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Meadowlark Optics - Wave Plates 6/24 LB 2024

Confocal Raman Microscopy Studies Drug-Membrane Interactions

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Lauren I. Rugani

Investigating drug-membrane interactions, such as a drug’s ability to pass through a membrane or to bind to proteins within it, helps researchers understand the effects of drugs on membrane functions. Christopher B. Fox, Robert A. Horton and Joel M. Harris of the University of Utah in Salt Lake City have applied optical-trapping confocal Raman microscopy to study the accumulation of salicylate and ibuprofen within phospholipid vesicles and to determine the disordering effects of the drugs on the lipid membranes. The optical-trapping confocal Raman microscope setup includes a Kr+ laser...Read full article

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    Published: August 2006
    Basic Sciencedrug-membrane interactionsFeaturesMicroscopyphospholipid vesiclesRaman microscopySensors & Detectors

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