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Harmonic Optical Tomography Images Nonlinear Samples in 3D

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Harmonic optical tomography (HOT) is a new technique for imaging microscopic, nonlinear, and inhomogeneous objects. It uses holographic information to generate 3D images of the sample. It is the result of a collaboration between researchers at the University of Illinois at Urbana-Champaign’s Beckman Institute for Advanced Science and Technology and Colorado State University. “Our lab specializes in using holographic data to investigate live cells and tissues,” professor Gabriel Popescu said. “We wanted to extend this technique to nonlinear samples by combining...Read full article

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    Published: June 2020
    Glossary
    nonlinear optics
    Nonlinear optics is a branch of optics that studies the optical phenomena that occur when intense light interacts with a material and induces nonlinear responses. In contrast to linear optics, where the response of a material is directly proportional to the intensity of the incident light, nonlinear optics involves optical effects that are not linearly dependent on the input light intensity. These nonlinear effects become significant at high light intensities, such as those produced by...
    holography
    Holography is a technique used to capture and reconstruct three-dimensional images using the principles of interference and diffraction of light. Unlike conventional photography, which records only the intensity of light, holography records both the intensity and phase information of light waves scattered from an object. This allows the faithful reproduction of the object's three-dimensional structure, including its depth, shape, and texture. The process of holography typically involves the...
    Research & TechnologyeducationAmericasBiophotonicsImagingSensors & DetectorsMicroscopyOpticsnonlinear opticsLight Sources3D imagingholographyoptical tomographyharmonic optical tomographycancerTech PulseBioScan

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