SEATTLE, April 10, 2024 — An approach to deep brain imaging developed at the University of Washington uses microprisms to provide stable tracking of neuronal activity over a large field of view. According to the research team, the microprism technique is a significant improvement over existing imaging methods used to characterize neuronal ensemble dynamics within deep brain tissues. Organisms rely on their brains’ complex neural circuits to process information and perform functions that will help them find

Mar 14, 2024 — When used appropriately, a laser scanning confocal fluorescence microscope is a valuable tool for researchers to make quantitative measurements in cells and tissue across various life sciences applications. The laser scanning confocal...

HONG KONG, March 11, 2024 — Collaborating researchers from Hong Kong, China, and Germany have developed a quantum-sensing technology that encodes changes in fluorescence intensity into spikes that occur during optically detected magnetic resonance (ODMR) measurements. The...

GENOA, Italy, Feb. 23, 2024 — Image scanning microscopy (ISM), a superresolution technique enabled by the advent of fast and compact detector arrays, provides better signal-to-noise ratio (SNR), optical sectioning, and spatial resolution better than that of a traditional...

BILLERICA, Mass., Feb. 7, 2024 — In separate transactions, Bruker has acquired preclinical in-vivo optical imaging systems company Spectral Instruments Imaging (SII), and Nanophoton Corporation, a provider of advanced research Raman microscopy systems. Financial terms of the...

BONN, Germany, Feb. 5, 2024 — A new software program can map the movements of multiple particles within cells simultaneously, providing insight into cellular functions that are difficult — and sometimes impossible — to investigate using single-cell tracking methods....

Jan 16, 2024 — Stimulated Raman scattering (SRS) microscopy has shown enormous potential in revealing molecular structures, dynamics, and couplings in complex systems. Yet, the sensitivity of SRS is fundamentally limited to millimolar level due to the shot noise...

EDMONTON, Canada, Jan. 5, 2024 — A targeted spectroscopy system developed at Zilia Inc., by a team led by professor Dominic Sauvageau from the University of Alberta, enables concurrent imaging of the eye fundus — a region at the back of the eye — and analysis of...

OEIRAS, Portugal, Nov. 27, 2023 — Superresolution radial fluctuations (SRRF), a superresolution algorithm, works by observing fluctuations in radial symmetry throughout the frames of an image. SRRF supports live-cell, superresolution microscopy on a range of microscopy platforms...

DAEJEON, South Korea, Nov. 22, 2023 — Until now, scientists have relied on fluorescence microscopy techniques to study intracellular cargo transport, a vital process to maintaining essential cellular functions. However, the effects of photobleaching and the visual isolation of cellular...

BALTIMORE, Nov. 7, 2023 — Photoimmunotherapy targets cancer cells with microscopic, nano-engineered cancer drugs that are light-activated at the lesion site. Although the technology is increasingly used to treat metastatic cancer, tools to improve the effectiveness of...

Nov 3, 2023 — Scientists are increasingly turning to live-cell imaging to track changes at the developmental stage of life, which is vital for the advancement of cellular biology, and to grow and monitor proliferating stem cells and cancer cells in a contained...

QINGDAO, China, Sept. 20, 2023 — An on-demand optical system for exporting target droplets from a static droplet array (SDA) provides a simple way to export specific cells or analytes for analysis without compromising efficiency or accuracy. Researchers at the Qingdao Institute of...

Sep 3, 2023 — Diffuse reflection spectroscopy and fluorescence spectroscopy are having a major effect in medicine and the life sciences, with expanding application in physics, chemistry, biology, and medicine. And fiber optic-based probes are becoming an...

Sep 3, 2023 — In many academic research and medical settings, microscopy and imaging have transitioned from using traditional lamp illumination, such as mercury and Xenon lamphouses, to solid-state LED technologies. The benefits of moving to LEDs include long...

Sep 3, 2023 — Holger Schmidt, Ph.D., distinguished professor of electrical and computer engineering and the Narinder Singh Kapany chair of optoelectronics in the Baskin School of Engineering at UC Santa Cruz, discusses the application of signal processing...

NOMI, Japan, Aug. 15, 2023 — A research group from Japan Advanced Institute of Science and Technology (JAIST) developed light-activatable, liquid metal (LM) nanoparticles for cancer diagnosis and treatment via photoimmunotherapy. The LM nanoparticles can target and destroy...

BOCHUM, Germany, Aug. 10, 2023 — To build a flexible sensor for optically detecting a range of viruses and bacteria, a group of researchers from Ruhr University Bochum (RUB), the Fraunhofer Institute for Microelectronic Circuits and Systems (IMS), and ETH Zurich used...

BOSTON, Aug. 10, 2023 — Diffuse in vivo flow cytometry (DiFC), an optical technique developed at Northeastern University, enables fluorescence detection of tumor cells circulating in the bloodstream. It is a promising technique for detecting cancer that has metastasized....

Jul 3, 2023 — Fluorescence polarization (Fpol) is an optical phenomenon that characterizes the polarization of fluorescence emissions relative to the polarization state of the excitation light. It is sensitive to factors that influence the rotational motion of...

Jul 3, 2023 — The rapid spread of COVID-19 and other diseases has shown that understanding viral infection is critical to the health of people around the world. In particular, understanding the dynamics of the earliest stages of infection is important for...

Jul 3, 2023 — Hyperspectral imagers provide an image that produces a detailed spectrum for every pixel, capturing very minute details in a sample. Typically, this technology has been used to measure the spectral reflectance of materials such as agricultural...

LOS ANGELES, May 11, 2023 — Researchers led by UCLA professor Aydogan Ozcan developed a deep learning-enabled biosensor for multiplexed, point-of-care (POC) testing of disease biomarkers. POC biosensors provide remote and resource-limited communities with an economical,...

May 5, 2023 — Men and women respond differently to stimuli, and their hearts respond differently, too. Scientists are continuing to develop an understanding as to why these disparities in physical reactions exist. Before studying the differences in human hearts,...

AMSTERDAM, April 13, 2023 — The University of Amsterdam research team that introduced the red fluorescent protein known as mScarlet in 2016 has introduced an improved variant of the marker. A version of mScarlet called mScarlet3 delivers a quantum yield of 75% and a...