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New Imaging Technique Could Help Diagnose, Monitor Retinal Disease

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BETHESDA, Md., March 29, 2019 — Researchers at the U.S. National Eye Institute (NEI) believe their adaptive optics indocyanine green (AO-ICG) imaging technique could be used to help diagnose and monitor the progression of eye diseases, and to preclinically detect cellular-level damage to the retinal pigment epithelium (RPE) by nondestructively charting changes in the fluorescent RPE mosaic over varying periods of time. Mosaic of retinal pigment epithelial cells, visualized with indocyanine green (ICG) and adaptive optics. Courtesy of Johnny Tam/U.S. National Eye Institute. The researchers are using in vivo...Read full article

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    Published: March 2019
    Glossary
    ophthalmoscopy
    Also referred to as fundus photography, ophthalmoscopy is the dioptrical study of the various interior components of the eye such as the macula, fovea, and opticdisk, and is overall essential in determining the health of the retina and vitreous humor.
    adaptive optics
    Adaptive optics (AO) is a technology used to improve the performance of optical systems by reducing the effects of atmospheric distortions. The Earth's atmosphere can cause light passing through it to experience distortions, resulting in image blurring and degradation in various optical applications, such as astronomical observations, laser communications, and imaging systems. Adaptive optics systems actively adjust the optical elements in real-time to compensate for these distortions. Key...
    Research & TechnologyAmericasOpticsNational Eye Instituteophthalmoscopyadaptive optics

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