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Retinal OCT and Genetics Identify Links Between Ocular and Systemic Health

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BOSTON, Feb. 1, 2024 — A study conducted by Mass Eye and Ear, the Broad Institute at MIT, and Harvard Medical School has demonstrated links between the thinning of different retinal layers and an increased risk of disease. The work used OCT retinal images and genetic data from thousands of UK Biobank participants and could serve to advance the use of OCT to predict ocular disease and inspire further research on disease prediction beyond the eye. The researchers analyzed data from more than 44,000 UK Biobank participants who underwent OCT retinal imaging and genotyping in 2010. The participants were...Read full article

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    Published: February 2024
    Glossary
    ophthalmology
    Ophthalmology is a branch of medicine that focuses on the anatomy, physiology, and diseases of the eyes and visual system. Ophthalmologists are medical doctors who specialize in the diagnosis, treatment, and prevention of eye disorders and diseases. They are trained to provide comprehensive eye care, including medical, surgical, and optical interventions. Key areas within ophthalmology include: General eye care: Ophthalmologists perform routine eye examinations to assess visual acuity,...
    optical coherence tomography
    Optical coherence tomography (OCT) is a non-invasive imaging technique used in medical and scientific fields to capture high-resolution, cross-sectional images of biological tissues. It provides detailed, real-time, and three-dimensional visualization of tissue structures at the micrometer scale. OCT is particularly valuable in ophthalmology, cardiology, dermatology, and various other medical specialties. Here are the key features and components of optical coherence tomography: Principle of...
    Research & TechnologyeducationAmericasMass Eye and EarMass General BrighamBroad InstituteHarvard Medical SchoolImagingLight SourcesOpticsBiophotonicsmedicalophthalmologyoptical coherence tomographyretinal imagingretinal OCTgeneticseye diseases

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