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Photoacoustic Imaging Technique Detects Arterial Plaques

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Researchers at Michigan State University (MSU) used light-activated nanoparticles and photoimaging to locate and image cells found in the arteries, cells that could lead to heart attacks and strokes. MSU professor Bryan Smith and his team worked with researchers from Emory and Stanford universities to develop nanoparticles made from carbon (i.e., carbon nanotubes) that selectively target the types of immune cells that are abundant in inflammatory plaques. Though it is difficult to prove whether a particular plaque is responsible for a stroke or heart attack, the prevailing belief is...Read full article

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    Published: August 2021
    Glossary
    flow cytometry
    Flow cytometry is a powerful technique used in biology and medicine for the quantitative analysis of the physical and chemical characteristics of cells and particles suspended in a fluid. The method allows for the rapid measurement of multiple parameters simultaneously on a cell-by-cell basis. It is widely used in various fields, including immunology, microbiology, hematology, and cancer research. Here are the key components and features of flow cytometry: Sample preparation: Cells or...
    photoacoustic imaging
    Abbreviated PAI. An imaging modality with a hybrid technique based on the acoustic detection of optical absorption from endogenous chromophores or exogenous contrast agents. Light is absorbed by the chromophores and converted into transient heating, and through thermoelastic expansion there is a resulting emission of ultrasonic waves. In tissue, ultrasound scatters less than light, therefore PAI generates high-resolution images in the diffusive and optical ballistic regimes compared to purely...
    nano
    An SI prefix meaning one billionth (10-9). Nano can also be used to indicate the study of atoms, molecules and other structures and particles on the nanometer scale. Nano-optics (also referred to as nanophotonics), for example, is the study of how light and light-matter interactions behave on the nanometer scale. See nanophotonics.
    Research & Technologyeducation. AmericasMichigan State Universityflow cytometryImagingLight SourcesMaterialsOpticsphotoacoustic imagingOptoacoustic imagingmyocardial infarctionstrokeBiophotonicsphotoacoustic effectmedicalnanoBioScan

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