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Excelitas Technologies Corp. - X-Cite Vitae LB 11/24

Optogenetic Enables Fatigue-Resistant Muscle Control

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Using optogenetics, MIT researchers developed a neuromodulation method that could someday help people with amputations, paralysis, and other conditions that restrict movement to regain muscle control for extended periods of time. The researchers showed that functional optogenetic stimulation (FOS) can enable fatigue-resistant control of muscles with higher accuracy and higher generated force than functional electrical stimulation (FES). For decades, researchers have explored the potential of FES to control muscles in the body. This method uses electrodes implanted in the body to...Read full article

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    Published: June 2024
    Glossary
    optogenetics
    A discipline that combines optics and genetics to enable the use of light to stimulate and control cells in living tissue, typically neurons, which have been genetically modified to respond to light. Only the cells that have been modified to include light-sensitive proteins will be under control of the light. The ability to selectively target cells gives researchers precise control. Using light to control the excitation, inhibition and signaling pathways of specific cells or groups of...
    Research & TechnologyeducationMITMassachusetts Institute of TechnologyAmericasoptogeneticsroboticsLight SourcesOpticsSensors & DetectorsBiophotonicsmedicalfunctional optogenetic stimulationfunctional electrical stimulationdisabilitiesparalysisneuromuscular diseaseneuromodulationBioScan

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