Flow cytometry instrumentation company Kinetic River Corp. completed a small business innovation research (SBIR) project funded by the National Institutes of Health (NIH). The award funded the development of the company’s “Colorado” automated autofluorescence removal technology. “Through a combination of hardware and algorithm development, we have been able to demonstrate the removal of the autofluorescence contribution from a population of exogenously stained eosinophils — a cell type with notoriously high autofluorescence signal,” said Giacomo Vacca, president of Kinetic River. The completion of the Phase I program paves the way for further development and commercialization of a four-laser, 16-channel Colorado instrument with fully automated removal of the contribution from cellular autofluorescence, the goal of a Phase II SBIR proposal recently submitted to the NIH.