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Meadowlark Optics - Wave Plates 6/24 LB 2024

Novel Platform Reveals Insights into Control of Brain Network

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Researchers at the University of North Carolina (UNC) School of Medicine combined fiber photometry with functional magnetic resonance imaging (fMRI) to examine the dynamic activity of brain regions related to the brain’s default mode network (DMN). With the help of Stanford University scientists — and advanced computational modeling — the researchers obtained results that could provide a more informed model for translational studies. The fMRI-compatible, four-channel, spectrally resolved, optical fiber photometry recording system used for the research is based on a...Read full article

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    Published: February 2023
    Glossary
    fiber photometry
    An optical recording technique that uses light source(s), a beamsplitting cube, light detector(s) and an optical fiber chronically implanted in animal brain to deliver excitation light to neurons tagged with a fluorescent calcium indicator(s) and to collect their overall calcium activity-induced fluorescence. The measured changes in fluorescence intensity are related to the underlying neuronal activity.
    photometry
    Photometry is the branch of science that deals with the measurement of light, particularly in terms of its intensity and the way the human eye perceives it. It involves the quantification of visible light and its characteristics, such as brightness and color. Photometric measurements often consider the spectral sensitivity of the human eye to different wavelengths of light and use standardized units to express light intensity. In astronomy, photometry is used to study the brightness of...
    optical fiber
    Optical fiber is a thin, flexible, transparent strand or filament made of glass or plastic used for transmitting light signals over long distances with minimal loss of signal quality. It serves as a medium for conveying information in the form of light pulses, typically in the realm of telecommunications, networking, and data transmission. The core of an optical fiber is the central region through which light travels. It is surrounded by a cladding layer that has a lower refractive index than...
    BiophotonicsbrainImagingSensors & DetectorsmedicalAmericasResearch & TechnologyeducationFiber PhotometryphotometryUNCUniversity of North Carolina - Chapel Hilldiseasefunctional magnetic resonance imagingfMRIneurological disordersbrain activityoptical fiberfiber opticsneurophotonicsBioScan

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