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Optogenetics Tests Memory Manipulation Theory

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Optogenetics is giving scientists a better look at how different parts of the brain can work together to manipulate memories. Using the light-based technique, researchers at the University of California, Davis, have been able to erase specific memories in mice. Their findings prove the basic theory of how different parts of the brain will work together to retrieve episodic memories, they said. The researchers used mice genetically modified to make their nerve cells fluoresce green when activated by light and to make the cells express a protein that allows them to be switched off...Read full article

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    Published: October 2014
    Glossary
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    BiophotonicsResearch & TechnologyLight SourcesOpticsfiber opticsAmericasoptogeneticsUniversity of California Davisepisodic memoriescortexhippocampusBrian WiltgenWhitehall FoundationMcKnight FoundationNakajima FoundationNational Science FoundationBioScan

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