISTnylonpolyethylene terephthalatepolymersRoshan Shettyspatial resolutionTest & Measurementtotal internal reflectionUniversité Paris-SudUniversity of Texas AustinLasers

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